Navigation Links
Gene Linked to Form of Parkinson's Disease
Date:3/21/2008

Finding could lead to better understanding of the incurable neurological disorder

FRIDAY, March 21 (HealthDay News) -- Mutations in a gene called GIGYF2 may be directly linked to the development of Parkinson's disease in families with a history of the neurodegenerative condition, U.S. researchers report.

"These findings may ultimately help open the door to the development of new therapeutic -- and possibly even preventive -- strategies that target the underlying cause of Parkinson's disease, improving quality of life of the many people worldwide who are affected by this devastating disorder," senior author Dr. Robert J. Smith, professor of medicine at the Warren Alpert Medical School of Brown University, said in a prepared statement.

His team analyzed DNA samples from 249 Parkinson's patients with at least one first-degree relative (parent, child, sibling) with the disease, and compared them to DNA samples from 200 healthy people.

The researchers found that GIGYF2 resides on a chromosomal region called PARK11, which is linked to Parkinson's.

"Our data provides strong support for GIGYF2 as a PARK11 gene with a casual role in familial Parkinson's disease," said Smith, who is also director of the division of endocrinology and the Hallett Center for Diabetes and Endocrinology at Rhode Island Hospital.

"The next step is to zero in on this gene to learn more about its involvement in triggering Parkinson's. It will also be important to evaluate additional and larger families with Parkinson's and these genetic mutations, as well as the frequency of GIGYF2 mutations in patients with the more common, idiopathic form of the disease," he said.

The study appears online in the American Journal of Human Genetics and will be published in the April 11 print issue of the journal.

Smith and his colleagues said GIGYF2 is one of only a few genes so far linked to Parkinson's and one of jus
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Pot bellies linked to early signs of cardiovascular disease
2. Diet high in meat, fat and refined grains linked to risk for colon cancer recurrence, death
3. Immune deficiency linked to a type of eye cancer
4. Drop in breast cancer incidence linked to hormone use, not mammograms
5. Clinical depression linked to abnormal emotional brain circuits
6. Air pollution linked to cardiovascular risk indices in healthy young adults
7. High pollution linked to poor lung function growth in children in Mexico City
8. Early Weight Loss in Women Linked to Dementia
9. Vitamin Es lack of heart benefit linked to dosage
10. Sugary Sodas High in Diabetes-Linked Compound
11. RA Drugs Linked to Slight Skin Cancer Risk
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Gene Linked to Form of Parkinson's Disease
(Date:11/22/2014)... November 22, 2014 Lipitor lawsuits ( ... patients who allegedly developed Type 2 diabetes due to ... multidistrict litigation now underway in U.S. District Court, District ... court documents, the litigation will convene its next Status ... has directed Lead Counsel for Plaintiffs and Defendants to ...
(Date:11/22/2014)... Recently, UWDress.com is gratified to introduce ... . In addition, the company has also offered an ... a leading online supplier of wedding dresses, UWDress.com is ... unusual best wedding guest gowns are provided over 20 ... this new selection is famous for high quality. Therefore, ...
(Date:11/22/2014)... Sandbridge Capital, a private equity firm ... brand sector, acquired a minority stake in BackJoy ... help fund BackJoy’s global growth and accelerate the ... apparel and footwear lines. Sandbridge Capital Managing Partner ... , BackJoy is a high-growth health and wellness ...
(Date:11/22/2014)... 2014 “Greenfield Naturals” was featured on ... , which features the latest and coolest technology products ... reporter for NewsWatch, conducted the product review and shared ... of your water. , From pollution to hazardous substances ... everything is done to remove these chemicals, especially in ...
(Date:11/22/2014)... 21, 2014 (HealthDay News) -- A clinical trial of ... been halted a year early because the results show ... the disease and reduce the risk of stroke. ... 25 medical centers in the United States and Canada, ... Lung, and Blood Institute (NHLBI). Researchers compared monthly ...
Breaking Medicine News(10 mins):Health News:Lipitor Lawsuit Conference Scheduled for December, Bernstein Liebhard LLP Reports 2Health News:Lipitor Lawsuit Conference Scheduled for December, Bernstein Liebhard LLP Reports 3Health News:Best Wedding Guest dresses Introduced by UWDress.com 2Health News:Sandbridge Capital Acquires a Minority Stake in BackJoy 2Health News:Sandbridge Capital Acquires a Minority Stake in BackJoy 3Health News:An Easy Home Solution to Get Better Tasting Water was Featured on NewsWatch Television on October 30, 2014 2Health News:Sickle Cell Anemia Treatment So Successful in Kids That Trial Is Halted 2
... 4, 2008 Bayada Nurses will hold,a news conference ... and the,public about the importance of raising the Medicaid ... health care, and allow more,individuals to benefit from the ... 190,000 Pennsylvanians use home health care services each,week -- ...
... Receives National Award for Arming Oncologists, Families and ... 2008 When the,critically acclaimed A LION IN ... the film galvanized public attention for childhood cancer ... their families. Now,LION,s producers are being honored in ...
... ARBOR, Mich.---Having a husband creates an extra seven hours a ... Michigan study of a nationally representative sample of U.S. families. ... saves men from about an hour of housework a week. ... housework trends, based on 2005 time-diary data from the federally-funded ...
... Study by New York,s premier dermatologist, Dr. David J. ... first ... 4, 2008 Aesthetic Technologies,announced during the 28th Annual ... Kissimmee, Fla., the introduction of its,Parisian Peel(R) Suffusion System. ...
... Donation Will Be Made to Middle Island Man, 32, Injured ... 4, 2008 The,following was released by The SCOOTER Store:, ... New York,City patrolman and Suffolk County parks policeman, John ... Tim Bishop (NY - 1st District), Suffolk County Legislator ...
... Ohio) More than 600,000 children participate in school-sponsored ... Yet gymnastics continues to be overlooked in terms of ... injury rates of all girls sports. , A study, ... and Policy (CIRP) at The Research Institute at Nationwide ...
Cached Medicine News:Health News:Acclaimed A LION IN THE HOUSE Team Honored in Washington for Pioneering Work on Pediatric Cancer 2Health News:Acclaimed A LION IN THE HOUSE Team Honored in Washington for Pioneering Work on Pediatric Cancer 3Health News:Exactly how much housework does a husband create? 2Health News:Parisian Peel(R) Introduces Anti-Aging Suffusion System 2Health News:Parisian Peel(R) Introduces Anti-Aging Suffusion System 3
(Date:11/21/2014)... , Nov. 20, 2014 /CNW Telbec/ - KLOX ... announce the following appointments: Todd ... in the newly created role of Chief Commercial Officer, ... system using topical photoconverter gel for the treatment of ... and traumatic wounds, recently approved in Europe ...
(Date:11/21/2014)... Michael DeMarco (42) erinnert sich ... Februar 2014 zugetragen hat. Seine Tochter Aly Demarco (13) ... Video - http://youtu.be/5cVoMCe0uiE „Man ... Training zu machen", erzählt Michael DeMarco . „Meine ... begeisterte Anhänger der CrossFit-Trainingsmethode. Ich war auf dem Fahrrad, ...
(Date:11/21/2014)... , Nov. 20, 2014   Coqui RadioPharmaceuticals Corp. ... first U.S. commercial producer of Molybdenum-99 (Mo-99), is proud ... INVAP to design its Medical Isotope Production ... Mo-99 is the parent isotope of Technetium-99, which is ... In 2012, Congress passed legislation making it a national ...
Breaking Medicine Technology:KLOX Technologies announces executive appointments 2KLOX Technologies announces executive appointments 3KLOX Technologies announces executive appointments 4Tochter rettet Vater durch Herz-Lungen-Wiederbelebung vor plötzlichem Herztod 2Tochter rettet Vater durch Herz-Lungen-Wiederbelebung vor plötzlichem Herztod 3Coqui RadioPharmaceuticals Inks Deal With INVAP 2
... BETHESDA, Md., May 25, 2011 Northwest Biotherapeutics (OTC.BB: ... of clinical trial sites, exceeding its projections for the ... quarter, for enrollment of new patients into the Company,s ... of DCVax® immune therapy for Glioblastoma multiforme (GBM), the ...
... 25, 2011 Executives from Medco Health Solutions, Inc. (NYSE: ... investor conferences: Timothy Wentworth, Group President, Employer and ... Strategic Decisions Conference on Wednesday, June 1 at 10 a.m. ... New York.  Richard J. Rubino, Medco,s chief financial officer, is ...
Cached Medicine Technology:Northwest Biotherapeutics Further Expands Ongoing Brain Cancer Trial 2Northwest Biotherapeutics Further Expands Ongoing Brain Cancer Trial 3Medco Executives to Present at Upcoming Investor Conferences 2
Dissecting Forceps, straight, with RF-cable, 7" (18 cm). For use with all electrosurgical generators with standard three-prong sockets....
... the art in inverted microscopy from Zeiss. ... range of ICS objectives, with innovative condensers ... an unusual scope of sophisticated documentation and ... designed. And Axiovert 200 M, fully motorized, ...
... optics and workmanship are the hallmark of ... sensitivity in mind. The top (incident) circular ... eliminating shadows while remaining cool to the ... available with 10x to 44x zoom magnification ...
... system designed for scientific microscope imaging ... cameras provides high-resolution, full-color images and ... PC via its Firewire (IEEE 1394) ... is accompanied by automatic white balance ...
Medicine Products: