Navigation Links
Gene Discovery Sheds Light on Children's Asthma
Date:12/23/2009

Scientists find 2nd piece of DNA tied to the respiratory illness, experts say

WEDNESDAY, Dec. 23 (HealthDay News) -- A new gene involved in immune system function has been linked to moderate-to-severe childhood asthma.

Identification of the specific mutation may one day lead to new targets for treating the widespread and troublesome illness, researchers report in the Jan. 7 issue of the New England Journal of Medicine.

Still, any one gene is likely just a piece of the asthma puzzle, one expert cautioned.

"There are only a handful diseases for which the problem is a single gene, for example, cystic fibrosis. And even those are complex with numerous mutations on that gene," said Dr. Norman Edelman, chief medical officer for the American Lung Association. "Asthma clearly is not a single gene problem. This is good work. They know what the gene codes for but it doesn't mean we're any closer to a cure."

Asthma can likely be attributed to environmental and genetic factors and an interaction between the two, but most of the genes implicated in asthma are still unknown.

One 2007 study used genome-wide association methods to identify ORMLD3 on chromosome 17, the only other gene so far related to asthma risk.

"That gene did not have a hugely significant effect," noted Dr. Hakon Hakonarson, director of the Center for Applied Genomics at Children's Hospital of Philadelphia (CHOP) and the senior author of the new study.

That indicates that probably no one gene will account for the lion's share of asthma. "The 2007 paper would have seen that if that was the case," Hakonarson said.

These researchers used the same methodology -- a genome-wide association study -- to study the genetics of 793 white children with persistent asthma, all patients at CHOP. The team then compared that data to the genetics of almost 2,000 healthy children.

The group of children with
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Discovery of sugar sensor in intestine could benefit diabetes
2. Discovery suggests location of genes for breast density, a strong risk factor for breast cancer
3. Stem cell research produces a key discovery for Fragile X Syndrome
4. Welch Foundation gives $1.6 million for drug discovery research
5. New discovery leaves blood-doping athletes scratching their heads
6. Chemical Diversity Initiates International Prostrate Cancer Discovery Partnership
7. New discovery leaves blood-doping athletes scratching their heads
8. Discovery of widespread tumor growth gene holds promise for effective anti-cancer treatment
9. Discovery supports theory of Alzheimers disease as form of diabetes
10. Discovery Health CME Explores the Benefits and Risks of Aspirin in Aspirin Therapy: Maximizing the Benefits
11. New discovery may improve treatment of one of the worlds leading causes of blindness
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/25/2014)... New York, New York (PRWEB) October 25, 2014 ... lawsuits ( http://www.thexareltolawsuit.com/ ) will be addressed in December, ... convenes its next hearing session. According to a Hearing ... Oral Arguments on the matter will be heard on ... Session will begin at 9:30 a.m. (In Re: Xarelto ...
(Date:10/25/2014)... Madison, WI (PRWEB) October 25, 2014 ... of tax-advantaged medical and other benefits account management ... designed to help employers save on taxes, reduce ... new Suites provide tax savings and the efficient ... can pick the Suite that best meets their ...
(Date:10/25/2014)... (PRWEB) October 25, 2014 The ... ( http://www.vaginalmeshlawsuit2015.com/ ) filed against Boston Scientific ... U.S. District Court, Southern District of West Virginia ... on Punitive Damages in a group of cases ... ruling issued on October 21st, U.S. District Judge ...
(Date:10/25/2014)... -- Not getting the right amount of sleep might ... suggests. Those who sleep less or more than ... be more prone to developing the chronic condition, which ... authors concluded that duration and quality of sleep are ... bowel diseases. "Both short and long durations of ...
(Date:10/25/2014)... 2014 (HealthDay News) -- October,s shorter, darker days can ... disorder, according to an expert. People affected ... overly tired, lack motivation and even have trouble getting ... to suicide, said Dr. Angelos Halaris, a professor in ... University Chicago Stitch School of Medicine. "Seasonal affective ...
Breaking Medicine News(10 mins):Health News:Xarelto Lawsuit News: JPML to Hear Oral Arguments on Proposed Xarelto Multidistrict Litigation at December Hearing, Bernstein Liebhard LLP Reports 2Health News:Xarelto Lawsuit News: JPML to Hear Oral Arguments on Proposed Xarelto Multidistrict Litigation at December Hearing, Bernstein Liebhard LLP Reports 3Health News:TASC’s New Suites Offer Tax Savings and Protection 2Health News:Transvaginal Mesh Lawsuits Move Forward, As Federal Judge Denies Motion for Summary Judgment on Punitive Damages in Florida Cases, Bernstein Liebhard LLP Reports 2Health News:Transvaginal Mesh Lawsuits Move Forward, As Federal Judge Denies Motion for Summary Judgment on Punitive Damages in Florida Cases, Bernstein Liebhard LLP Reports 3Health News:Transvaginal Mesh Lawsuits Move Forward, As Federal Judge Denies Motion for Summary Judgment on Punitive Damages in Florida Cases, Bernstein Liebhard LLP Reports 4Health News:Sleep Duration Linked to Ulcerative Colitis Risk in Study 2Health News:Dark Days Here for Folks With Seasonal Depression 2
... Successful, OWINGS MILLS, Md., Oct. 4 Medifast, ... the current business outlook, the,Company is updating full year ... expects to report revenue of $81 to $83 million ... Previously, the Company,expected to report revenue of $85 to ...
... just part of what is ... local nonprofit for teens., WILSONVILLE, Ore., Oct. 4 On Tuesday, ... in furniture,arcade games and supplies. These and other items, unused for at ... to the,Sexual Minority Youth Resource Center (SMYRC). Volunteer crews will move ...
... - A new American Heart,Association survey (1) shows consumer awareness of the ... high. But consumers still need,some key information to improve how they eat., ... Fats Are The survey shows that:, --While 92 percent of ... jump from 84 percent in 2006 - only 21 percent can name ...
... revealing how toxic chemicals disrupt gene activity and other ... -- and why some individuals are particularly vulnerable. For ... more likely to experience side effects from certain medications, ... , How can this type of research -- known ...
... 22 new centers now added, first participants set to join ... -- The largest study ever of the impact of environment ... directed from 22 new centers across the United States, organizers ... first participants enrolled in the National Children,s Study should be ...
... president and CCO of,KickSkirt, Inc., will lead a ... the health of their children while also improving ... The Marketing-To-Moms Conference,October 23-24, 2007, Chicago Cultural Center. ... and medical director of Peak Wellness and star ...
Cached Medicine News:Health News:Medifast Announces Updated Full Year 2007 Guidance 2Health News:Medifast Announces Updated Full Year 2007 Guidance 3Health News:Medifast Announces Updated Full Year 2007 Guidance 4Health News:Contents of the McGinnis Mansion Refurbishes Portland, Oregon Sexual Minority Youth Center 2Health News:Contents of the McGinnis Mansion Refurbishes Portland, Oregon Sexual Minority Youth Center 3Health News:Americans' Knowledge of Fats Growing But Still Insufficient 2Health News:Americans' Knowledge of Fats Growing But Still Insufficient 3Health News:Largest Study of U.S. Children Readies for Launch 2Health News:Brands Tackle the Childhood Obesity Issue During M2Moms(TM) - The Marketing-To-Moms Conference 2
(Date:10/22/2014)... Oct 22, 2014 Antigen Discovery Inc. (ADi), ... , announced the receipt of a National Institutes ... (SBIR) from the National Institute of Dental and Craniofacial Research ... of a Pan-HIV Protein Microarray Chip, which will contain ... subtypes and aid in the development of safe and ...
(Date:10/22/2014)... , Oct. 22, 2014  Paper Pak ... has developed APLS ® Body Guard Bio, ... the spread of bacteria and virus while protecting ... Body Guard Bio features a rugged, external nylon ... that create a leak-proof inner chamber that contains ...
(Date:10/22/2014)... YARDLEY, Pa. , Oct. 22, 2014 /PRNewswire/ ... of their animal health medications, a Global Pharmaceutical ... and Antares serialization technology and turnkey solution to ... Photo - http://photos.prnewswire.com/prnh/20141021/153438 ... The product that was serialized and aggregated by ...
Breaking Medicine Technology:Biomarker Discovery Company, Antigen Discovery Inc., Awarded an NIH Phase I Small Business Innovation Research Grant to Develop a Pan-HIV Protein Microarray Chip 2New, State-Of-The-Art Body Bag Minimizes The Spread Of Bacteria And Virus 2Xyntek and Antares Serialization Solution Protects Pets Too! 2
... Ga., June 13, 2011 Friends of Disabled Adults and ... IVC ), providing immediate aid shipments of equipment and supplies ... center of Joplin on May 22, 2011, leaving much of ... was able to send the first supply shipment to Joplin ...
... 2011 Chicago based Share Your Soles marked its twelfth ... celebration for Mona Purdy, Founder of Share Your Soles, but ... to those in need in just over a decade. ... events that provide the necessary support to putting shoes on ...
Cached Medicine Technology:Friends of Disabled Adults and Children Partners With Invacare to Provide Aid in Wake of Joplin Tornado 2Friends of Disabled Adults and Children Partners With Invacare to Provide Aid in Wake of Joplin Tornado 3Chicago Based Share Your Soles Expanding to Become Global Shoe Donation Leader 2
For the qualitative detection of Hepatitis B surface Antigen (HBsAG) in human serum, plasma and whole blood specimens...
For the qualitative detection of luteinising Hormone (LH) in urine specimens...
For the qualitative detection of luteinising Hormone (LH) in urine specimens...
For the qualitative detection of group A Streptococcal antigen from throat swabs...
Medicine Products: