Navigation Links
Gene Linked to Separation Anxiety
Date:11/16/2011

WEDNESDAY, Nov. 16 (HealthDay News) -- Scientists who identified a gene linked to separation anxiety say their finding could lead to more targeted treatments for anxiety disorders.

The researchers assessed separation anxiety in children with two rare genetic disorders called 7q11.23 duplication syndrome (Dup7q11.23) and Williams-Beuren syndrome (WBS).

Dup7q11.23 is a developmental disorder characterized by social anxiety and specific phobias. It's caused by extra copies of 26 genes on chromosome seven, including the GTF2I gene. Children with Williams-Beuren syndrome, which is caused by a deletion of 7q11.23, have cognitive deficits but are highly social and don't have social anxieties. GTF2I is typically one of the genes deleted in children with Williams-Beuren syndrome.

The researchers found that 26 percent of the children with Dup7q11.23 had separation anxiety, compared with less than 5 percent of children with Williams-Beuren syndrome and those in the general population.

To further investigate the link between GTF2I and separation anxiety, the researchers bred mice with either additional or missing copies of the gene. When separated from their mothers, mouse pups with extra copies of the gene vocalized more than normal, while pups with fewer copies of the gene did not.

The study was presented Tuesday at the annual meeting of the Society for Neuroscience in San Diego.

"Our research provides evidence of the first gene to cause separation anxiety," senior author Lucy Osborne, of the University of Toronto, said in a society news release. "These findings may lead to the development of more targeted therapies for anxiety disorders."

Because this study was presented at a medical meeting, the data and conclusions should be viewed as preliminary until published in a peer-reviewed journal.

More information

The Nemours Foundation has more about separation anxiety.

-- Robert Preidt

SOURCE: Society for Neuroscience, news release, Nov. 15, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. New test for coronary artery disease linked to higher rates of cardiac procedures and greater costs
2. Vascular risk linked to long-term antiepileptic drug therapy
3. Stomach flu may be linked to food allergies
4. Exposure to Toxic Solvents Linked to Parkinsons Disease
5. NIH-funded twin study finds occupational chemical exposure may be linked to Parkinsons risk
6. Poor sleep habits linked to increased risk of fibromyalgia in women
7. Sepsis Plus Heart Rhythm Disorder Linked to Stroke, Death
8. Woodsmoke from cooking fires linked to pneumonia
9. Vaccine Cut Flu Strain Linked to Meningitis, Pneumonia
10. Study helps eliminate causes for joint pain linked to commonly used breast cancer drugs
11. Classic Restless Legs Syndrome Not Linked to Parkinsons
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... N.J. (PRWEB) , ... June 27, 2016 , ... Quality ... sources, yet in many ways they remain in the eye of the beholder, according ... (EBO), a publication of The American Journal of Managed Care. For the full issue, ...
(Date:6/26/2016)... ... ... Brent Kasmer, a legally blind and certified personal trainer is helping to develop a weight ... app plans to fix the two major problems leading the fitness industry today:, ... program , They don’t eliminate all the reasons people quit their exercise program ...
(Date:6/25/2016)... ... June 25, 2016 , ... The temporary closing of Bruton Memorial Library on June 21 ... brings up a new, often overlooked aspect of head lice: the parasite’s ability to live ... not a common occurrence, but a necessary one in the event that lice have simply ...
(Date:6/25/2016)... , ... June 25, 2016 , ... ... and non-athletes recover from injury. Recently, he has implemented orthobiologic procedures as a ... area —Johnson is one of the first doctors to perform the treatment. Orthobiologics ...
(Date:6/24/2016)... ... June 24, 2016 , ... Those who have experienced traumatic ... many turn to unhealthy avenues, such as drug or alcohol abuse, as a coping ... released tools for healthy coping following a traumatic event. , Trauma sufferers tend to ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 2016 The Academy of Managed Care Pharmacy ... that would allow biopharmaceutical companies to more easily share ... formulary and coverage decisions, a move that addresses the ... The recommendations address restrictions in the sharing ... drug label, a prohibition that hinders decision makers from ...
(Date:6/24/2016)... 2016   Pulmatrix, Inc ., (NASDAQ: ... drugs, announced today that it was added to the ... its comprehensive set of U.S. and global equity indexes ... important milestone for Pulmatrix," said Chief Executive Officer ... our progress in developing drugs for crucial unmet medical ...
(Date:6/23/2016)... BEVERLY HILLS, Calif. , June 23, 2016 ... faced the many challenges of the current process. Many of ... option because of the technical difficulties and high laboratory costs ... would have to offer it at such a high cost ... to afford it. Dr. Parsa Zadeh , ...
Breaking Medicine Technology: