Navigation Links
Gene May Boost Death Risk From Most Common Thyroid Cancer

FRIDAY, April 12 (HealthDay News) -- Researchers have pinpointed a genetic mutation that is strongly associated with an increased risk of death in people with thyroid cancer.

The investigators followed more than 1,800 patients after their initial treatment for papillary thyroid cancer, which accounts for 85 percent to 90 percent of all thyroid cancers.

After an average follow-up period of 33 months, 5 percent of those with the BRAF V600E mutation had died, compared with 1 percent of those without the mutation, according to the study in the April 10 issue of the Journal of the American Medical Association.

However, the link between this mutation and increased risk of death was not independent of tumor characteristics, the study authors noted in a journal news release.

This, and the fact that the overall death rate from papillary thyroid cancer is low, means that it is unclear how to use these findings to reduce death risk in patients with this type of cancer, said Dr. Mingzhao Xing, of the Johns Hopkins University School of Medicine, and colleagues.

The overall five-year survival rate for patients with papillary thyroid cancer is 95 percent to 97 percent. It's a challenge to distinguish patients who require aggressive treatment in order to reduce their risk of death from patients who do not, the researchers explained.

Even so, the authors of an accompanying editorial pointed out that the study provided important insight.

According to the editorialists, Dr. Anne Cappola and Dr. Susan Mandel of the University of Pennsylvania, "Although these findings do not support widespread BRAF V600E testing, they do support the need for additional study of how BRAF testing can be used to improve the already excellent prognosis of patients with papillary thyroid cancer."

While the study found an association between the gene mutation and thyroid cancer survival, it did not establish a cause-and-effect relationship.

More information

The American Cancer Society has more about thyroid cancer.

-- Robert Preidt

SOURCE: Journal of the American Medical Association, news release, April 9, 2013

Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Vitamin D proven to boost energy -- from within the cells
2. New Electronic Earplugs Protect Ears and Boost Hearing
3. R.B.I. Vision Performance Supplement Boosts Athletic Ability Naturally
4. Bigorexics Want to Boost Their Masculinity
5. Facebook a Boost for Your Self-Worth?
6. Shorter Shifts for Medical Interns May Not Boost Patient Safety
7. News Coverage of Shootings May Boost Stigma of Mental Illness
8. #1 Natural Testosterone Booster Offers No Charge International Shipping of Their Highly Popular Mens All Natural Testosterone Supplement
9. Omega XL Reports New Independent Study: Omega-3s Can Boost Children’s IQ
10. Scientists ID Antibody That Might Boost Cancer Therapy
11. Oxblue Construction Cameras Help Two Universities Embarked on Major Building Projects Boost Stakeholder Confidence and Improve Project Management
Post Your Comments:
Related Image:
Gene May Boost Death Risk From Most Common Thyroid Cancer
(Date:11/25/2015)... ... ... Today, Mothers Against Drunk Driving (MADD) learned that the number of ... time since 2011. In 2014, there were 9,967 fatalities involving an alcohol impaired driver, ... Traffic Safety Administration (NHTSA), 32,675 people were killed in traffic crashes in 2014. Drunk ...
(Date:11/25/2015)... ... November 25, 2015 , ... In honor ... Periwinkle Pioneers, individuals and groups responsible for advancing care for pulmonary hypertension (PH) ... nominated by the public, will receive special recognition throughout 2016 as part of ...
(Date:11/25/2015)... ... 25, 2015 , ... Privately owned Contract Development and Manufacturing ... its current state of the art research, development and manufacturing facility outside of ... manufacturing capacity as well as to support its clients’ growing research and development ...
(Date:11/25/2015)... ... November 25, 2015 , ... Many people know of ... weight gain, cold hands, and dry skin. But many people who find their cholesterol ... exercise regimen instead of their thyroid, especially if they don’t have any of the ...
(Date:11/25/2015)... ... November 25, 2015 , ... Since its launch in ... involving adult stem cell therapies to patients with chronic degenerative medical conditions. Now, ... a Registered Trademark (RTM). , Organizations are required to hold a registered trademark ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)... 2015  Today AVACEN Medical announced the issue of United States patent ... Adjustment ". This patent shields the company,s AVACEN 100 dry heat therapy medical device and specific ... Photo - ... ... ...
(Date:11/25/2015)... YORK , November 25, 2015 ... market of self-monitoring blood glucose devices was valued at ... grow with a CAGR of 5.7% during 2015 - ... geriatric population and increasing prevalence of diabetes. In addition, ... diabetes care is also contributing to the growth of ...
(Date:11/25/2015)... Pennsylvania , November 25, 2015 - ... Continuing Medical Education (CME) --> ... Continuing Medical Education (CME) --> ... Care Continuing Medical Education (CME) ... medical information products and services, will feature latest diagnostic imaging textbooks ...
Breaking Medicine Technology: