Navigation Links
Gene Discovery Sheds Light on Children's Asthma
Date:12/23/2009

Scientists find 2nd piece of DNA tied to the respiratory illness, experts say

WEDNESDAY, Dec. 23 (HealthDay News) -- A new gene involved in immune system function has been linked to moderate-to-severe childhood asthma.

Identification of the specific mutation may one day lead to new targets for treating the widespread and troublesome illness, researchers report in the Jan. 7 issue of the New England Journal of Medicine.

Still, any one gene is likely just a piece of the asthma puzzle, one expert cautioned.

"There are only a handful diseases for which the problem is a single gene, for example, cystic fibrosis. And even those are complex with numerous mutations on that gene," said Dr. Norman Edelman, chief medical officer for the American Lung Association. "Asthma clearly is not a single gene problem. This is good work. They know what the gene codes for but it doesn't mean we're any closer to a cure."

Asthma can likely be attributed to environmental and genetic factors and an interaction between the two, but most of the genes implicated in asthma are still unknown.

One 2007 study used genome-wide association methods to identify ORMLD3 on chromosome 17, the only other gene so far related to asthma risk.

"That gene did not have a hugely significant effect," noted Dr. Hakon Hakonarson, director of the Center for Applied Genomics at Children's Hospital of Philadelphia (CHOP) and the senior author of the new study.

That indicates that probably no one gene will account for the lion's share of asthma. "The 2007 paper would have seen that if that was the case," Hakonarson said.

These researchers used the same methodology -- a genome-wide association study -- to study the genetics of 793 white children with persistent asthma, all patients at CHOP. The team then compared that data to the genetics of almost 2,000 healthy children.

The group of children with
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Discovery of sugar sensor in intestine could benefit diabetes
2. Discovery suggests location of genes for breast density, a strong risk factor for breast cancer
3. Stem cell research produces a key discovery for Fragile X Syndrome
4. Welch Foundation gives $1.6 million for drug discovery research
5. New discovery leaves blood-doping athletes scratching their heads
6. Chemical Diversity Initiates International Prostrate Cancer Discovery Partnership
7. New discovery leaves blood-doping athletes scratching their heads
8. Discovery of widespread tumor growth gene holds promise for effective anti-cancer treatment
9. Discovery supports theory of Alzheimers disease as form of diabetes
10. Discovery Health CME Explores the Benefits and Risks of Aspirin in Aspirin Therapy: Maximizing the Benefits
11. New discovery may improve treatment of one of the worlds leading causes of blindness
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/20/2014)... San Diego, CA (PRWEB) October 20, 2014 ... regarding all the latest information from the FDA on ... consumers on October 10 not to purchase or use Sit ... Phenolphthalein. Sit and Slim II is promoted as weight loss ... , Sibutramine, removed from the market in 2010 for safety ...
(Date:10/20/2014)... National Teen Driver Safety Week is October 19-25, ... Pediatrics (Ohio AAP, http://www.ohioaap.org ) is joining the National ... drivers to talk to their teens and always set the ... are the leading cause of death for U.S. teens. In ... and 859 (42%) of those teen drivers were killed in ...
(Date:10/20/2014)... Houston, Texas (PRWEB) October 20, 2014 ... invited to present the key elements of his innovative ... visiting professor to plastic surgery residents and faculty at ... (UTMB) , where he, too, was once a medical ... of the largest private cosmetic plastic surgery practices in ...
(Date:10/19/2014)... 2014 Dr. Babatunde Osotimehin, Executive Director ... of a ceasefire agreement that is expected to lead ... who were kidnapped from the north-eastern Nigerian town of ... long enough, and it is high time they are ... Osotimehin. , "We owe it to these girls to ...
(Date:10/19/2014)... 20, 2014 SweetDressy.com, a professional company ... its promotion for long evening dresses . All ... special offer; the current discount is up to 66 ... industry pioneers in the fashion field. Its dress specialists ... dwelling in various parts of the world. All the ...
Breaking Medicine News(10 mins):Health News:FDA Advises Not to Use Sit and Slim II: AttorneyOne Monitors and Keeps Consumers Informed 2Health News:Ohio AAP Promotes National Teen Driver Safety Week 2Health News:Plastic Surgeon Patronella Presents Artistically-Inspired Tummy Tuck Method to Future Generation of Plastic Surgeons in Texas 2Health News:Promotion For Beautiful Long Evening Dresses Launched By SweetDressy.com 2
... better understand where to focus efforts to ... CAMBRIDGE, MA, May 28 /PRNewswire/ - rL ... software that helps organizations manage,infection control issues, patient ... claims and quality issues,announced today that Caritas Christi ...
... N.C., May 28 Take advantage of quick ... attend the 10th Annual Human,Resources Conference: Leadership Development ... full conference agenda at, http://www3.best-in-class.com/gr163.htm ), sponsored ... 2008, at The Ritz-Carlton,Hotel, Sarasota, Fla., Registration ...
... TV Leader Guthy-Renker Attracts yet Another Celebrity for ... America,s Best-Selling Acne ... announced,today that Ryan Sheckler, famed skateboarder and television star, ... acne treatment,Proactiv Solution. Known for its wide range of ...
... Million Home-Device Market With First-to-Market ... Technology, Strong Branding, ... series of corporate milestones in anticipation of FDA clearance,for CLARO, ... the appointment of a senior marketing,executive, expansion of the Board ...
... 28 Shamir Optical,Industry Ltd. (Nasdaq: SHMR ) ... the progressive ophthalmic lens market, today,announced unaudited financial results ... the quarter ended March 31, 2008, revenues increased 29.5% ... the same period of 2007.,Gross profit for the quarter ...
... LOS ANGELES, May 28 5-year-old Noor came to,the ... Division,s 1st,Battalion, 30th Infantry Regiment, 2nd Brigade Combat Team ... that resulted,in the death of the little girl,s uncle. ... battalion surgeon, concluded that Noor is blind,due to a ...
Cached Medicine News:Health News:Caritas Christi Standardizes on rL Solutions to Help Deliver Best in Class Healthcare Quality 2Health News:Registration Ends This Week: Fortune 500 Networking & Best Practice Sharing Conference in Florida 2Health News:Professional Skateboarder Ryan Sheckler to Become the Newest Face of Proactiv Solution 2Health News:Professional Skateboarder Ryan Sheckler to Become the Newest Face of Proactiv Solution 3Health News:CLRS Technology Accelerates Infrastructure Growth Anticipating FDA Clearance for At-Home IPL Acne Device 2Health News:CLRS Technology Accelerates Infrastructure Growth Anticipating FDA Clearance for At-Home IPL Acne Device 3Health News:Shamir Optical Industry Ltd. Reports First Quarter 2008 Results 2Health News:Shamir Optical Industry Ltd. Reports First Quarter 2008 Results 3Health News:Shamir Optical Industry Ltd. Reports First Quarter 2008 Results 4Health News:Shamir Optical Industry Ltd. Reports First Quarter 2008 Results 5Health News:Shamir Optical Industry Ltd. Reports First Quarter 2008 Results 6Health News:Shamir Optical Industry Ltd. Reports First Quarter 2008 Results 7Health News:Shamir Optical Industry Ltd. Reports First Quarter 2008 Results 8Health News:Shamir Optical Industry Ltd. Reports First Quarter 2008 Results 9Health News:Photos: Los Angeles Non Profit Teams With US Troops Stationed in Baghdad and Buaytha in Bringing a 5-Year-Old Blind Iraqi Girl, Whose Father Stands Beside US Combat Team Against Al Qaeda, to the US for a Groundbreaking Artificial Corneal Transplant Surger 2
(Date:10/17/2014)... --  ndd Medical Technologies , a leader in innovative ... announced that its EasyOne Pro® is now being used ... 140,000 square foot, 44-bed hospital with many outpatient services. ... a large number of Native Americans from several tribes ... beyond. A portion of its funding comes from the ...
(Date:10/17/2014)...  STAAR Surgical Company (NASDAQ: STAA ), a ... for the eye, today announced that the Company will webcast ... 18, 7:00 a.m. CT at the American Academy of Ophthalmology ... Dr. Erik Mertens , Medical Director and ... Belgium , will present his first cases with the ...
(Date:10/17/2014)... , October 17, 2014 People ... pharma companies. The challenge with this is that ... information with their competition. Putting this together was ... we,ve cracked it! We,ve asked big pharma companies to put ... their cold chain strategies - with one caveat - some ...
Breaking Medicine Technology:EasyOne Pro Mobile Respiratory Testing from ndd Medical Technologies Chosen by Choctaw Nation 2STAAR Surgical to Webcast Investor Presentations at American Academy of Ophthalmology's Annual Meeting 2STAAR Surgical to Webcast Investor Presentations at American Academy of Ophthalmology's Annual Meeting 3Pharma Cool Chain & CRT Benchmarking Report 2