Navigation Links
Gene 'Signature' May Point to Lung Cancer
Date:12/1/2009

Discovery could aid in development of simple screening test, expert says

TUESDAY, Dec. 1 (HealthDay News) -- In a finding that could lead to a simple blood test to screen for lung cancer, U.S. researchers have identified immune system markers that indicate early-stage lung tumors in people at high risk for lung cancer.

The researchers examined gene expression profiles in blood samples from 137 people with non-small cell lung cancer and a control group of 91 people with non-malignant lung diseases, such as chronic obstructive pulmonary disease, emphysema or benign lung nodules.

They identified a 29-gene "signature" that was 86 percent accurate in identifying those with lung cancer, who had certain genetic changes in immune cells that the others did not.

Blood samples were taken from 18 of those with lung cancer before surgery to remove their tumors and two to five months after surgery. After surgery, 13 of them showed a decrease or disappearance of the tumor gene signature.

The study was published online Dec. 1 in Cancer Research.

The researchers said it might be possible to use the findings to develop a simple blood test to screen for lung cancer.

"People routinely get blood taken at their doctors' offices for cholesterol levels, diabetes and other standard tests, so why not utilize this method to screen for other conditions such as the risk of developing lung cancer?" Louise C. Showe, a professor in the molecular and cellular oncology and immunology programs and director of the genomics facility at the Wistar Institute in Philadelphia, said in a news release from the institute.

"Such a test could be especially useful for remote areas where, typically, technologies that are used in urban centers are not available," she said. "In addition, this test could be useful in a clinical setting to help to decide whether a small tumor detected on an X-ray is likely to be malignant."

More information

The U.S. National Cancer Institute has more about lung cancer screening.



-- Robert Preidt



SOURCE: Wistar Institute, news release, Dec. 1, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Therap Services to Host Conference on Electronic Documentation, Electronic Signatures and Electronic Health Records for the Developmental Disabilities Community
2. GlobalSubmit Extends Signature Partnership Program
3. American Laser Centers Wins Platinum, Gold Awards from SignatureForum
4. National Center for Policy Analysis and Salem Radio Network Deliver Million-Plus Signature Petition Opposing Government Run Health Care
5. San Francisco Home Care Workers Describe Lies, Coercion, and Fraud in Union Signature Drive
6. SignatureForum Reveals Top-Rated Cosmetic Surgeons in US
7. SignatureForum Reveals Top-Rated Aesthetic Medical Practices in U.S.
8. SAFE-BioPharma Webinar Featuring ARX's Digital Signatures Combined with Microsoft SharePoint for Bio-Pharma industry
9. SAFE-BioPharma Webinar Featuring ARX's Digital Signature Solution and Adobe LiveCycle Combined Solution
10. Gene signature may predict patient response to therapy for gastrointestinal stromal tumors
11. World-Renowned Neuroscientist Dr. Candace Pert will be Featured Speaker at the Chopra Center's Signature Mind-Body Healing Workshop in San Diego
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/19/2017)... ... February 19, 2017 , ... Orbita, Inc., a ... with Healthwise ® at HIMSS 2017 to showcase a breakthrough ... health education, technology and services, will demonstrate a voice-powered knowedge assistant based on ...
(Date:2/18/2017)... ... February 17, 2017 , ... Butler Mobility invited Ken Matthews to visit ... Butler products. Ken was impressed with the safety and reliability of the Stannah ... on his show. This endorsement by Ken Matthews can be heard on News ...
(Date:2/18/2017)... ... February 18, 2017 , ... ProParagraph Fashion Volume 2 features ... ProParagraph Fashion Volume 2 for all multi-line FCPX project needs. Great for ... and choose from hand-crafted trend-setting designs with smooth animations that will add stylistic ...
(Date:2/17/2017)... ... February 17, 2017 , ... While EHR data ... has introduced an innovative workstation designed to reduce nursing fatigue while enhancing productivity. ... EHR Workstation offers a lightweight, highly mobile, multi-functional alternative to the limitations of ...
(Date:2/17/2017)... ... February 17, 2017 , ... For the first time, International ... the exhibit floor for the 2017 HIMSS Conference & Exhibition at ... 2017, more than 40,000 healthcare industry professionals are expected at the conference, where ...
Breaking Medicine News(10 mins):
(Date:2/19/2017)... Fla. , Feb. 19, 2017  nThrive™, ... revenue cycle portfolio and thought leadership at the ... receiving a category leader award from KLAS. ... panel discussion focused on how market trends shape ... -  particularly a sophisticated, comprehensive Patient Access solution. ...
(Date:2/18/2017)... , Feb. 17, 2017   Parker ... protecting the rights of victims injured by medical ... regulators to call for better reporting. Congress required ... Safety concerns involving power morcellators and duodenoscopes ... to investigate how hospitals report injuries and deaths ...
(Date:2/17/2017)... Cryoablation, Electrical, Endometrial Hydrothermal, Laser/Light, Microwave, Radiofrequency, Ultrasound, Cardiovascular, ... is expected to grow at a CAGR of 9.4% from 2017-2022 ... grow at a CAGR of 9.5% from 2017 to 2027. The ... ... will benefit you Read on to discover how you can ...
Breaking Medicine Technology: