Navigation Links
Gene Study Sheds Light on Often Fatal Heart Condition
Date:6/17/2011

FRIDAY, June 17 (HealthDay News) -- Researchers have pinpointed a genetic risk factor for a potentially fatal heart problem called thoracic aortic dissection.

The life-threatening condition was the cause of the sudden death of actor John Ritter in 2003 at the age of 54.

Now, genetics researchers at the University of Texas Health Science Center at Houston and the Baylor College of Medicine found that people with duplications in DNA in a region of chromosome 16, designated 16p13.1, have a 12-fold increased risk for thoracic aortic aneurysm, an abnormal bulge caused by weakness in the wall of the aorta, the largest artery in the body. The aneurysm can lead to an aortic dissection -- a usually fatal tear in the aorta.

The new findings were published June 16 in the online journal PLoS Genetics.

"The results of this study could affect clinical care because it appears patients with 16p13.1 duplications have an aggressive form of the thoracic aortic disease that causes aneurysms to dissect at smaller diameters," the study's senior author, Dr. Dianna Milewicz, professor and the President George H.W. Bush chair in cardiovascular research, and director of the medical genetics division at the University of Texas Medical School at Houston, said in a journal news release.

"Once doctors are able to use the entire genome, people with duplications in 16p13.1 would need to have their aortas monitored," Milewicz said.

Each year in the United States, about 10,000 people die from thoracic aortic aneurysm and dissection, making it the 15th leading cause of death in the nation, according to background information in the news release.

While aneurysms usually have no obvious symptoms until they dissect or become very large, the U.S. National Library of Medicine states that the most common sign of aortic dissection is a sudden severe onset of chest pain described as a sharp, tearing sensation.

More information

The Society for Vascular Surgery has more about thoracic aortic aneurysm.

-- Robert Preidt

SOURCE: PLoS Genetics, news release, June 16, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Despite Treatment, Employees with Depression Generate Higher Absentee Costs, According to Thomson Reuters Study
2. American Council on Exercise (ACE) Study Reveals Kettlebells Provide Powerful Workout in Short Amount of Time
3. TV drama can be more persuasive than news program, study finds
4. Study carried out into biological risks of eating reptiles
5. Neuroimaging study may pave way for effective Alzheimers treatments
6. Study finds racial gaps continue in heart disease awareness
7. Luth Researchs IndicatorEDG(TM) Study Finds Americans Hopes of Achieving Their Dreams Are Fading
8. First blinded study of venous insufficiency prevalence in MS shows promising results
9. Soothing infants with food focus of childhood obesity study
10. People with anxiety disorder less able to regulate response to negative emotions, study shows
11. American Heart Association Rapid Access Journal Report: Study Finds Racial Gaps Continue in Heart Disease Awareness, Low Knowledge of Heart Attack Warning Signs Among Women
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Gene Study Sheds Light on Often Fatal Heart Condition
(Date:6/23/2017)... , ... June 23, 2017 , ... ... is needed and will ultimately do significant harm to people with all chronic ... , "While it leaves in place the Affordable Care Act (ACA) requirement ...
(Date:6/23/2017)... ... 2017 , ... Dr. Ran Y. Rubinstein , a ... offering three new minimally invasive procedures to patients who want a younger and ... Rubinstein is excited to bring microneedling, microneedling facials, and platelet rich plasma (PRP) ...
(Date:6/23/2017)... ... June 23, 2017 , ... ... essential, and two new videos highlight the importance of correctly using a meat ... Ph.D., who has done extensive research on consumer food safety habits. Dr. Bruhn ...
(Date:6/23/2017)... ... June 23, 2017 , ... Ross Insurance Agency ( http://www.rossinsuranceagency.com ... Emergency Management Agency’s (FEMA) recent update of flood zones, more people than ever ... Act was enacted to reflect the actual risk in flood zone areas during ...
(Date:6/23/2017)... ... June 23, 2017 , ... All-Star Insurance, a family managed ... clients throughout eastern Texas, is announcing the launch of a new charity drive to ... statistics in the United States reveal that an estimated 252, 710 new cases of ...
Breaking Medicine News(10 mins):
(Date:6/7/2017)... URBANDALE, Iowa , June 6, 2017  Diplomat Specialty Infusion ... a sterile compounding environment to its Iowa ... Urbandale now features an ISO 7 cleanroom—the ... a controlled environment with a low level of pollutants. ... serve more IV nutrition consumers and better serve our ...
(Date:6/1/2017)... , June 1, 2017 Nutriceutical Holdings ... Veterinarian Recommended Solutions (VRS), and KD Pharma Group have ... Nutriceutical Holdings by KD Pharma Group. KD Pharma Group ... the option to acquire the entire company. ... KD. They are committed to growing the NH companies ...
(Date:5/26/2017)... , May 26, 2017  Endo International plc (NASDAQ: ... President and CEO, will represent the Company in a fireside ... Conference on Tuesday, June 13, 2017 at 10:40 a.m. PT ... Terranea Resort in Rancho Palos Verdes, CA. ... the event will be available on the Company,s website at ...
Breaking Medicine Technology: