Navigation Links
Gene 'Signature' May Point to Lung Cancer
Date:12/1/2009

Discovery could aid in development of simple screening test, expert says

TUESDAY, Dec. 1 (HealthDay News) -- In a finding that could lead to a simple blood test to screen for lung cancer, U.S. researchers have identified immune system markers that indicate early-stage lung tumors in people at high risk for lung cancer.

The researchers examined gene expression profiles in blood samples from 137 people with non-small cell lung cancer and a control group of 91 people with non-malignant lung diseases, such as chronic obstructive pulmonary disease, emphysema or benign lung nodules.

They identified a 29-gene "signature" that was 86 percent accurate in identifying those with lung cancer, who had certain genetic changes in immune cells that the others did not.

Blood samples were taken from 18 of those with lung cancer before surgery to remove their tumors and two to five months after surgery. After surgery, 13 of them showed a decrease or disappearance of the tumor gene signature.

The study was published online Dec. 1 in Cancer Research.

The researchers said it might be possible to use the findings to develop a simple blood test to screen for lung cancer.

"People routinely get blood taken at their doctors' offices for cholesterol levels, diabetes and other standard tests, so why not utilize this method to screen for other conditions such as the risk of developing lung cancer?" Louise C. Showe, a professor in the molecular and cellular oncology and immunology programs and director of the genomics facility at the Wistar Institute in Philadelphia, said in a news release from the institute.

"Such a test could be especially useful for remote areas where, typically, technologies that are used in urban centers are not available," she said. "In addition, this test could be useful in a clinical setting to help to decide whether a small tumor detected on an X-ray is likely to be malignant."

More information

The U.S. National Cancer Institute has more about lung cancer screening.



-- Robert Preidt



SOURCE: Wistar Institute, news release, Dec. 1, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Therap Services to Host Conference on Electronic Documentation, Electronic Signatures and Electronic Health Records for the Developmental Disabilities Community
2. GlobalSubmit Extends Signature Partnership Program
3. American Laser Centers Wins Platinum, Gold Awards from SignatureForum
4. National Center for Policy Analysis and Salem Radio Network Deliver Million-Plus Signature Petition Opposing Government Run Health Care
5. San Francisco Home Care Workers Describe Lies, Coercion, and Fraud in Union Signature Drive
6. SignatureForum Reveals Top-Rated Cosmetic Surgeons in US
7. SignatureForum Reveals Top-Rated Aesthetic Medical Practices in U.S.
8. SAFE-BioPharma Webinar Featuring ARX's Digital Signatures Combined with Microsoft SharePoint for Bio-Pharma industry
9. SAFE-BioPharma Webinar Featuring ARX's Digital Signature Solution and Adobe LiveCycle Combined Solution
10. Gene signature may predict patient response to therapy for gastrointestinal stromal tumors
11. World-Renowned Neuroscientist Dr. Candace Pert will be Featured Speaker at the Chopra Center's Signature Mind-Body Healing Workshop in San Diego
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... , ... Conventional wisdom preaches the benefits of moderation, whether it’s a matter ... bar too high can result in disappointment, perhaps even self-loathing. However, those who set ... , Research from PsychTests.com reveals that behind the tendency to set low ...
(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, was out ... family verbally and physically. , “When something upset him, he couldn’t control his emotions,” remembers ... would throw rocks at my other children and say he was going to kill them. ...
(Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San Diego, CA is excited ... To Recovery® program to drive cancer patients to and from their cancer treatments. ... highest quality of life and ongoing independence. Getting to and from medical treatments ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Haute ... Dr. Barry M. Weintraub as a prominent plastic surgeon and the network’s newest ... world, and the most handsome men, look naturally attractive. Plastic surgery should be ...
(Date:6/24/2016)... Washington, D.C. (PRWEB) , ... June 24, 2016 , ... ... Pro-Am Heroes Golf Classic Tournament held on June 20th at the Woodmont Country ... local charity, Luke’s Wings, an organization dedicated to helping service members that have been ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... N.C. , June 24, 2016  Consumers ... decisions and regulators/payers have placed more emphasis on ... environment, patient support programs in the pharmaceutical industry ... patients, medications. Consequently, pharmaceutical companies are focusing on ... they are providing products and services that improve ...
(Date:6/24/2016)... DUBLIN , June 24, 2016 ... and Markets has announced the addition of the ... their offering. ... products and provides an updated review, including its applications ... covering the total market, which includes three main industries: ...
(Date:6/24/2016)... Mass. and SAN CLEMENTE, Calif. , ... California -based mobile pulmonary function testing company, is now able ... PFT devices developed by ndd Medical Technologies , Inc. ... testing done in hospital-based labs.  Thanks to ndd,s EasyOne PRO ® ... , can get any needed testing done in the comfort ...
Breaking Medicine Technology: