Navigation Links
Gene Fusions May Drive Certain Cancers
Date:1/12/2009

Prostate cell findings could reveal targets for future treatments

MONDAY, Jan. 12 (HealthDay News) -- Researchers say they have discovered genes in prostate cancer cells that fuse when their chromosomes trade places with each other, an occurrence that may initiate the development of some cancers.

The mutations, identified by researchers at the University of Michigan Comprehensive Cancer Center, appear only in cancer cells, a finding that may serve as a marker for diagnosing cancer or a target for future treatment drugs. Some of the fusions appeared in multiple cell lines, but others were unique.

"The recurrent fusions are thought to be the driving mechanism of cancer. But we found other fusions as well, some of which were unique to individual patients. Our next step is to understand if these play a role in driving disease," Dr. Arul Chinnaiyan, the S.P. Hicks-endowed professor of pathology at the U-M Medical School, said in a university news release.

Gene fusions were known to occur in blood cell cancers, such as leukemia and lymphoma, but these are the first to be found in prostate cancer.

The findings, published in Nature, are also important because they made use of faster, more efficient gene-sequencing technology. This requires developing a library of all a cell's RNAs that researchers can study for fusions.

The researchers are now studying gene fusions involved in breast cancer, lung cancer and melanoma.

More information

The U.S. National Institute of Cancer has more about prostate cancer.



-- Kevin McKeever



SOURCE: University of Michigan Health System, news release, Jan. 11, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Controversial Anemia Drug Doesnt Cut Need for Transfusions
2. Study links blood transfusions to surgery complications in women
3. Children with sickle cell disease, silent strokes show some relief with blood transfusions
4. Transfusions of Older Blood Dont Work as Well
5. Cell Fusions During Inflammation May Protect Neurons
6. Fresh Transfusions Improve Odds for Cancer Patients After Surgery
7. Transfusions increase clot risk in hospitalized cancer patients
8. Virus Could Help Drive Obesity
9. Back to School Means Return of School Blood Drives
10. Expanding Prevalent Population Will Drive Dramatic Growth for the Asthma Drug Market in China
11. End-to-End HR Performance Benchmarks: Metrics That Will Help Turn the HR Cost Center into a Productivity Driver
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Gene Fusions May Drive Certain Cancers
(Date:3/3/2015)... Mercy Health (formerly Catholic Health Partners) – a Catholic healthcare ... of its monthly Mercy Health: Helping You Be Well videos ... disorders in the United States, affecting an estimated 16 million ... Mercy Health’s YouTube channel , Mercy Health experts explain ... you can help someone with the illness get the help ...
(Date:3/3/2015)... March 03, 2015 The physicians at ... fast weight loss product that is being recommended by ... because it contains ingredients that help people lose weight ... new combination diet product thought to possess innovative solutions ... contains three ingredients, all directed at targeting specific strategic ...
(Date:3/3/2015)... March 03, 2015 The Forbes ... covers some great ideas when planning an Eco-vacation. It ... an environmentally friendly approach. The segment will explore the ... hotel or resort’s sustainability policy, request Earth-friendly choices along ... remind viewers about how to save electricity while away. ...
(Date:3/3/2015)... March 03, 2015 First Choice ... emergency rooms in the United States, named Jeffrey Lynn ... Louetta facility. , “We are pleased to announce ... our Louetta facility,” said Dr. James M. Muzzarelli, Executive ... Dr. Smaistrla received his undergraduate and medical degrees from ...
(Date:3/3/2015)... 2015 When a lifeguard is on duty, it ... is more than just loose clothing. For a lifeguard, comfort ... public too much when the guard prefers to cover up. Comfort ... the evening and wearing the clothing that fits correctly. When ... shift, it is imperative that the guard stays warm and comfortable ...
Breaking Medicine News(10 mins):Health News:New Videos Tackle Widespread Problem of Depression 2Health News:Diet Doc Discloses the Ingredients in their Powerful New Metabolism Boost for Controlled Appetite, Fast Weight Loss and Improved Mood 2Health News:Diet Doc Discloses the Ingredients in their Powerful New Metabolism Boost for Controlled Appetite, Fast Weight Loss and Improved Mood 3Health News:Diet Doc Discloses the Ingredients in their Powerful New Metabolism Boost for Controlled Appetite, Fast Weight Loss and Improved Mood 4Health News:Forbes Living Segment on Planning an Eco-Vacation in the Works 2Health News:First Choice Emergency Room Announces Dr. Jeffrey Smaistrla as New Medical Director of LouettaFacility 2Health News:New Lifeguard Pants Introduced for those Colder Lifeguarding Days 2Health News:New Lifeguard Pants Introduced for those Colder Lifeguarding Days 3Health News:New Lifeguard Pants Introduced for those Colder Lifeguarding Days 4
... , , PRINCETON, N.J., July ... injection) can now use the insulin in their pump for ... Administration (FDA) approval of a labeling change, diabetes care company ... to be stored in the pump reservoir for two days. ...
... vaccine might fight ,tangles, of disease , WEDNESDAY, July ... two different types of brain abnormalities, both of which ... disease. , A drug called Dimebon seems to improve ... research reveals, it actually increases brain levels ...
... China, July 15 /PRNewswire-FirstCall/ - Hard to Treat Diseases ... is now preparing for the tender business of 250,000 ... and details can be viewed by visiting this web ... second completed batch exported to Indonesia this year by ...
... survey finds 3.3 percent of children aged 2 to 19 ... -- The number of underweight children aged 2 to 19 ... to 3.3 percent in 2003-2006, says a U.S. government study. ... health problems. , Researchers at the U.S. Centers for Disease ...
... , , DALLAS, July ... and practice management (PM) systems for medical practices, is now ... , , "Another company had established a ... was in place," noted Michael Nissenbaum, President and CEO of Aprima. "In ...
... cardiomyopathy , WEDNESDAY, July 15 (HealthDay News) -- Gene ... failure in some children and adults with dilated cardiomyopathy ... the most common cause of heart failure in young ... transplant -- is a condition in which the heart ...
Cached Medicine News:Health News:FDA Approves NovoLog(R) Labeling Update 2Health News:FDA Approves NovoLog(R) Labeling Update 3Health News:FDA Approves NovoLog(R) Labeling Update 4Health News:New Treatments for Alzheimer's on the Horizon 2Health News:New Treatments for Alzheimer's on the Horizon 3Health News:Hard To Treat Diseases (HTDS.PK) Tender Order To Indonesia 2Health News:'Aprima Medical Software, Inc.,' Unveiled by iMedica; Premier EHR / PM Company Adopts New Name 2Health News:'Aprima Medical Software, Inc.,' Unveiled by iMedica; Premier EHR / PM Company Adopts New Name 3Health News:Gene Mutation Is Linked to Heart Muscle Disease 2
(Date:3/3/2015)... and MENLO PARK, Calif. , ... DMPI) (DelMar and the Company), a biopharmaceutical company focused on ... indications, today announced that it will be presenting at the ... 2015, at The Ritz-Carlton, Laguna Niguel , ... Jeffrey Bacha , DelMar,s president and CEO, will ...
(Date:3/3/2015)... Calif. , March 3, 2015  STAAR Surgical Company ... marketer of implantable lenses and delivery systems for the eye, ... Officer effective immediately.  Ms. Mason, who was elected to STAAR,s ... the Board to chair the Quality and Regulatory Committee in ... as of March 1, 2015.  Ms. Mason ...
(Date:3/3/2015)... China Nepstar Chain Drugstore Ltd. (NYSE: ... drugstore chain in China based on the number of directly operated ... unaudited financial results for the fourth quarter and fiscal ... opens. The Company will host a ... 30, 2015 at 8:00 a.m. Eastern Time / 8:00 ...
Breaking Medicine Technology:DelMar Pharmaceuticals to Present at the 27th Annual ROTH Conference on March 10, 2015 2DelMar Pharmaceuticals to Present at the 27th Annual ROTH Conference on March 10, 2015 3Caren Mason Appointed President & CEO of STAAR Surgical Company 2Caren Mason Appointed President & CEO of STAAR Surgical Company 3Caren Mason Appointed President & CEO of STAAR Surgical Company 4Caren Mason Appointed President & CEO of STAAR Surgical Company 5China Nepstar Chain Drugstore to Report Fourth Quarter and Fiscal Year 2014 Financial Results on March 30, 2015 2China Nepstar Chain Drugstore to Report Fourth Quarter and Fiscal Year 2014 Financial Results on March 30, 2015 3
... Bionovo, Inc. (Nasdaq: BNVI ), a pharmaceutical company ... treatments for women,s health and cancer, today announced that Dr. ... presenting at the Cowen and Company 31st Annual Healthcare Conference ... event will be held at the Boston Marriott Copley Place, ...
... (OTCQB: CTIX) today reported that its flagship cancer compound, ... of leukemia cells in a hematopoietic xenograft tumor model. ... of p53, the "Guardian Angel" protein, which Cellceutix announced ...   The data was presented to Cellceutix ...
Cached Medicine Technology:Bionovo to Present at the Cowen and Company 31st Annual Healthcare Conference 2Cellceutix Discovers Drug Activates 'Guardian Angel p53' in Fight Against Leukemia 2Cellceutix Discovers Drug Activates 'Guardian Angel p53' in Fight Against Leukemia 3
5 mm concave jaws, cross action....
... inserter is the first of its kind. ... through a minimal incision. The special direct-acting ... bag with complete control and predictability. The ... easy around-the-clock, and the instrument has a ...
... AMO SI-30 and SI-40 foldable lenses through incisions ... for clear corneal and corneal scleral tunnels. The ... millimeter rounded blades for a secure grasp of ... have a .15 millimeter notch which may be ...
KR-8000 Supra is capable of obtaining perfectly accurate keratometry and/or refraction measurements through pupils as narrow as 2.0 mm....
Medicine Products: