Navigation Links
Gene Signature May Predict Recurrence of Lung Cancer
Date:5/16/2008

Could help docs determine who would benefit most from chemo after surgery, study says

FRIDAY, May 16 (HealthDay News) -- A panel of 15 genes may help determine which patients with early-stage non-small cell lung cancer will experience a recurrence and, therefore, benefit the most from chemotherapy, a new study shows.

By extension, the same genetic signature may also identify patients with less aggressive forms of the cancer who would be able to forego chemotherapy.

"Using this signature, we can identify up to 30 to 40 percent of stage I patients who might benefit from post-surgery chemotherapy and maybe up to 30 to 40 percent who might not benefit," said study author Dr. Ming Tsao, who will present the finding June 1 at the American Society of Clinical Oncology (ASCO) annual meeting, in Chicago. "The idea is that this could potentially supercede staging, although we definitely need more studies. [The information] is not immediately useful."

Previous trials have shown a benefit for stage I and II non-small cell lung cancer patients who received chemo after surgery. But, so far, the benefit has been confined mostly to stage II patients.

Even so, the distinction is not clear-cut. Some 30 percent of stage I patients who don't get added chemotherapy will die of a disease recurrence, and it's also possible that some stage II patients might not need chemotherapy after surgery.

"The goal of this study was to identify the genetic characteristics that could potentially be used to predict more precisely the likelihood of clinical outcomes, so those who need post-surgery chemo should get it and those who do not need it do not get it," explained Tsao, who is professor of laboratory medicine at the University of Toronto and a senior scientist at Princess Margaret Hospital in Toronto.

Gene expression profiling was performed on frozen tumor tissues from 64 patients as part of a follow-up analysis of
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. 24 Hour Fitness Partners With Derek Jeter to Launch Signature Sports Clubs in New York City
2. Chemical signature of manic depression discovered by scientists
3. Avamere Health Systems Announces New President of Signature Home Health
4. Emmy(R)- and Golden Globe(R)-Nominated Actress Marcia Cross and Lifetime Television Deliver 20 Million Online Petition Signatures to Capitol Hill to Urge Congress to Stop Drive-Through Mastectomies
5. Hays AG Integrates Authentidate(R) Signature Solution for Electronic Invoicing
6. New neuroimaging study identifies brain signature for cigarette cravings
7. APHA Urges President Bush Not To Veto CHIP; Were Only One Signature Away from Protecting the Health of Our Children
8. Gene signature spells poor outcome
9. Protein predicts Gleevec resistance in gastrointestinal tumors
10. Biomarkers Predict Heart Deaths
11. Study shows gene variations may predict risk of breast cancer in women
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Gene Signature May Predict Recurrence of Lung Cancer
(Date:8/20/2014)... easier to predict both breast cancer relapses and ... unique gene. The newly found marker could help ... a treatment regimen that is more effective. The ... A*STAR,s Institute of Molecular and Cell Biology (IMCB), ... Singapore) at the National University of Singapore (NUS). ...
(Date:8/20/2014)... It’s no secret that millions of Americans are ... on Drug Abuse, nearly 24 million Americans are using ... is the fact that the total number of users ... in a struggle with substance abuse often feel there ... newly-redesigned AbuseTreatmentCenters.net has released updated lists of substance ...
(Date:8/20/2014)... Mateo, CA (PRWEB) August 20, 2014 ... newest product—the Really Little Green Pouch —to meet ... to feed babies and toddlers homemade foods. , ... Little Green Pouch co-founder Maggie Crawford. She continues, ... kids, to limit exposure to things like pesticides and ...
(Date:8/20/2014)... Botanica Day Spa has ... new and popular stem cell line from Pevonia®, ... wrinkles and naturally repairs the skin. The spa ... service by offering clients a complimentary dermaplaning session ... , Pevonia® continues to be a global leader ...
(Date:8/20/2014)... car at home and getting to work by walking, cycling ... study indicates. Researchers looked at thousands of people in ... and 72 percent of women drove to work, 10 percent ... and 14 percent of men and 17 percent of women ... more and had higher levels of body fat than those ...
Breaking Medicine News(10 mins):Health News:Novel gene predicts both breast cancer relapse and response to chemotherapy 2Health News:Re-Launched AbuseTreatmentCenters.net Offering New List of Substance Abuse Resources 2Health News:Little Green Pouch Launches New Product to Help Health-conscious Parents Reduce Babies’ Eco-footprint 2Health News:New Stem Cell Facial Unveiled at Botanica Day Spa 2Health News:New Stem Cell Facial Unveiled at Botanica Day Spa 3Health News:Want to Stay Slim? Leave the Car at Home 2
... 7 (HealthDay News) -- In November, the U.S. Food and ... the treatment of breast cancer. But, a new study ... with a specific type of aggressive breast tumor when used ... (bevacizumab) had been approved in the United States in 2008 ...
... the fierce national debate over a new federal law ... widely assumed that private health insurance can do a ... U.S. government. But a first-of-its-kind analysis of newly ... comes to infants covered by insurance. Among the ...
... HealthDay Reporter , WEDNESDAY, Dec. 7 (HealthDay News) ... with low-risk prostate cancer, a new draft report released ... concluded that research on the safety of "active surveillance" ... men opt for surgery or other treatments that can ...
... have altered natural bioelectrical communication among cells to directly ... at a particular location within a vertebrate organism. Using ... biologists at Tufts University,s School of Arts and Sciences ... of the head area. The researchers achieved most ...
... California,s low-income seniors with disabilities are struggling to remain in ... and may be slashed even further, according to a new ... with support from The SCAN Foundation. Should ... to In-Home Supportive Services (IHSS) on Dec. 15, as proposed ...
... Amanda Gardner HealthDay Reporter , WEDNESDAY, Dec. 7 ... through strategically placed "seeds" had double the risk of a ... their entire breast, new research finds. This type ... side effects, including infection, according to the study. "We ...
Cached Medicine News:Health News:Avastin Boosted Survival for Type of Aggressive Breast Cancer: Study 2Health News:Public health insurance offers insured infants better, less costly care than private plans 2Health News:Public health insurance offers insured infants better, less costly care than private plans 3Health News:Public health insurance offers insured infants better, less costly care than private plans 4Health News:Public health insurance offers insured infants better, less costly care than private plans 5Health News:Active Surveillance May Benefit Men With Low-Risk Prostate Cancer 2Health News:Researchers discover that changes in bioelectric signals cause tadpoles to grow eyes in back, tail 2Health News:Researchers discover that changes in bioelectric signals cause tadpoles to grow eyes in back, tail 3Health News:Older Californians with disabilities struggle to remain at home as public programs lose funding 2Health News:Older Californians with disabilities struggle to remain at home as public programs lose funding 3Health News:Older Californians with disabilities struggle to remain at home as public programs lose funding 4Health News:Targeted Radiation May Not Be Better for Breast Cancer 2Health News:Targeted Radiation May Not Be Better for Breast Cancer 3
(Date:8/19/2014)...  The Alabama Supreme Court, in a 6-3 decision on ... who mislead doctors into believing that prescription medicines the companies ... v. Wyeth, and the decision came after the Supreme Court ... year. Heninger Garrison Davis attorneys Lew Garrison and ... Danny Weeks . The decision won a ...
(Date:8/19/2014)... , Aug. 19, 2014 Research and ... "Pharmaceutical Contract Manufacturing - Global Strategic Business Report" ... analyzes the worldwide markets for Pharmaceutical Contract Manufacturing in ... Vials, and IV solutions), Solid Dosage Forms (Tablets and ... Gels, Creams & Ointments). The report provides ...
(Date:8/19/2014)... 2014  AVIA – a provider-led accelerator that puts ... problems in healthcare ­– announces Sutter Health, a not-for-profit ... as the most recent addition to the AVIA Innovator ... AVIA,s inaugural cohort focused helping patients navigate the healthcare ... a patient,s providers so they work as a larger ...
Breaking Medicine Technology:Heninger Garrison Davis Clients To Get Their Day in Court Against Brand Drug Companies 2Heninger Garrison Davis Clients To Get Their Day in Court Against Brand Drug Companies 3Heninger Garrison Davis Clients To Get Their Day in Court Against Brand Drug Companies 4Global Pharmaceutical Contract Manufacturing - Strategic Business Report 2014 2AVIA and Sutter Health Join Forces to Address Healthcare's Most Pressing Challenges 2
... measurement technology, today announced the addition of the EmBand 24™ to the EmBand™ family of neuromarketing measurement devices. , ... , , ... ... ...
... , ATLANTA , March 22 Fulcrum Ventures announced today that they invested $1.25 ... solution for kit design, production, client supply management and patient specimen tracking.  Based in Columbus, Georgia , ... ... , ...
Cached Medicine Technology:EmSense Announces Release of Revolutionary EmBand 24(TM) 2EmSense Announces Release of Revolutionary EmBand 24(TM) 3EmSense Announces Release of Revolutionary EmBand 24(TM) 4Fulcrum Ventures Leads $1.25 Million Investment in Path-Tec, LLC 2Fulcrum Ventures Leads $1.25 Million Investment in Path-Tec, LLC 3