Navigation Links
Gene Mutation Can Leave People Without Fingerprints
Date:8/4/2011

THURSDAY, Aug. 4 (HealthDay News) -- People with a rare condition where they are born without fingerprints may have a genetic mutation, according to a new study.

The findings, published in the Aug. 4 online edition of the American Journal of Human Genetics, could shed light on how fingerprints are formed as well as how genetic mutations can help uncover unknown aspects of human biology, the researchers pointed out.

"We know that fingerprints are fully formed by 24 weeks after fertilization and do not undergo any modification throughout life," the study's senior author, Dr. Eli Sprecher from Tel Aviv Sourasky Medical Center in Israel, said in a journal news release. "However, the factors underlying the formation and pattern of fingerprints during embryonic development are largely unknown."

In investigating adermatoglyphia, which causes people to be born without fingerprints (dermatoglyphs, or ridges on the fingertips), and also affects the palms, toes and soles, researchers examined a large Swiss family affected by the extremely rare condition. Not only were they all born without fingerprints, they also lacked the usual number of sweat glands.

Through genetic analysis of the family members with and without the condition, scientists revealed the disease is caused by a mutation in a gene found in the skin called the SMARCAD1 gene. They also found a short version of this gene was mutated in individuals with the disease.

"Taken together, our findings implicate a skin-specific version of [the gene] SMARCAD1 in the regulation of fingerprint development," Sprecher said. "Although little is known about the function of full-length SMARCAD1 and virtually nothing regarding the physiological role of the skin-specific version of the gene, it is tempting to speculate that SMARCAD1 in the skin may target genes involved in dermatoglyph and sweat gland development, two structures jointly affected in the present family."

The researchers noted that the findings may contribute to the investigation of other diseases affecting more than the skin.

More information

The U.S. Federal Bureau of Investigation provides more information on fingerprint identification.

-- Mary Elizabeth Dallas

SOURCE: Cell Press, news release, Aug. 4, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Single gene mutation induces endometrial cancer
2. Genetic Mutation Linked to Prostate Cancer in Blacks
3. Gene Mutations Identified for Charcot-Marie-Tooth Syndrome
4. Study shows that mutations in 1 gene cause many cancers
5. Parkinsons Linked to Genetic Mutation
6. Breast cancer patients with BRCA mutations 4 times more likely to get cancer in opposite breast
7. Gene Mutations Up Risk for Cancer in Opposite Breast
8. Gene Mutation Ups Risk of Sudden Death in People with Epilepsy
9. Heart Disease Among Childhood Cancer Survivors Tied to Gene Mutations
10. New research indicates that DNA sequence itself influences mutation rate
11. Single Lung Tumor Contains 50,000 Mutations
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Gene Mutation Can Leave People Without Fingerprints
(Date:6/26/2016)... ... June 26, 2016 , ... Many ... been diagnosed with endometriosis. These women need a treatment plan to not only ... approach that can help for preservation of fertility and ultimately achieving a pregnancy. ...
(Date:6/25/2016)... ... ... First Choice Emergency Room , the largest network of independent freestanding emergency ... its new Mesquite-Samuell Farm facility. , “We are pleased to announce Dr. Ogunleye ... M. Muzzarelli, Executive Medical Director of First Choice Emergency Room. , Dr. Ogunleye ...
(Date:6/24/2016)... CA (PRWEB) , ... June 24, 2016 , ... A ... procedures that most people are unfamiliar with. The article goes on to state that ... but also many of these less common operations such as calf and cheek reduction. ...
(Date:6/24/2016)... ... June 24, 2016 , ... Global law firm Greenberg Traurig, ... Elite. The attorneys chosen by their peers for this recognition are considered among the ... Traurig Shareholders received special honors as members of this year’s Legal Elite Hall of ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... Clinical Decision Making in Emergency Medicine conference in Ponte Vedra Beach, FL. The ... published in Emergency Medicine Practice and Pediatric Emergency Medicine Practice. , ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... Jazz Pharmaceuticals plc (Nasdaq: JAZZ ... Antitrust Improvements Act of 1976, as amended ("HSR"), with ... ("Celator"; Nasdaq: CPXX ) expired effective June ... As previously announced on May 31, 2016, Jazz ... under which Jazz Pharmaceuticals has commenced a tender offer ...
(Date:6/26/2016)... VEGAS , June 26, 2016 ... to value-based care operating models within the health care ... enable greater financial efficiency , Deloitte offers a ... the key business issues impacting efficient cost optimization: labor ... , These services facilitate better outcomes and better ...
(Date:6/24/2016)... OAKLAND, N.J. , June 24, 2016 /PRNewswire/ ... in the design, development and manufacturing of collagen ... and regeneration announced today that Bill Messer ... Sales and Marketing to further leverage the growing ... surgery medical devices. Bill joins the ...
Breaking Medicine Technology: