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Gene Discoveries Could Shed New Light on Schizophrenia
Date:7/22/2014

mmune function. One site was even focused on a specific target for schizophrenia medication, the study revealed.

One association was confirmed with a variation in a gene that codes for a receptor for dopamine -- a brain chemical messenger that is a known target for drugs used to treat schizophrenia.

The researchers believe that even more genetic clues to schizophrenia could be uncovered in studies with even larger numbers of patients.

"These results underscore that genetic programming affects the brain in tiny, incremental ways that can increase the risk for developing schizophrenia," Thomas Lehner, chief of NIMH's Genomics Research Branch, said in the news release. "They also validate the strategy of examining both common and rare [gene] variation to understand this complex disorder."

The study was published online July 22 in Nature.

More information

The National Alliance on Mental Illness has more about schizophrenia.

SOURCE: U.S. National Institute of Mental Health, news release, July 21, 2014

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