Navigation Links
Gene Mutations for Rare Heart Disease Also Found in Kids
Date:4/9/2008

Test for adults with muscle-thickening disorder may also identify children at risk

WEDNESDAY, April 9 (HealthDay News) -- The same 10 gene mutations responsible for cardiac hypertrophy (thickening of the heart muscle) in adults are also associated with many cases of this rare but life-threatening condition in children, says a U.S. study.

The mutations even showed up in children who had no family history of the condition, the researchers noted.

Currently, little is known about the causes of cardiac hypertrophy in children, so no diagnostic tests for children have been developed. The findings of this study suggest that the same genetic test designed for adults can be used in children, which may help increase knowledge about the condition and lead to new kinds of treatments, said study authors Christine and Jonathan Seidman, professors at Harvard Medical School in Boston.

About one in 100,000 children develops cardiac hypertrophy, which can lead to sudden death. About 3 percent to 4 percent of adults have the condition. Most of the genes implicated in cardiac hypertrophy encode sarcomere proteins, which help the heart tighten and relax to pump blood.

"Cardiac hypertrophy increases your risk of all types of negative cardiovascular outcomes, including heart failure and sudden death. Although the condition is rare in children, the prognosis is even worse. Kids with cardiac hypertrophy are often candidates for transplantation," Jonathan Seidman said in a prepared statement.

"Labs have done work on the genetic underpinnings of cardiac hypertrophy in adults, but few thought that the research applied to children. For years, doctors assumed the two conditions were clinically distinct," Christine Seidman, who is also a member of the HMS-Partners HealthCare Center for Genetics and Genomics, said in a prepared statement.

In this study, the Seidmans and their colleagues from Children's Hospital Bos
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved

0

GOOD

Page: 1 2

Related medicine news :

1. Einstein researchers discover gene mutations linked to longer lifespans
2. 2 Mutations Were Critical to Spread of 1918 Flu
3. Benefit of cancer prevention surgery differs between women with BRCA1 and BRCA2 mutations
4. Scientists explore factors contributing to DNA mutations
5. Genetic Mutations Boost Prostate Cancer Risk
6. BRCA Mutations Dont Raise Breast Cancer Risk Equally
7. Ashkenazi ovarian cancer patients with BRCA mutations live longer than those with normal gene
8. Gene Mutations May Cause Rare Neonatal Diabetes
9. United Heartland Group Program Earns Record Dividend
10. Heart stem cell scientist to honor pioneering woman scientist in keynote speech
11. Psychologist develops post-operative care for heart patients in Bermuda
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/25/2013)... California (PRWEB) May 25, 2013 According to ... titled “Hooked on a Feeling,” nearly 30 million Americans tan ... to tan despite knowing the health risks. ... seductive and even addictive effect on the brains of some ... included in the article so I can’t say that I ...
(Date:5/25/2013)... Newport Beach, California (PRWEB) May 25, 2013 ... weekend respectfully honoring those who have died serving our ... from work with prolonged partying and recklessness. The DUI ... Memorial Day Weekend DUI checklist to help keep this ... California’s Traffic Records System , there were more than ...
(Date:5/25/2013)... 25, 2013 Dr. Leslie Gerstman ... FDA-approved to lift skin on the neck, on the brow ... practice, Medical Aesthetics. , Ultherapy is a non-surgical procedure for ... healing process to lift the skin over time. The use ... to see and then treat the deepest support layers of ...
(Date:5/25/2013)... 25, 2013 Life science and analytical ... to detect and create a new substance with the ... are also known as biotechnology reagents. Such reagents are ... education. , This market is driven by factors such ... field of therapeutics, growth in research and rapid commercialization ...
(Date:5/25/2013)... Boise, Idaho (PRWEB) May 25, 2013 ... most prevalent type of peripheral neuropathy. According to neuropathy ... http://goo.gl/aLMtn , it is estimated that the disorder affects ... most common complication arising from Diabetes. The high blood ... of Diabetes and patients suffering from it usually tend ...
Breaking Medicine News(10 mins):Health News:Sun Damage – Are UV Rays Addictive? 2Health News:Criminal Attorneys Provide Memorial Day Weekend DUI Checklist and Safety Information 2Health News:Criminal Attorneys Provide Memorial Day Weekend DUI Checklist and Safety Information 3Health News:Dr. Leslie Gerstman Is Now Offering the Non-surgical Facelifting Procedure – Ultherapy – in NYC and NJ 2Health News:Life Sciences And Analytical Reagents Market - New Industry Research Report is Now Available for Pre-Order at Transparency Market Research 2Health News:Life Sciences And Analytical Reagents Market - New Industry Research Report is Now Available for Pre-Order at Transparency Market Research 3Health News:Diabetic Neuropathy treatment hits new grounds- Neuracel launches the complete natural treatment 2
... Company Gifts of over $50 to,Doctors, ALBANY, ... Assembly Health Committee reported key legislation (see vote ... and sold in New York,State. Governor Paterson,s bill, ... ban on gifts of over $50 to doctors ...
... More than two million free antibiotic prescriptions ... Supercenter retailer Meijer,has announced plans to offer free ... The announcement was made today by Nat Love,Vice President ... "As a family-focused company, offering free pre-natal vitamins ...
... Rally Residents to Eat Right, Move More and Milk ... Their ... by,the ups and downs of different fad diets -- which seem to go ... been,slim. Two out of three Americans -- including 51 percent of Boise residents,-- ...
... State officials desire quick-response emergency capability to treat ... suspected and known cyanide ... L.P. today announced that the,Florida Department of Health, Office ... ANTIDOTE for Cyanide,Poisoning in the State,s emergency medical service ...
... age and ethnicity has a significant impact on overall ... led by researchers at the University of Southern California ... , While age and ethnicity are well-established factors that ... gender also plays an important role in overall survival, ...
... makes ovaries lose their ability to produce estrogens and ... this stage, when menstruation cesses, there appear physical and ... articulation and bone pain, headaches, insomnia, sadness, depression and ... the average age for the cessation of the menstrual ...
Cached Medicine News:Health News:Assembly on the Move for Rx Reform 2Health News:Assembly on the Move for Rx Reform 3Health News:Meijer Pharmacies to Offer Free Pre-Natal Vitamins 2Health News:Message to Idaho Residents: Forgo Fad Dieting and Join the Campaign for Healthy Weight 2Health News:Message to Idaho Residents: Forgo Fad Dieting and Join the Campaign for Healthy Weight 3Health News:Florida EMS and Fire Vehicles to Stock Cyanokit(R) 5g (hydroxocobalamin for injection) ANTIDOTE ("Cyanokit") for Cyanide Poisoning 2Health News:Florida EMS and Fire Vehicles to Stock Cyanokit(R) 5g (hydroxocobalamin for injection) ANTIDOTE ("Cyanokit") for Cyanide Poisoning 3Health News:USC study finds sex, age and ethnicity assciated with colorectal cancer survival 2Health News:Post-menopausal therapy to improve women's quality of life 2
(Date:5/23/2013)... , May 23, 2013  Hadasit Bio-Holdings Ltd. ... of biotech companies, based on intellectual property developed ... Israel ,s foremost medical research center, today ... Ltd., received significant funding from the Israeli Ministry ... Scientist (OCS) to support product development and advance ...
(Date:5/23/2013)... 2013 Anthem Blue Cross patients with HIV/AIDS ... them to obtain their medications by mail order under ... Kallas LLC.  The lawsuit, filed in ... Cross,s mandatory mail order program announced late last year ... "This settlement brings to a close a ...
(Date:5/23/2013)... Mass. , May 23, 2013  Hologic, ... HOLX ), a leading developer, manufacturer and supplier ... products, with an emphasis on serving the healthcare ... large-scale observational study in a U.S. clinical practice ... technology (breast tomosynthesis) with conventional 2D mammography alone ...
Breaking Medicine Technology:Hadasit Bio-Holdings Ltd. Portfolio Company - Cell Cure Neurosciences Ltd. Received Additional Government Support 2Blue Cross To Allow HIV/AIDS Patients to "Opt-Out" of Mandatory Mail-Order Rx Drug Program, Announces Consumer Watchdog 2Blue Cross To Allow HIV/AIDS Patients to "Opt-Out" of Mandatory Mail-Order Rx Drug Program, Announces Consumer Watchdog 3First Large-Scale Population-Based Study in the U.S. Shows Hologic's 3D Mammography (Breast Tomosynthesis) Significantly Reduces Recall Rates While Simultaneously Improving Cancer Detection 2First Large-Scale Population-Based Study in the U.S. Shows Hologic's 3D Mammography (Breast Tomosynthesis) Significantly Reduces Recall Rates While Simultaneously Improving Cancer Detection 3First Large-Scale Population-Based Study in the U.S. Shows Hologic's 3D Mammography (Breast Tomosynthesis) Significantly Reduces Recall Rates While Simultaneously Improving Cancer Detection 4
... 29 FUJIFILM Medical Systems USA, Inc. is pleased to ... at the 2009 Radiological Society of North America (RSNA) Annual ... an innovative new technology to provide clinicians with Fujifilm,s trademark ... a smart way for users to transition to DR without ...
... Nov. 28 Siemens Healthcare redefines productivity with a ... technology and with its new Dot(TM) (Day optimizing throughput) engine. ... Aera* 1.5 Tesla (T) and the new MAGNETOM Skyra* 3T ... the Radiological Society of North America (RSNA) from November 29 ...
Cached Medicine Technology:FUJIFILM's DR Cassette Makes World Debut 2Siemens Introduces Its New Power Couple at RSNA 2009 2Siemens Introduces Its New Power Couple at RSNA 2009 3Siemens Introduces Its New Power Couple at RSNA 2009 4Siemens Introduces Its New Power Couple at RSNA 2009 5Siemens Introduces Its New Power Couple at RSNA 2009 6Siemens Introduces Its New Power Couple at RSNA 2009 7
... Proteomeworks system is an integrated ... that enables protein function discovery. ... preparation, 2-D electrophoresis, staining, imaging ... automated protein digestion, mass spectrometry, ...
Storage temperature: 2 - 8C, linearity: 0 - 700 mg/dL, expected values: 30 - 780 mg/dL. Available with calibrator and number of tests 110....
Alkaline phosphatase FS (IFCC). For determination of alkaline phosphatase (ALP) in serum or plasma. For Hitachi 717. Controls: Trulab N and Trulab P....
For the quantitative determination of Alkaline Phosphatase in serum. Linearity: 800 IU/L at 37C. P-nitrophenyl phosphate substrate....
Medicine Products: