Navigation Links
Gene Mutation Tied to Inherited Atrial Fibrillation
Date:7/9/2008

Defective hormone may point to new targets for treatment, study says

WEDNESDAY, July 9 (HealthDay News) -- A gene mutation linked to one family's hereditary form of atrial fibrillation may help researchers find better ways to predict, prevent and treat the heart rhythm problem, according to a new report.

The mutation -- a flaw in the DNA sequence -- was discovered by Mayo Clinic researchers studying a large family with an inherited form of atrial fibrillation in 11 relatives. Collaborators at the University of Iowa later confirmed the mutation's role in altering the electrical properties of the heart through an animal model.

The findings are published in the July 10 online version of the New England Journal of Medicine.

More than 2 million Americans have atrial fibrillation, the most common type of irregular heartbeat. It happens when the heart's two upper chambers beat irregularly and out of synch with the two lower chambers. This causes irregular, often rapid heart rates and can lead to inadequate blood flow to the body, putting the person at an increased risk of stroke. The condition can be treated with medications or surgery.

While risk factors for developing atrial fibrillation, such as high blood pressure or structural heart disease, are known, they are not always present.

"We know that some patients develop atrial fibrillation at a younger age without an apparent underlying cause, suggesting a hereditary basis for their disease and prompting research to identify gene mutations," senior study author Dr. Timothy Olson, a pediatric cardiologist at the Mayo Clinic, said in a news release issued by the facility.

Investigators gathered and analyzed clinical and genetic data from the 11 affected and five unaffected family members. All 11 with atrial fibrillation shared a mutation in the gene that codes for atrial natriuretic peptide (ANP), a hormone that helps regulate body
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved

Page: 1 2

Related medicine news :

1. Migraine mutations reveal clues to biological basis of disorder
2. Caris Diagnostics Providing KRAS Mutational Analysis for Colon Cancer Patients
3. New research on mutation in yeast can enhance understanding of human diseases
4. Gene mutation improves leukemia drugs effect
5. Specific mutations in the IL2RA gene associated with juvenile idiopathic arthritis
6. Discovery of new family of genetic mutations involved in inflammatory intestinal disease
7. Genetic mutation linked to walking on all 4s
8. Researchers Develop Stem Line With Sickle Cell Mutation
9. Research program focuses on genetic mutations and cancer risk
10. BRCA Mutations Dont Spot All High-Risk Women
11. Second breast cancer may be greater than thought for high-risk women without BRCA mutations
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... 2015 LunaDress, with its top dressmaking technologies, ... Now, the business is showing its latest designs of wedding ... According to the company’s CEO, all the fresh new products ... big discounts, up to 80% off. All the clothes from ...
(Date:1/22/2015)... 2015 VogueQueen is a seasoned and trusted ... many designers are thrilled to have it lead the wedding ... new collection of prom dresses for the global market. , ... strategic vision and he focuses on continuing the goal of ...
(Date:1/22/2015)... The federal court overseeing thousands of vaginal ... Southern District of West Virginia has upheld a $2 million ... bellwether trial. In an Order dated January 21st, the Court ... that C.R. Bard had not proven a miscarriage of justice. ...
(Date:1/22/2015)... For over 20 years, Dr. David Cruz of ... area has treated just about every type of injury that can ... for those same twenty-plus years, the team at Doctors on ... the best possible doctor. With the combined breadth of ...
(Date:1/22/2015)... 23, 2015 Recently, Weddingshe.com has added many ... has announced its highest annual revenues in the past three ... popular glamorous wedding dresses. , According to the sales manager ... dress promotions for them in 2015. This point can be ...
Breaking Medicine News(10 mins):Health News:LunaDress Shows The Latest Styles Of Wedding Dresses In 2015 2Health News:VogueQueen Unveils New Designs of Prom Dresses for 2015 2Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 2Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 3Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 4Health News:Industry Leading Chiropractor in Oceanside Joins the Doctors on Liens Network 2Health News:Weddingshe Announces A Special Offer On Its Popular Glamorous Wedding Dresses 2
... , MONDAY, Jan. 24 (HealthDay News) -- A brief, ... insomnia, a new study shows. The research involved 79 ... were divided into two groups. The 39 patients in the ... a nurse clinician. Two sessions were conducted in person and ...
... (HealthDay News) -- Continual exposure to stress prompts neural activity ... vigilance and emotion, a new study suggests. The finding ... recently deployed to Afghanistan, and is reported in the Jan. ... "For the first time we can now conclude that the ...
... Reporter , MONDAY, Jan. 24 (HealthDay News) -- The anti-estrogen ... ago may also reduce the risk of dying from lung ... Jan. 24 online edition of the journal Cancer , ... women who already had breast cancer. However, the results ...
... latest issues on the early detection of lung cancer, ... an international research consortium in Scottsdale, Ariz., Feb. 25-26. ... I-ELCAP, is a lung cancer research organization with participation ... states and eight other countries whose mission is to ...
... new study has found that tamoxifen, an anti-estrogen breast cancer ... cancer. Published early online in Cancer , a peer-reviewed ... hypothesis that there is a hormonal influence on lung cancer ... patients, prognosis. Previous research suggests that menopausal hormone ...
... SATURDAY, Jan. 22 (HealthDay News) -- Snow shoveling is a ... and 11,500 emergency department visits each year in the United ... of the problems occur among adults, kids under 19 experience ... The analysis of data from 1990 to 2006 found ...
Cached Medicine News:Health News:Brief Behavioral Counseling May Help Seniors Sleep 2Health News:Stress of War Spurs Changes in Brain Activity, Study Finds 2Health News:Breast Cancer Drug May Also Help Lung Cancer Patients 2Health News:Biodesign hosts international consortium on screening for lung cancer 2Health News:Anti-estrogen medication reduces risk of dying from lung cancer 2Health News:Snow Shoveling Injuries Affect Old and Young, Expert Warns 2
(Date:1/23/2015)... analysis of Centers for Medicare and Medicaid Services, (CMS) ... percent of seniors chose lower-cost preferred pharmacy plans that ... The findings were released by Drug Channels . ... of Medicare Part D," said Pharmaceutical Care Management Association ...
(Date:1/23/2015)... a third of reproductive-aged women enrolled in Medicaid, and more ... prescription for an opioid pain medication each year during 2008-2012, ... Weekly Report (MMWR). Opioids are typically prescribed ... They are also found in some prescription cough medications. The ...
(Date:1/23/2015)... baseball,s all-time hits leader, is the new spokesperson for the ... has announced. "Pete,s a Hall of Famer in ... board with Myoflex," said Ducere Pharma Chief Executive Officer ... known across all generations. The passion and intensity that Pete ...
Breaking Medicine Technology:New Analysis: 81 Percent of Medicare Part D Seniors Choose "Preferred Pharmacy" Plans in 2015 2Opioid painkillers widely prescribed among reproductive age women 2Opioid painkillers widely prescribed among reproductive age women 3Pete Rose bets on Myoflex to relieve aches and pains 2
... historic open letter to the World Health Organization ... Drugs (CoMeD) , and the United Methodist Women are seeking ... vaccines.  Currently, the mercury-based preservative Thimerosal, which is 49% mercury ... much of the world, despite the fact that it is ...
... Texas, March 15, 2012  OxySure® Systems, Inc. (OTCBB: ... emergency oxygen solutions with its "oxygen from powder" ... a Supplier Agreement ("Agreement") with W.W. Grainger, Inc. ... (Logo:  http://photos.prnewswire.com/prnh/20120315/DA71084LOGO ) In terms ...
Cached Medicine Technology:Global Call for Mercury-free Vaccines Issued 2OxySure Systems Announces Supplier Agreement With Grainger 2OxySure Systems Announces Supplier Agreement With Grainger 3
Inquire...
Inquire...
Spectrafuge 16M High speed microcentrifuge. High g-force for molecular biology applications. Brushless, maintenance-free motor. Easy to use control panel. Complete with 18 x 1.5/2.0 ml rotor. StripSp...
... the world's most popular Microhematocrit centrifuge and ... quiet, compact unit. It is your low ... For your microcentrifuge needs, order Cat. No. ... the MicroMB centrifuge, microcentrifuge rotor and a ...
Medicine Products: