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Gene Linked to Form of Parkinson's Disease
Date:3/21/2008

t two genes known to be a common contributor to the disease, which has no known cause or cure and affects as many as one million Americans.

They noted that less than one-quarter of all Parkinson's cases are familial. But findings about genes like GIGYF2 could improve understanding of the mechanisms behind Parkinson's and may help lead to new treatments for all forms of the disease, the researchers said.

They also identified a possible association between Parkinson's and insulin and the related growth hormone called insulin-like growth factor (IGF). This adds to a growing body of research linking insulin and IGF to Parkinson's, Alzheimer's and other neurodegenerative diseases.

"A better understanding of the link between insulin or IGF and Parkinson's may lead us to new treatment strategies for Parkinson's and also new insights into the connection between diabetes and nervous system disorders," Smith said.

More information

We Move has more about Parkinson's disease.



-- Robert Preidt



SOURCE: Brown University, news release, March 20, 2008


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