Navigation Links
Gene Research Sheds Light on Lung Cancer Survival Time
Date:12/15/2010

WEDNESDAY, Dec. 15 (HealthDay News) -- Genes that predict length of survival and help guide treatment for patients with non-small cell lung cancer have been identified by U.S. researchers.

The investigators took samples of lung tumors and nearby healthy lung tissue from 30 patients and examined the samples for the presence of messenger ribonucleic acid (mRNA) associated with 48 known genes for molecules called nuclear hormone receptors.

They then compared the active genes with patient outcomes and found that the expression of genes for certain nuclear hormone receptors helped predict patient survival.

According to the results, patients with two specific nuclear hormone receptors in their tumor tissue lived the longest. The two "biomarkers" were the short heterodimer partner and the progesterone receptor.

"Patient responses to cancer treatment vary widely and often depend on subtle biological differences among tumors," study co-lead author Dr. David Mangelsdorf, chairman of pharmacology at the University of Texas Southwestern Medical Center, said in a facility news release.

"These findings are important because the ability to determine which genes are being expressed in each person's tumor, as well as a patient's likely survival time, can guide physicians to the most effective and appropriate personalized treatments," he added.

The study was published in the Dec. 14 edition of the journal PLoS Medicine.

More information

The American Cancer Society has more about non-small cell lung cancer.

-- Robert Preidt

SOURCE: University of Texas Southwestern Medical Center, news release, Dec. 14, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Breast inflammation is key to cancer growth, Kimmel Cancer Center researchers say
2. Genetic Research Sheds Light on Adrenal Gland Tumor Risk
3. Researchers discover new signaling pathway linked to inflammatory disease
4. UCI researchers find novel memory-enhancing mechanism in brain
5. Cancer Research Institute launches Cancer Vaccine Acceleration Fund
6. States Now Fund Most Embryonic Stem Cell Research in U.S.
7. Researchers make critical leukemia stem cell discovery
8. U-M researchers discover way to block neurodegeneration in an adult form of Fragile X syndrome
9. Leibniz Prize 2011: 10 researchers awarded €2.5 million ($3.3 million) each
10. Research tackles drug use, HIV in South African youth
11. Researchers Turn Stem Cells Into Intestinal Tissue in Lab
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Gene Research Sheds Light on Lung Cancer Survival Time
(Date:10/13/2017)... N.J. (PRWEB) , ... October 13, 2017 , ... The ... Holly Day Market. Featuring a collection of specialty vendors and unique items from across ... personalized and quality-focused health and wellness services offered by the VNA. The boutique ...
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, a ... has been awarded a contract by the Center for Medicare and Medicaid Services ... accelerate the enterprise use of Agile methodologies in a consistent and high value ...
(Date:10/12/2017)... ... ... Planet Fitness, one of the largest and fastest growing franchisors and operators ... location in Covington, LA at 401 N. U.S. Highway 190, in January of 2018. ... in the Holiday Square shopping center. Its location allows it to serve both Covington ...
(Date:10/12/2017)... Maryland (PRWEB) , ... October 12, 2017 , ... ... magnetic drug delivery system that we intend to develop to enable prevention of ... can lead to severe hearing loss, especially in pediatric patients. For cisplatin, hearing ...
(Date:10/12/2017)... ... 12, 2017 , ... Women-owned and Grand Rapids-based workplace wellness ... in Wellness® by Best and Brightest. OnSite Wellness will be honored at the ... 7:30 a.m. to 2 p.m. at the Henry Autograph Collection Hotel, located at ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... 11, 2017  BioPharmX Corporation (NYSE MKT: BPMX) researchers ... an innovative way to use nonlinear optical imaging to ... new drugs. ... will show how researchers from BioPharmX and the Wellman ... used a suite of imaging techniques in what is ...
(Date:10/10/2017)... Oct. 10, 2017   West Pharmaceutical Services, Inc. ... for injectable drug administration, today shared the results of ... for improving the intradermal administration of polio vaccines. The ... Summit in May 2017 by Dr. Ondrej Mach ... World Health Organization (WHO), and recently published in the ...
(Date:10/4/2017)... Oct. 4, 2017 OBP Medical ... illuminating medical devices, today announced regulatory approval from ... Agency (or Agência Nacional de Vigilância Sanitária (ANVISA)) ... cordless surgical retractor with integrated LED light source ... illumination and exposure of a tissue pocket or ...
Breaking Medicine Technology: