Navigation Links
Gene Mutation Tied to Inherited Fatal Lung Disease
Date:12/30/2008

Those with variant had cancer as well as idiopathic pulmonary fibrosis, study finds

TUESDAY, Dec. 30 (HealthDay News) -- A mutation in a gene previously found to help protect the lungs against toxins may also be linked to lung cancer and some inherited cases of a lethal lung disease affecting older adults, a new study says.

Mutations in the SFTPA2 gene have been found in families with the inherited version of idiopathic pulmonary fibrosis, or IPF -- a disease that affects about 200,000 people in the United States. The disease usually affects people age 50 and older, causing severe scarring of the lungs that results in about 40,000 deaths annually, according to the Pulmonary Fibrosis Foundation. About one in 50 people with IPF have an inherited form of the disease, for which there is no cure beyond a lung transplant.

The findings were published in the January issue of The American Journal of Human Genetics.

The SFTPA2 gene normally produces the surfactant protein A2 in the fluid of the lungs, and it helps protect the organ from invading pathogens.

In the study, in which University of Texas Southwestern researchers looked at people with the inherited form of the disease, many of those with the mutation had lung cancer as well as IPF. The researchers suspect the mutations are tied to both.

The research team is now working on molecular studies to find out why these gene mutations increase the risk for lung cancer or IPF.

More information

The National Heart, Lung, and Blood Institute has more about idiopathic pulmonary fibrosis.



-- Kevin McKeever



SOURCE: University of Texas Southwestern Medical Center at Dallas, news release, Dec. 19, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Gene Mutations May Cause Rare Neonatal Diabetes
2. Gene Mutation Linked to Parkinsons Disease
3. Research shows how genetic mutation causes epilepsy in infants
4. Gene Mutation Key to Infertility in Male Mice
5. Overlooked Mutation Can Spur HIV Drug Resistance
6. OHSU Cancer Institute researcher discovers what fuels certain cancer mutation
7. Breast cancer gene mutation more common in Hispanic, young black women, Stanford/NCCC study finds
8. BRCA1 Mutation Prevalent Among Hispanic, Younger Black Women
9. Ashkenazi ovarian cancer patients with BRCA mutations live longer than those with normal gene
10. BRCA Mutations Dont Raise Breast Cancer Risk Equally
11. Genetic Mutations Boost Prostate Cancer Risk
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Gene Mutation Tied to Inherited Fatal Lung Disease
(Date:10/13/2017)... Vegas, Nevada (PRWEB) , ... October 13, 2017 , ... ... 7® Hemp CBD Oil utilizing Purzorb™ technology. Applying the Purzorb™process to full spectrum CBD ... dose required and providing a CBD form that can be easily incorporated into liquid ...
(Date:10/13/2017)... ... October 13, 2017 , ... Lori R. Somekh, founder ... of ElderCounsel, a national organization of elder law and special needs planning attorneys. “Membership ... rules. It also provides a forum to network with elder law attorneys nationwide,” said ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Many families have ... many long-term care insurance companies have a waiver for care if the client has ... period, when the family pays for care, is often waived, so the benefits from ...
(Date:10/13/2017)... York, NY (PRWEB) , ... October 13, 2017 , ... ... influential people in business to advocate for action towards gender equality at their inaugural ... views from around the globe, and reached a social audience of over 3 million. ...
(Date:10/13/2017)... ... October 13, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The ... the most popular and least understood books in the Holy Scriptures, Revelation. The Book ... have baffled scholars for centuries. Many have tossed it off as mere rubbish, but ...
Breaking Medicine News(10 mins):
(Date:9/22/2017)... Md. , Sept. 22, 2017  As the ... Republican Senators Bill Cassidy (R-LA) and ... Information notes that the medical device industry is in ... medical device tax, the 2.3% excise tax on medical ... But they also want covered patients, increased visits and ...
(Date:9/18/2017)... ALLENTOWN , Pa. and KALAMAZOO, Mich. ... Allentown, Penn. , and OptiMed Specialty Pharmacy ... a business partnership to offer a strategic hub service ... PMD Healthcare,s highly sought-after personal spirometer, Spiro PD 2.0, ... A spirometer is a medical device used ...
(Date:9/12/2017)... , Sept. 12, 2017  Consumer reviews on the independent ... as the number one company for hearing aids, ranking it ... fifteen other brands. ... Hearing Named #1 by Consumers For Hearing Aids ... Embrace Hearing is an online store that provides high performance, ...
Breaking Medicine Technology: