Navigation Links
Gene Linked to Start of Puberty
Date:2/15/2012

By Randy Dotinga
HealthDay Reporter

WEDNESDAY, Feb. 15 (HealthDay News) -- Researchers report that they've discovered the importance of a particular gene in kicking off puberty in humans, a finding that offers insight into how the mysterious process begins and could help children who suffer from a rare disease that prevents the start of puberty.

An analysis of the DNA of a family whose members have suffered from the disease confirmed that the gene is vital because it paves the way for the body to process a hormone known as kisspeptin.

"Without kisspeptin, a human being cannot attain sexual characteristics of his/her gender and child-bearing capacity. Kisspeptin is absolutely required for the start of the puberty process in humans," said study author Dr. A. Kemal Topaloglu, of the department of pediatric endocrinology at Cukurova University in Adana, Turkey.

A mutation in the gene, the researchers found, can cause a rare condition called hypogonadotropic hypogonadism, in which children don't fully enter puberty.

Dr. William F. Crowley Jr., director of the Harvard Reproductive Endocrine Sciences Center at Harvard Medical School, said the condition affects no more than one in 10,000 children, and perhaps even fewer.

"They look like they're 12 years old, even when they're 20. They don't have a growth spurt and tend to be short, and the males don't shave," Crowley said.

In the new study, researchers examined the genetic makeup of a family in which four daughters had the disease. They linked the disease to a mutation in the gene that creates a receptor that processes the kisspeptin hormone.

The hormone can be used to make the brain produce hormones that stimulate the maturation of ovaries and testicles, Topaloglu said. Also, medications that shut down the hormone could be used to treat a condition that causes early puberty, he said, or serve as a contraceptive.

"Such drugs can also be
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Molecular pathways linked to sex, age affect outcomes in lung cancer
2. Physical Changes in Brain Linked to Altered Spirituality
3. Migraine Linked to Increased Heart Attack Risk
4. First Gene Variants Linked to Stuttering Discovered
5. Flat Head Syndrome Linked to Developmental Delays
6. Untreated poor vision in elderly linked to dementia, University of Michigan study shows
7. Genetic Mutation Linked to Prostate Cancer in Blacks
8. Sleep More, Lose Weight – Sleeplessness Linked to Obesity
9. Antibodies linked to cardiovascular disease increase in patients with active lupus
10. High Hormone Level Linked to Cancer Death in Older Men
11. Hormone replacement therapy linked to increased lung cancer risk
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Gene Linked to Start of Puberty 
(Date:7/3/2015)... (PRWEB) , ... July 03, 2015 , ... Jennifer Renee ... First Choice Emergency Room , the largest network of independent freestanding emergency rooms in ... facility medical director of our Sienna Plantation facility,” said Executive Medical Director of First ...
(Date:7/3/2015)... ... July 03, 2015 , ... Every year, One-to-1 Fitness ... where they provide members of the Red Deer community with free fitness training and ... fitness training, games, food, events and entertainment raised thousands of charity dollars and ended ...
(Date:7/2/2015)... ... July 02, 2015 , ... sweetFrog Enterprises, LLC. is pleased to announce the ... sweetFrog store located in the Lone Star State. The premium frozen yogurt chain was ... , The store, which opened July 1 at Duke’s Travel Plaza, is located at:, ...
(Date:7/2/2015)... ... July 02, 2015 , ... Many Fourth of July celebrations will include ... Amica Insurance is sharing some tips to promote the proper use of fireworks. ... to the emergency room daily with fireworks-related injuries in the month surrounding the Fourth ...
(Date:7/2/2015)... ... ... As Americans celebrate the Fourth of July outdoors this weekend, local physicians are warning ... UV Safety Month, and physicians at American Family Care and AFC Doctors Express urgent ... most skin cancers can be found early with regular skin exams. Physicians can give ...
Breaking Medicine News(10 mins):Health News:Dr. Jennifer Renee Hanes Named by First Choice Emergency Room as Medical Director of Missouri City, TX Facility 2Health News:Dr. Jennifer Renee Hanes Named by First Choice Emergency Room as Medical Director of Missouri City, TX Facility 3Health News:Red Deer Fitness Studio Raises $10,000 for Charity Organization with 24-Hour Train-a-Thon 2Health News:Red Deer Fitness Studio Raises $10,000 for Charity Organization with 24-Hour Train-a-Thon 3Health News:sweetFrog Expands Texas Footprint with Location in Canton 2Health News:6 Fireworks Safety Tips from Amica Insurance 2Health News:Local Physicians Warn of Holiday Health Hazards 2Health News:Local Physicians Warn of Holiday Health Hazards 3Health News:Local Physicians Warn of Holiday Health Hazards 4
... that adolescents were at the greatest risk of smoking when ... parents, smoking quickly reached high levels and persisted over time. ... Health Psychology , draws from the long-running Indiana University ... behavior is influenced by both genetics and the environment. , ...
... The use of ultrasound waves for deep vein thrombosis (DVT) ... clot-busting drugs alone, according to researchers at Emory University. The ... annual VEITHsymposium in New York City. , "These clots are ... the more quickly you can eliminate them the better," says ...
... its kind, researchers at the Yerkes National Primate ... have developed a multidisciplinary approach involving immunology, genomics ... vaccine without exposing individuals to infection. This approach ... vaccines--that of only being able to determine immunity ...
... rehab facility located in Palm Springs, California has recently completed work ... the décor of the facility, but the overall recovery experience as ... ... 2008 -- The remodeling project, which took nearly a year and ...
... women need more culturally targeted information, study finds , , ... almost six times more likely than white women to ... breast cancer treatment, a new report says. , Researchers ... that despite being just as involved with their doctor ...
... now happening for Medicare Advantage Plans. These plans cover expenses not ... Many consumers are now shopping online for instant quotes and applications. ... ... is pleased to announce open enrollment for Medicare Supplement plans . ...
Cached Medicine News:Health News:Smoking, teens and their parents: New research 2Health News:Ultrasound waves aid in rapid treatment of DVT 2Health News:Researchers discover strategy for predicting the immunity of vaccines 2Health News:California Drug Rehab Facility Completes Comprehensive Remodeling Project 2Health News:California Drug Rehab Facility Completes Comprehensive Remodeling Project 3Health News:MediGap Advisors Announces Open Enrollment for Medicare Supplement Plans 2
(Date:7/2/2015)... , July 3, 2015 ... adquisición del 100% de participación en ZAO "Biocom" ... adquisición marca la incursión de Lupin en el ... de RUB en ventas, colocándolo como uno de ... 2014 (IMS Health). Durante más de una década, ...
(Date:7/2/2015)... DIEGO , July 2, 2015 ResMed Inc. ... its fourth quarter and fiscal year ended June 30, 2015 ... Stock Exchange market close. A press release with ResMed,s results ... the company will host a webcast to discuss operating results ... to begin at 1:30 p.m. US Pacific Time and the ...
(Date:7/2/2015)... -- Releases of the genetically engineered Oxitec ... , , reduced the dengue mosquito population in an ... 95%, well below the modelled threshold for epidemic disease ... The journal PLOS Neglected Tropical Diseases published today the ... The results showed that in Juazeiro city, northeast ...
Breaking Medicine Technology:Lupin adquiere Biocom en Rusia 2Lupin adquiere Biocom en Rusia 3ResMed to Announce Fourth Quarter and Fiscal Year-End 2015 Results 2Oxitec Mosquito Works to Control Aedes aegypti in Dengue Hotspot 2Oxitec Mosquito Works to Control Aedes aegypti in Dengue Hotspot 3
... Nov. 17 Diplomat Specialty Pharmacy announced today the opening ... has 6 additional locations in Michigan, Ohio, Illinois and Florida. ... in California will potentially impact over 1 million people," stated ... Bernardino location is an important resource for those patients. It ...
... , CAMBRIDGE, Mass., Nov. 17 Mersana ... additional preliminary results from an ongoing Phase 1 study of ... tumors. The results were presented in a poster session ... Cancer Therapeutics in Boston, MA November 15-19, 2009. ...
Cached Medicine Technology:Diplomat Specialty Pharmacy Continues to Expand - Opens Location in Southern California 2Mersana Therapeutics Provides Clinical Update from Ongoing Phase 1 Study of XMT-1001 in Patients with Advanced Solid Tumors 2Mersana Therapeutics Provides Clinical Update from Ongoing Phase 1 Study of XMT-1001 in Patients with Advanced Solid Tumors 3
... is a revolutionary Electronic Medical Office (EMO) ... customized for the unique needs of your ... of an electronic record system (EMR, EHR, ... practice to a new level of efficiency ...
... AcerMed's Cardiology specific EMR / ... of Cardiologists nationwide,enabling more effective patient ... other staff clinicians with critical information ... better patient care.,Our Cardiology specific clinical ...
... A1cNow InView System is ... healthcare professionals and,consumers with ... A1C status, the "gold ... management ,without the time, ...
Inquire...
Medicine Products: