Navigation Links
Gene Screen Might Predict Prostate Cancer
Date:11/17/2008

Such a test would be especially useful for blacks, other high-risk groups

MONDAY, Nov. 17 (HealthDay News) -- Doctors may someday be able to use five genetic markers to assess whether a man is at high risk to develop prostate cancer, a new study suggests.

If reliable, these five "single nucleotide polymorphisms" (SNPs) would be especially important for black patients, or men of any race with a family history of prostate cancer. These two groups have a twofold to sevenfold increased chance of developing the disease, experts note.

The research is scheduled to be presented Monday at the American Association for Cancer Research's annual conference on cancer prevention in Washington, D.C.

"There have been years of effort to try to identify genes and genetic mutations associated with prostate cancer, as there are [such genes] for breast cancer," Dr. Veda N. Giri, director of the Prostate Cancer Risk Assessment Program (PRAP) at Fox Chase Cancer Center, in Philadelphia, explained in a news release issued by the conference organizers. "Prostate cancer is a more genetically complex disease."

The study included 700 men with either one first-degree relative with prostate cancer or two second-degree relatives with prostate cancer on the same side of the family. Giri and colleagues said they found similarities in these five genetic markers among high-risk white men and those already diagnosed with prostate cancer. The findings were even more profound among black men.

"When we compared African-American men in PRAP to the high-risk Caucasian men in PRAP, we did find a difference," she said. "African-American men tended to carry more of these genetic risk markers compared to the Caucasian men. Since African-American men carry more of these particular genetic markers, they may be more informative for prostate cancer risk assessment in African-American men."

The researchers also found a trend that black men who carried more of these risk markers tended to develop prostate cancer earlier, Giri said, however, the finding was not statistically significant.

"These markers may have significant use in personalizing the early detection of prostate cancer in men at high risk in order to provide tailored recommendations for screening and diagnosis of this disease," Giri said.

More information

The U.S. National Cancer Institute has more about prostate cancer.



-- Kevin McKeever



SOURCE: American Association for Cancer Research, news release, Nov. 17, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. FDA Proposes New Rules for Sunscreens
2. Frequent Prostate Screens Fail to Improve Aggressive Cancer Diagnoses
3. FDA Approves New Roche West Nile Virus Blood Screening Test
4. Physician Skin Care Specialist Says Proposed New Rules for Sunscreen Products Will Better Protect the Public
5. New lung cancer guidelines oppose general CT screening
6. New Lung Cancer Guidelines Oppose General CT Screening
7. Lung Cancer Alliance Stands Behind CT Screening for Lung Cancer
8. Prostate Cancer Awareness Week to Screen Thousands
9. Screening Proposed for Childhood Cholesterol Levels
10. A new technology for cancer screening listens for the signs of cancer
11. Study Questions Genetic Screening for Treatable Diseases
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Gene Screen Might Predict Prostate Cancer
(Date:6/24/2016)... ... , ... June 19, 2016 is World Sickle Cell Observance Day. In an ... of holistic treatments, Serenity Recovery Center of Marne, Michigan, has issued a ... Cell Disease (SCD) is a disorder of the red blood cells, which can cause ...
(Date:6/24/2016)... ... 2016 , ... The Pulmonary Hypertension Association (PHA) learned during ... two significant new grants to support its work to advance research and patient ... recognizing patients, medical professionals and scientists for their work in fighting pulmonary hypertension ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... now offering micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive experience with ... Damon brackets , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a ...
(Date:6/24/2016)... ... ... BioMedics, Inc, makers of Topricin and MyPainAway Pain Relief Products, join The ‘Business for a ... an hour by 2020 and then adjusting it yearly to increase at the same rate ... assure the wage floor does not erode again, and make future increases more predictable. , ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... the Clinical Decision Making in Emergency Medicine conference in Ponte Vedra Beach, FL. ... articles published in Emergency Medicine Practice and Pediatric Emergency Medicine Practice. ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 2016 Bracket , a leading clinical trial ... clinical outcomes platform, Bracket eCOA (SM) 6.0, at the ... – 30, 2016 in Philadelphia , Pennsylvania.  ... Assessment product of its kind to fully integrate with RTSM, ... eCOA 6.0 is a flexible platform for electronic clinical outcomes ...
(Date:6/23/2016)...  Astellas today announced the establishment of Astellas Farma Colombia (AFC), a new affiliate with operations headquartered in ... . ... ... ... Astellas ...
(Date:6/23/2016)... , June 23, 2016 The vast ... an outpatient dialysis facility.  Treatments are usually 3 times ... hours per visit, including travel time, equipment preparation and ... patient, but especially grueling for patients who are elderly ... a skilled nursing and rehabilitation centers for some duration ...
Breaking Medicine Technology: