Gene Network Sciences Announces Brain Cancer Collaboration With M.D...( CAMBRIDGE Mass. April 14 /- Gene Netw...),Health

CAMBRIDGE, Mass., April 14 /PRNewswire/ -- Gene Network Sciences, Inc. (GNS) today announced that it has entered into a research collaboration with The University of Texas M.D. Anderson Cancer Center aimed at the rapid translation of DNA sequence and clinical data from patients with glioblastoma, the most common and deadly form of brain cancer, into breakthrough discoveries leading to drugs and diagnostics. This collaboration will leverage the combination of groundbreaking genetic data and clinical oncology expertise from M.D. Anderson with supercomputers and advanced machine-learning software from GNS. Financial terms of the agreement were not disclosed.

The rich glioblastoma dataset produced by M.D. Anderson researchers, which includes genetic, genomic, and clinical endpoint data ("3-D Data"), will be analyzed using GNS's supercomputer-driven REFS(TM) (Reverse Engineering and Forward Simulation) software platform. These analyses are expected to generate models that enable the discovery of key genes, proteins and other molecular entities that together, as a network, causally drive glioblastoma disease progression, disease recurrence, and survival. The results from these projects will include the identification of new combination drug targets for disease and the development of diagnostics to determine appropriate individual patient treatments.

"There continues to be an urgent need for a more efficient translation of research into improved treatments for glioblastoma patients," said Dr. Kenneth Aldape, who led the M.D. Anderson glioblastoma research team that conducted the research that produced the data. "With its computational expertise and commercially tested REFS(TM) platform, GNS is well positioned to work with us to achieve the desired acceleration in the development of sorely needed effective treatments and diagnostics for this deadly disease."

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