Navigation Links
Gene 'Signature' May Point to Lung Cancer
Date:12/1/2009

Discovery could aid in development of simple screening test, expert says

TUESDAY, Dec. 1 (HealthDay News) -- In a finding that could lead to a simple blood test to screen for lung cancer, U.S. researchers have identified immune system markers that indicate early-stage lung tumors in people at high risk for lung cancer.

The researchers examined gene expression profiles in blood samples from 137 people with non-small cell lung cancer and a control group of 91 people with non-malignant lung diseases, such as chronic obstructive pulmonary disease, emphysema or benign lung nodules.

They identified a 29-gene "signature" that was 86 percent accurate in identifying those with lung cancer, who had certain genetic changes in immune cells that the others did not.

Blood samples were taken from 18 of those with lung cancer before surgery to remove their tumors and two to five months after surgery. After surgery, 13 of them showed a decrease or disappearance of the tumor gene signature.

The study was published online Dec. 1 in Cancer Research.

The researchers said it might be possible to use the findings to develop a simple blood test to screen for lung cancer.

"People routinely get blood taken at their doctors' offices for cholesterol levels, diabetes and other standard tests, so why not utilize this method to screen for other conditions such as the risk of developing lung cancer?" Louise C. Showe, a professor in the molecular and cellular oncology and immunology programs and director of the genomics facility at the Wistar Institute in Philadelphia, said in a news release from the institute.

"Such a test could be especially useful for remote areas where, typically, technologies that are used in urban centers are not available," she said. "In addition, this test could be useful in a clinical setting to help to decide whether a small tumor detected on an X-ray is likely to be malignant."

More information

The U.S. National Cancer Institute has more about lung cancer screening.



-- Robert Preidt



SOURCE: Wistar Institute, news release, Dec. 1, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Therap Services to Host Conference on Electronic Documentation, Electronic Signatures and Electronic Health Records for the Developmental Disabilities Community
2. GlobalSubmit Extends Signature Partnership Program
3. American Laser Centers Wins Platinum, Gold Awards from SignatureForum
4. National Center for Policy Analysis and Salem Radio Network Deliver Million-Plus Signature Petition Opposing Government Run Health Care
5. San Francisco Home Care Workers Describe Lies, Coercion, and Fraud in Union Signature Drive
6. SignatureForum Reveals Top-Rated Cosmetic Surgeons in US
7. SignatureForum Reveals Top-Rated Aesthetic Medical Practices in U.S.
8. SAFE-BioPharma Webinar Featuring ARX's Digital Signatures Combined with Microsoft SharePoint for Bio-Pharma industry
9. SAFE-BioPharma Webinar Featuring ARX's Digital Signature Solution and Adobe LiveCycle Combined Solution
10. Gene signature may predict patient response to therapy for gastrointestinal stromal tumors
11. World-Renowned Neuroscientist Dr. Candace Pert will be Featured Speaker at the Chopra Center's Signature Mind-Body Healing Workshop in San Diego
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/23/2017)... ... January 23, 2017 , ... METTLER TOLEDO has announced ... by Applying Simple PAT Tools . , Crystallization is a common ... desired product. Chemists now spend more time developing better intermediate and final ...
(Date:1/23/2017)... ... January 23, 2017 , ... Steviva ... organic certification under the USDA National Organic Program (NOP) for its Portland SQF ... have established organic production and handling systems to complement our current rigorous food-safety ...
(Date:1/23/2017)... ... 23, 2017 , ... Old School Labs™, makers of the wildly popular all-natural ... Breon Ansley to its growing team of brand ambassadors. The Olympia top finisher and ... less than a year was able to turn professional, participating in the 2013 NPC ...
(Date:1/23/2017)... ... January 23, 2017 , ... Gynecology Associates of Gwinnett (GAoG) ... services for women of all ages. The staff of Gynecology Associates of ... services from routine health screenings to diagnosing and treating female concerns including menopause, ...
(Date:1/23/2017)... ... January 23, 2017 , ... “Crossing the Bar”: a moving and eloquent ... life. “Crossing the Bar” is the creation of published author, Charlotte Hotte, a North ... who credits the inspiration of the book to her sister, Denise, wishes to acknowledge ...
Breaking Medicine News(10 mins):
(Date:1/21/2017)... 2017 According to a new market research ... R&D, Compliance, SCM), Component (Software, Service), Delivery (On premise, Cloud), End ... by MarketsandMarkets, the market is expected to reach USD 24.73 Billion ... of 13.3% during the forecast period. ... ...
(Date:1/21/2017)...  Faruqi & Faruqi, LLP, a leading national securities law ... (NASDAQ: KMPH ) of the federal securities class ... directors and underwriters of the Company,s April 16, 2015 Initial ... plaintiff. The lawsuit has been filed in the ... Johnson County on behalf of all those who ...
(Date:1/20/2017)... , January 20, 2017 Stock-Callers.com today ... SGYP ), Novo Nordisk A/S (NYSE: ... and Pernix Therapeutics Holdings Inc. (NASDAQ: PTX ). ... Thursday, January 19 th , 2017, finishing near its session ... Index dropped over 0.7%, while shares of health care companies ...
Breaking Medicine Technology: