Navigation Links
Gene Mutation Improves Response to Lung Cancer Drug
Date:8/19/2009

Finding supports worthiness of genetic screening

WEDNESDAY, Aug. 19 (HealthDay News) -- People with lung cancer who are screened for a genetic mutation and then given a drug called Tarceva, which is believed to work well with that mutation, live longer than those without the mutation who take the drug, new research has found.

According to the Spanish authors of a study in the Aug. 20 issue of the New England Journal of Medicine, this type of widespread screening is actually doable and could lead to better decisions about treatment.

"They proved that it is worthy to test patients for the [epidermal growth factor receptor gene] mutations, and that if you have the mutations you are going to do well," said Dr. Edgardo Santos, an assistant professor of medicine in the hematology and oncology section at the University of Miami's Sylvester Comprehensive Cancer Center. "If we are moving toward personalized medicine in the future, I think this is the way to go -- that patients be tested and use the drug if indicated."

People who have advanced non-small-cell lung cancer who also have certain mutations in the epidermal growth factor receptor gene (EGFR) tend to respond better to Tarceva and Iressa. Both of these drugs are tyrosine kinase inhibitors, which interfere with cancer cells' ability to multiply. Non-small-cell lung cancer is the most common form of lung cancer.

The researchers screened lung cancer samples from 2,105 people at 129 institutions in Spain for two different EGFR mutations.

Those with mutations (16.6 percent of the sample, considered a sizable proportion) were put on Tarceva. They survived a median of 14 months without progression of their disease and 27 months overall, more than twice as long as the rates seen in other treatment groups, Santos said. This was true regardless of whether Tarceva was given as first-line, second-line or third-line therapy.

"Basically, t
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Mutation in renin gene linked to inherited kidney disease
2. Genome of Leukemia Patient Reveals Common Mutations
3. Boehringer Ingelheim to Commence Phase III Study Investigating the Role of BIBW 2992 as First-Line Treatment for Non-Small Cell Lung Cancer (NSCLC) Patients with EGFR Mutations
4. Gene Mutation Could Be Key to Rare Blood Vessel Disease
5. Study Shows a Link Between Schizophrenia & Genetic Mutations
6. Gene Mutation Is Linked to Heart Muscle Disease
7. JNCI news brief: Hepatitis B virus mutations may predict risk of liver cancer
8. Cancer Researchers Link DICER1 Gene Mutation to Rare Childhood Cancer
9. New Cancer Drug Fights Tumors in Those With BRCA Mutations
10. Clarient Launches New Gene Mutation Test to Help Select Therapy for Non-Small Cell Lung Cancer
11. USC researchers identify DNA mutation that occurs at beginning point of T-cell lymphoma
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Gene Mutation Improves Response to Lung Cancer Drug
(Date:10/30/2014)... Home Care Assistance – Halton/Peel Region ( ... senior care, is weighing in on a recent study ... study, performed by the University of Illinois, analyzed 88 ... a week-long period and observed how much time was ... examining the structural soundness of the white matter in ...
(Date:10/30/2014)... FL (PRWEB) October 30, 2014 ... Joint Commission Accredited teleradiology and specialty telemedicine solutions ... in addition to its existing teleradiology services at ... second opinion and expert telemedicine services, to the ... , As a result of this innovative partnership, ...
(Date:10/30/2014)... 2014 Victory Healthcare, a privately ... third quarter infection rates and patient satisfaction scores. ... of only two percent or less, and the ... 98 percent. , “We are delighted with our ... satisfaction scores,” said Robert Helms, chairman and CEO ...
(Date:10/30/2014)... HealthDay Reporter WEDNESDAY, Oct. ... chemical during pregnancy may have effects on genital development in ... baby boys born to moms with greater exposure to a ... -- the space between the genitals and anus. Anogenital distance ... of exposure to androgens ("male" hormones) during pregnancy. The ...
(Date:10/30/2014)... WEDNESDAY, Oct. 29, 2014 (HealthDay News) -- Americans, opinions ... political lines, a new study finds. Democratic voters ... (ACA), according to the researchers. Almost three-quarters of Democrats ... ACA. Thirty percent want Congress to implement the current ... of the ACA. Among Independent voters, one-third want ...
Breaking Medicine News(10 mins):Health News:Home Care Assistance – Halton/Peel Region, a Top Provider of In-Home Care, Responds to Study Linking Exercise to Healthier Senior Brains 2Health News:Home Care Assistance – Halton/Peel Region, a Top Provider of In-Home Care, Responds to Study Linking Exercise to Healthier Senior Brains 3Health News:USARAD HOLDINGS INC, SECONDOPINIONS.COM® Pioneers Specialty On-Demand Telemedicine And Second Opinion Service At Houston-Based, Mission Bend Freestanding ER Chain 2Health News:USARAD HOLDINGS INC, SECONDOPINIONS.COM® Pioneers Specialty On-Demand Telemedicine And Second Opinion Service At Houston-Based, Mission Bend Freestanding ER Chain 3Health News:Victory Healthcare Releases Q3 Satisfaction, Infection Rates 2Health News:Victory Healthcare Releases Q3 Satisfaction, Infection Rates 3Health News:Plastics' Chemical May Affect Baby Boys' Genital Development 2Health News:Plastics' Chemical May Affect Baby Boys' Genital Development 3Health News:Voters' Views on Obamacare Split Along Party Lines 2
... in the retina that is responsible for maintaining the health ... in a living retina for the first time. , The ... identify the onset of many diseases of the eye long ... issue of Investigative Ophthalmology and Visual Science ., "Our ...
... Tired of Putting Money in the Hands of Beauty Corporations ... / or Counseling to Remain Youthful? Now one does ... Never Before Published Secrets to Eternal Youth and Immortality, gives ... so that folks can attain and maintain the Age they ...
... Jade Goody who will be left behind without a ... Chantel "Chani" Christie who recently won the 2009 Martin ... is set to donate proceeds from her debut album ... star, Jade Goody. In addition, she also plans to ...
... facility already ahead of scheduleMARLTON, N.J., Feb. 25 ... exempt bonds from the New Jersey Health Care Facilities ... The bonds will be used to continue the financing ... our plan for finance in place and have met ...
... continued positive cash flow from operationsBOSTON, Feb. 25 ... a leader in radiology and medical image and ... for the fourth quarter and year ended December ... Financial Highlights Revenue : Total revenue for ...
... Feb. 25 Mesa Laboratories, Inc. (Nasdaq: ... manufacturing quality control applications, today announced the appointment of ... extensive experience to Mesa from his role as Chief ... Inc., a registered investment adviser based in New York ...
Cached Medicine News:Health News:'Dark cells' of living retina imaged for the first time 2Health News:'Dark cells' of living retina imaged for the first time 3Health News:What the Billion Dollar Beauty Industry Does Not Want Leaked: That One Can Actually Reverse Aging for Free by Moving Only to the Right. We Smell a Nobel. 2Health News:Chantel 'Chani' Christie Will Donate Proceeds From Her Top-Selling Debut Album 'My Dream' to the Children of Terminally Ill TV Star Jade Goody 2Health News:Virtua Health Takes Next Step for Continuing Hospital Construction 2Health News:AMICAS Reports Financial Results for the Fourth Fiscal Quarter and Year Ended December 31, 2008 2Health News:AMICAS Reports Financial Results for the Fourth Fiscal Quarter and Year Ended December 31, 2008 3Health News:AMICAS Reports Financial Results for the Fourth Fiscal Quarter and Year Ended December 31, 2008 4Health News:AMICAS Reports Financial Results for the Fourth Fiscal Quarter and Year Ended December 31, 2008 5Health News:AMICAS Reports Financial Results for the Fourth Fiscal Quarter and Year Ended December 31, 2008 6Health News:AMICAS Reports Financial Results for the Fourth Fiscal Quarter and Year Ended December 31, 2008 7Health News:AMICAS Reports Financial Results for the Fourth Fiscal Quarter and Year Ended December 31, 2008 8Health News:AMICAS Reports Financial Results for the Fourth Fiscal Quarter and Year Ended December 31, 2008 9Health News:AMICAS Reports Financial Results for the Fourth Fiscal Quarter and Year Ended December 31, 2008 10Health News:AMICAS Reports Financial Results for the Fourth Fiscal Quarter and Year Ended December 31, 2008 11Health News:AMICAS Reports Financial Results for the Fourth Fiscal Quarter and Year Ended December 31, 2008 12Health News:AMICAS Reports Financial Results for the Fourth Fiscal Quarter and Year Ended December 31, 2008 13Health News:AMICAS Reports Financial Results for the Fourth Fiscal Quarter and Year Ended December 31, 2008 14Health News:Mesa Labs Announces Appointment of New Director 2
(Date:10/30/2014)... The global market for human vaccines ... of new vaccines. These new products and other ... The Kalorama information report examines the global market ... vaccines for diseases that are already vaccine-preventable. ... communities from diseases spread by person-to-person transmission. The ...
(Date:10/27/2014)... Calif. , Oct. 27, 2014  RenovoRx, a ... blood flow and delivery of fluids to selected sites ... Board of Directors has appointed Shaun Bagai ... of the RenovoRx Board of Directors. Bagai brings more ... industry. Bagai joined RenovoRx in June 2014 ...
(Date:10/27/2014)... 27, 2014  In the last few weeks, Ebola has gone ... to a worldwide crisis when a traveler to ... died, and two nurses were infected. While much of ... use of modern technology, such as electronic health records (EHRs), to ... This week, InformationWeek Healthcare Editor Alison Diana fills in ...
Breaking Medicine Technology:Vaccines 2014: World Market Analysis, Key Players, Trends, Pediatric and Adult Segments 2Vaccines 2014: World Market Analysis, Key Players, Trends, Pediatric and Adult Segments 3RenovoRx Board Names Shaun R. Bagai as CEO 2EHRs in the Age of Ebola: Discuss on InformationWeek 2EHRs in the Age of Ebola: Discuss on InformationWeek 3
... 2012 /PRNewswire-Asia/ -- China Kanghui Holdings (NYSE: ... leading domestic developer, manufacturer and marketer of orthopedic ... operating subsidiaries, Beijing Libeier Biology Engineering Research Institute ... Ltd, have received approvals from relevant PRC authorities ...
... MAPLE GROVE, Minn., Jan. 11, 2012  Snow tires? Check! ... Just like a car, you need to prepare your ... extreme temperature changes can result in skin that is ... brakes on severe dry skin before it starts with ...
Cached Medicine Technology:China Kanghui Holdings Renews High and New Technology Enterprises Status of Its PRC Operating Subsidiaries 2Don't Let Your Skin Take a Backseat As You Prepare for Winter 2Don't Let Your Skin Take a Backseat As You Prepare for Winter 3
Endoscopes are also available in fully autoclavable models in 1.8, 2.7, 4.0. 5.0 and 10.0 mm diameters. Manufactured with precise swiss lenses. Built-in temperature measuring device to exactly determ...
Cottle Tenaculum Skin Hook. 5 1/2" small, shallow curve....
Goldman single hook....
Needle tip electrode, davol advantage electrosurgical attachments, 33cm (with extendible outer sheath), non-sterile. These products are supplied non-sterile and must be sterilized before use. Reusabl...
Medicine Products: