Navigation Links
Gene Linked to Separation Anxiety
Date:11/16/2011

WEDNESDAY, Nov. 16 (HealthDay News) -- Scientists who identified a gene linked to separation anxiety say their finding could lead to more targeted treatments for anxiety disorders.

The researchers assessed separation anxiety in children with two rare genetic disorders called 7q11.23 duplication syndrome (Dup7q11.23) and Williams-Beuren syndrome (WBS).

Dup7q11.23 is a developmental disorder characterized by social anxiety and specific phobias. It's caused by extra copies of 26 genes on chromosome seven, including the GTF2I gene. Children with Williams-Beuren syndrome, which is caused by a deletion of 7q11.23, have cognitive deficits but are highly social and don't have social anxieties. GTF2I is typically one of the genes deleted in children with Williams-Beuren syndrome.

The researchers found that 26 percent of the children with Dup7q11.23 had separation anxiety, compared with less than 5 percent of children with Williams-Beuren syndrome and those in the general population.

To further investigate the link between GTF2I and separation anxiety, the researchers bred mice with either additional or missing copies of the gene. When separated from their mothers, mouse pups with extra copies of the gene vocalized more than normal, while pups with fewer copies of the gene did not.

The study was presented Tuesday at the annual meeting of the Society for Neuroscience in San Diego.

"Our research provides evidence of the first gene to cause separation anxiety," senior author Lucy Osborne, of the University of Toronto, said in a society news release. "These findings may lead to the development of more targeted therapies for anxiety disorders."

Because this study was presented at a medical meeting, the data and conclusions should be viewed as preliminary until published in a peer-reviewed journal.

More information

The Nemours Foundation has more about separation anxiety.

-- Robert Preidt

SOURCE: Society for Neuroscience, news release, Nov. 15, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. New test for coronary artery disease linked to higher rates of cardiac procedures and greater costs
2. Vascular risk linked to long-term antiepileptic drug therapy
3. Stomach flu may be linked to food allergies
4. Exposure to Toxic Solvents Linked to Parkinsons Disease
5. NIH-funded twin study finds occupational chemical exposure may be linked to Parkinsons risk
6. Poor sleep habits linked to increased risk of fibromyalgia in women
7. Sepsis Plus Heart Rhythm Disorder Linked to Stroke, Death
8. Woodsmoke from cooking fires linked to pneumonia
9. Vaccine Cut Flu Strain Linked to Meningitis, Pneumonia
10. Study helps eliminate causes for joint pain linked to commonly used breast cancer drugs
11. Classic Restless Legs Syndrome Not Linked to Parkinsons
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/21/2017)... ... July 21, 2017 , ... In ... researchers from the Multicenter Orthopaedics Outcome Network (MOON) demonstrated that patients could perform ... surgery, though activity levels decline over time. The study, presented today at the ...
(Date:7/21/2017)... ... July 21, 2017 , ... ... concussion rates are on the rise, say researchers presenting their work at the ... Ontario, Canada. , “The combination of evaluating the patterns of change in concussion ...
(Date:7/20/2017)... ... July 20, 2017 , ... ChenMed , a leading provider ... JenCare Senior Medical Center as Richmond Chief Medical Officer. Dr. McCarter, formerly ... Associate Chief Medical Officer of Ambulatory Services for the UVA Health System, brings 30 ...
(Date:7/20/2017)... (PRWEB) , ... July 20, ... ... provider of enterprise-grade IT operations analytics and application performance monitoring (APM) solutions, ... world’s largest healthcare services providers. , According to Peter Ohrenberger, sales director ...
(Date:7/20/2017)... ... July 20, 2017 , ... For individuals with extended ... The adjustable beds used in such facilities are specially designed to accommodate patients with ... support. , An inventor from Rochester, Ind., has invented the patent-pending PORTABLE ARM ...
Breaking Medicine News(10 mins):
(Date:7/21/2017)... , July 21, 2017 Did you know that PhRMA ... 2016? Or that combined spending on brand medicines, generics and the ... with brands accounting for just half of this (7 percent)? Or ... thirds of the world,s venture capital investments in high-growth biopharmaceutical startups? ... ...
(Date:7/19/2017)... RALEIGH, N.C. , July 19, 2017  Mako ... Veteran Affairs, and the Military Family Assistance Fund (MFA) ... Louisiana to visit with their families one ... the funding to coordinate the travel and logistics needed ... supporting our deployed soldiers and their families. We just ...
(Date:7/15/2017)... , July 15, 2017 Enterin Inc., a ... treat Parkinson,s disease (PD), today announced the completion of a ... investors New Ventures III, as well as the participation of ... absolutely thrilled to have the support of New Ventures III ... investors as validation of the potential of our platform technology ...
Breaking Medicine Technology: