Navigation Links
Gene Mutation Is Linked to Heart Muscle Disease
Date:7/15/2009

Findings shed light on understanding of dilated cardiomyopathy

WEDNESDAY, July 15 (HealthDay News) -- Gene mutations that cause heart muscle disease and chronic heart failure in some children and adults with dilated cardiomyopathy have been identified by researchers.

Dilated cardiomyopathy -- the most common cause of heart failure in young people and the most common reason for a heart transplant -- is a condition in which the heart becomes weakened and enlarged and is no longer able to pump blood efficiently.

The researchers screened 208 people and identified three variants of the ANKRD1 gene that were associated with dilated cardiomyopathy. According to their study, which appears online and in the July 21 print issue of the Journal of the American College of Cardiology, the ANKRD1 gene encodes a protein that plays a role in the structure and function of the heart.

"Our study indicates that variants in ANKRD1 result in dysfunction of the contraction apparatus and signaling machinery of the heart -- the method by which cells communicate to influence heart function," Dr. Jeffrey Towbin, co-director of the Heart Institute and director of cardiology at Cincinnati Children's Hospital Medical Center, said in a hospital news release. "This clarifies the mechanisms by which these inherited mutations cause disease in a subset of dilated cardiomyopathy patients."

He said the finding "provides us with a better understanding of the causes and mechanisms involved in the development of this disease and will enable better genetic testing and new treatments to be devised to improve outcomes of this serious disease."

More information

The American Heart Association has more about dilated cardiomyopathy.



-- Rober
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Gene Mutations May Cause Rare Neonatal Diabetes
2. Gene Mutation Linked to Parkinsons Disease
3. Research shows how genetic mutation causes epilepsy in infants
4. Gene Mutation Key to Infertility in Male Mice
5. Overlooked Mutation Can Spur HIV Drug Resistance
6. OHSU Cancer Institute researcher discovers what fuels certain cancer mutation
7. Breast cancer gene mutation more common in Hispanic, young black women, Stanford/NCCC study finds
8. BRCA1 Mutation Prevalent Among Hispanic, Younger Black Women
9. Ashkenazi ovarian cancer patients with BRCA mutations live longer than those with normal gene
10. BRCA Mutations Dont Raise Breast Cancer Risk Equally
11. Genetic Mutations Boost Prostate Cancer Risk
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Gene Mutation Is Linked to Heart Muscle Disease
(Date:4/25/2015)... Sports controversies continue to revolve around issues of abuse ... case with the Miami Dolphins and Richie Incognito, or off the ... Rice domestic abuse case. In a recent episode of SCI ... implications of locker room culture on teams. He examines what worked ... do to improve the locker room as a work place. ...
(Date:4/24/2015)... Will County, Illinois (PRWEB) April 24, 2015 ... 2015 event includes septic tank pumping ( http://www.zeitersseptics.com/multi-customer-discount.html ) ... of 3-customers to start the program. This does not ... may be applicable. Save $25-$65 per person. If someone ... Aerobic/Mechanical unit, or two tanks totaling approximately 2500 gallons ...
(Date:4/24/2015)... York (PRWEB) April 24, 2015 ... move forward in the federal multidistrict litigation underway ... According to court documents, the parties involved in ... April 16th detailing, among other things, preparation for ... that counsel for both plaintiffs and defendants have ...
(Date:4/24/2015)... Carinsurancequotesinfo.com has released a new blog post has ... qualify for auto insurance as a single parent. ... online, without having to follow a special process. The ... reduce their auto insurance expenses. The tips are presented ... , Clients can now visit an insurance brokerage website ...
(Date:4/24/2015)... St. Joseph, Missouri (PRWEB) April 24, 2015 ... solutions for veterinarians , UGA is now proud to ... oversee the care of 16,000 animals a year. This ... afford care for their animals. , After providing ... of Missouri Veterinary Medical Teaching Hospital (VMTH) wanted to ...
Breaking Medicine News(10 mins):Health News:David Steele Discusses Locker Room Culture on SCI TV 2Health News:David Steele Discusses Locker Room Culture on SCI TV 3Health News:Zeiter's Septics Inc. Offers Multi Customer Septic Tank Cleaning Program in Cook, Putnam & Will Counties in May 2015 2Health News:Zeiter's Septics Inc. Offers Multi Customer Septic Tank Cleaning Program in Cook, Putnam & Will Counties in May 2015 3Health News:Federal Lipitor Lawsuits Progress, as New Status Report Details Preparation for Upcoming Bellwether Trials 2Health News:Federal Lipitor Lawsuits Progress, as New Status Report Details Preparation for Upcoming Bellwether Trials 3Health News:Auto Insurance Discounts for Single Parents - How to Qualify for Low Rates 2Health News:University of Missouri Veterinary Medical Teaching Hospital Teams with UGA 2
... The National,Osteoporosis Foundation (NOF) has teamed up ... tour starting September 8th and culminating on,October 20th, ... to Start Right, Stay Strong for bone health. ... that offers individuals information on bone,health, exercise, and ...
... Health Accountability Foundation,s Report Card Provides Information on ... Quality, Mortality, Cost, LAKE SUCCESS, N.Y., Sept. 6 ... New Jersey have a unique new tool for evaluating,the ... State Health,Accountability Foundation,s first New York Regional Health Care ...
... Stryker Corporation,(NYSE: SYK ) announced that it ... at 4:30 p.m., Eastern Time, to discuss the Company,s,operating ... provide an,operational update. Operating results for the quarter ended ... day. Stephen P. MacMillan, President and Chief Executive ...
... in the stomach, this combo encourages carcinogens, study suggests ... is present in the stomach, vitamin C transforms from ... research suggests. , Researchers at Western Infirmary in Glasgow, ... (fat) in the upper stomach, which is particularly vulnerable ...
... Hospital have diagnosed two patients affected with vocal cord ... to irritating agents that are breathed in at the ... cases of patients with occupational vocal dysfunction. , Vocal ... in the vocal cords when inhaling. Under normal conditions, ...
... Two new issue briefs from,HealthFitness (OTC Bulletin Board: ... employer partners to create a culture of health. ... America Embraces New Culture of Health" features,HealthFitness CEO ... proactive vision for corporations to address the high ...
Cached Medicine News:Health News:National Osteoporosis Foundation Teams Up With Ladies Home Journal Magazine to Launch a 10-city Mall Walk Tour 2Health News:First New York/New Jersey Health Care Report Card Released 2Health News:First New York/New Jersey Health Care Report Card Released 3Health News:First New York/New Jersey Health Care Report Card Released 4Health News:First New York/New Jersey Health Care Report Card Released 5Health News:Stryker To Host Conference Call on October 17, 2007 2Health News:Vitamin C Plus Fat Might Spur Cancer 2Health News:Vocal cord dysfunction may be caused by work 2Health News:HealthFitness CEO Supports Move Toward Cultural Shift, and Science-Based Health Management Programming 2Health News:HealthFitness CEO Supports Move Toward Cultural Shift, and Science-Based Health Management Programming 3
(Date:4/24/2015)... 2015 In today,s ever-changing and increasingly ... the world to access diverse skill sets, set ... are many areas to misstep in the process ... practices are necessary and beneficial in order to ... to research by benchmarking firm, Best Practices, LLC, ...
(Date:4/24/2015)... April 24, 2015  Span-America Medical Systems, Inc. ... its fiscal 2015 second quarter results on Thursday, April ... The company will conduct a conference call ... to review the company,s financial and operating results for ... broadcast of the conference call will be available ...
(Date:4/24/2015)... 2015 Research and Markets ( http://www.researchandmarkets.com/research/pmbmv2/global_biobanking ... Biobanking Market 2015-2019" report to their offering. ... grow at a CAGR of 7.07% over the period ... divided into two segments: Equipment and Consumables. This report ... the Global Biobanking market for the period 2015-2019. ...
Breaking Medicine Technology:Work Around the Clock: Building Effective Global Capabilities 2Global Biobanking Market Report 2015-2019 - Increase in Strategic Collaborations with Beckman Coulter, Tecan & Thermo Fischer Scientific Dominating 2
... 2011 Cumberland Pharmaceuticals Inc. (Nasdaq: ... care and gastroenterology markets, today announced fourth quarter and full ... For the three months ended December 31, 2010, net revenue ... corresponding period in 2009. This quarterly revenue growth was largely ...
... Hill-Rom Holdings, Inc. (NYSE: HRC ) today ... immediately. "I am pleased to have someone of ... Mark Guinan, Senior Vice President and Chief Financial Officer of ... will contribute to the solid financial leadership of our company ...
Cached Medicine Technology:Cumberland Pharmaceuticals Reports Fourth Quarter and Full Year 2010 Financial Results 2Cumberland Pharmaceuticals Reports Fourth Quarter and Full Year 2010 Financial Results 3Cumberland Pharmaceuticals Reports Fourth Quarter and Full Year 2010 Financial Results 4Cumberland Pharmaceuticals Reports Fourth Quarter and Full Year 2010 Financial Results 5Cumberland Pharmaceuticals Reports Fourth Quarter and Full Year 2010 Financial Results 6Cumberland Pharmaceuticals Reports Fourth Quarter and Full Year 2010 Financial Results 7Cumberland Pharmaceuticals Reports Fourth Quarter and Full Year 2010 Financial Results 8Cumberland Pharmaceuticals Reports Fourth Quarter and Full Year 2010 Financial Results 9Cumberland Pharmaceuticals Reports Fourth Quarter and Full Year 2010 Financial Results 10Cumberland Pharmaceuticals Reports Fourth Quarter and Full Year 2010 Financial Results 11Cumberland Pharmaceuticals Reports Fourth Quarter and Full Year 2010 Financial Results 12Cumberland Pharmaceuticals Reports Fourth Quarter and Full Year 2010 Financial Results 13
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: