Navigation Links
Gene Behind Gaucher Disease a Player in Parkinson's
Date:10/21/2009

Finding from worldwide study could one day lead to new treatments

WEDNESDAY, Oct. 21 (HealthDay News) -- An unprecedented worldwide study has clinched the case that the gene behind Gaucher disease, a rare neurological disorder, is also involved in Parkinson's disease.

"For those of us who work with rare disorders, it is heartwarming to come up with insights that are applicable to more common disorders," said Dr. Ellen Sidransky, a senior investigator in the U.S. National Human Genome Research Institute, and leader of a study reported in the Oct. 22 issue of the New England Journal of Medicine.

Gaucher disease affects no more than one in 100,000 people in most populations, with an estimated 5,400 cases in the United States. As many as 3 million to 4 million Americans are estimated to have Parkinson's disease.

Gaucher disease develops in people who have two defective copies of a gene designated GBA. It codes for production of an enzyme that breaks down glucocerebrosidase, a fatty substance normally found in the body. The faulty gene allows accumulation of the substance, which can harm the spleen, liver, lungs, bone marrow and even the brain.

Discovery that the two conditions have a common genetic element cannot be applied immediately to relieve the stiffness, trembling and other symptoms of Parkinson's disease, Sidransky said.

"We have to be cautious about jumping into clinical applications," she said. "This gene plays a more common role in Parkinson's than other genes, but it is not necessarily predictive of Parkinson's disease. It is a risk factor rather than a gene that predicts the disease."

"The work will teach us about the mechanisms of Parkinson's disease, and once we understand the mechanisms we can come up with therapies that can help patients with Parkinson's disease. And it could ultimately lead to better therapies that could help patients with Gaucher disease," Sidrans
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Genes behind increasingly common form of cancer identified
2. Producers of New PBS Series Joined By Experts to Reveal Science Behind Happiness
3. Max Muscle Franchising Is Fueled By The Passion Behind The Brand
4. Brain Training Keeps Older Drivers Safe Behind the Wheel
5. Innovative New Book Series Encourages Kids to Go Behind Their Parents' Backs and Listen to Experts on Important Health and Wellness, Education, Personal Finance and Nutrition
6. Leave Worries Behind When Packing for Vacation
7. Researchers Discover the Tale Behind Short Dogs
8. Mylan Reiterates and Stands Behind Its 48-Year Commitment and Track Record of Quality
9. Michael Jackson Get the Medical Facts Behind the Headlines at CelebrityDiagnosis.com
10. Is Your Teenager Using Prescription Drugs Behind Your Back? TestCountry Drug Test Panel Numbers Tally with NIDA Fact Sheet Reports on Prescription Drug A
11. Businesses, Unions, Veteran Party Leaders Unite Behind Bipartisan, Consensus Approach to Health Care Reform
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2014)... University,s Center for Leadership in Disability (CLD) has ... and Child Health Bureau of the Health Resources ... Autism Plan for Georgia, aimed at improving services ... , In preparing for this project, CLD worked ... stakeholders from across Georgia. The resulting plan addresses ...
(Date:8/27/2014)... Angeles, CA (PRWEB) August 27, 2014 Jaha ... To do this, Jaha invested in creating the industry’s most ... by adding functions that no other apps possess. ... a tracker that differentiates in three simple steps: locate, challenge ... launch on Tuesday, Aug 26, 2014 to garner support and ...
(Date:8/27/2014)... Cash House 's contributions to Horizons ... upkeep of the shelter including new initiatives and a wide ... the lives of each youth who walk through their door. ... for youth ages 16-25. Not only does Horizons operate as ... for the youth who come through their doors. Horizons has ...
(Date:8/27/2014)... The Global and China Maleic Anhydride Industry is ... of the Maleic Anhydride industry in Global and China. ... industry, including definitions, applications and industry chain structure. Global ... with a focus on history, developments, trends and competitive ... and Chinese situation is also offered. Get a copy ...
(Date:8/27/2014)... Many patients believe mental illness is not life ... mortality rate of about 15%. The suicide rate ... it's offset by an alarming homicide rate (including attempted ... treat and manage symptoms of mental illnesses like depression, ... directed. Missed dosages or cutting pills in half ...
Breaking Medicine News(10 mins):Health News:Jaha, Inc. The Most Affordable Fitness Band in the Market Released on Kickstarter 2Health News:Cash House a Major Supporter of Horizons for Youth 2Health News:Cash House a Major Supporter of Horizons for Youth 3Health News:Maleic Anhydride Industry & Isoprene Market Global and China Analysis Now Available at ReportsnReports.com 2Health News:Maleic Anhydride Industry & Isoprene Market Global and China Analysis Now Available at ReportsnReports.com 3Health News:Maleic Anhydride Industry & Isoprene Market Global and China Analysis Now Available at ReportsnReports.com 4Health News:Maleic Anhydride Industry & Isoprene Market Global and China Analysis Now Available at ReportsnReports.com 5Health News:MedicationDiscountCard.com now Makes Brintellix and Mental Illness Medications More Affordable with Discount Cards 2
... capable of detecting minute numbers of circulating,cancer cells ... help guide,patient care decisions, RARITAN, N.J., Feb. ... Food and Drug Administration (FDA) has granted an ... as an aid in the,monitoring of metastatic prostate ...
... Princeton University has devised a new experimental technique that produces ... human brainstem, the most primitive area of the brain. , ... inquiries into a region that acts as the staging area ... parts of the brain are at the root of many ...
... complications, study finds , , WEDNESDAY, Feb. 27 (HealthDay News) -- ... they should to try to lose weight triple their risk ... doses, a new study finds. , "This is a very ... lead author of a study in the March issue of ...
... will leave nation vulnerable to disease, bioterror and health, threats according ... ... Public Health, WASHINGTON, Feb. 27 While natural disasters,the ... health resources, the U.S. is facing a major public health,workforce crisis that ...
... Combat Vets, PHILADELPHIA, Feb. 27 Secretary of ... by the Department of,Veterans Affairs (VA) of its Vet ... combat veterans, is well,ahead of schedule., In February ... during the,next two years. Fifteen of those centers are ...
... Substantiates Marketability of Propess(R) --, PLYMOUTH MEETING, ... BJGP ) (,BMP Sunstone, or the ,Company,), ... Group at the,Obstetrics and Gynecology Branch of the ... labor induction in late-stage pregnancy., The Guidelines ...
Cached Medicine News:Health News:FDA Clears Cellsearch(TM) Circulating Tumor Cell Test for Monitoring Metastatic Prostate Cancer Patients 2Health News:FDA Clears Cellsearch(TM) Circulating Tumor Cell Test for Monitoring Metastatic Prostate Cancer Patients 3Health News:FDA Clears Cellsearch(TM) Circulating Tumor Cell Test for Monitoring Metastatic Prostate Cancer Patients 4Health News:First look: Princeton researchers peek into deepest recesses of human brain 2Health News:First look: Princeton researchers peek into deepest recesses of human brain 3Health News:'Diabulimia' Triples Risk of Death Among Women With Diabetes 2Health News:More Than 250,000 Additional Public Health Workers Needed by 2020 to Avert Public Health Crisis 2Health News:More Than 250,000 Additional Public Health Workers Needed by 2020 to Avert Public Health Crisis 3Health News:VA Has Added 20 New Vet Centers 2Health News:BMP Sunstone's Propess(R) Recommended as First Line Treatment By the Chinese Medical Association 2Health News:BMP Sunstone's Propess(R) Recommended as First Line Treatment By the Chinese Medical Association 3
(Date:8/27/2014)... -- "Fatty Liver Disease Global Clinical Trials Review, H2, ... trial scenario. This report provides elemental information and data ... Disease . It includes an overview of the trial ... of trial conduction across the globe. The databook offers ... phase, trial status, prominence of the sponsors and also ...
(Date:8/27/2014)... WARSAW, Ind. , Aug. 27, 2014  Zimmer ... in musculoskeletal care, announced that it will be participating ... the Grand Hyatt in New York, New ... David Dvorak , President and CEO of Zimmer, will ... Binder , President and CEO of Biomet, will join ...
(Date:8/27/2014)... , NEW YORK and LONDON ... provider of market research solutions, MarketResearch.com is pleased ... its Kalorama Information Medical Devices Knowledge Center. ... easy-to-use platform hosting the latest market research in ... entire library of reports from industry expert, Kalorama ...
Breaking Medicine Technology:Fatty Liver Disease Therapeutics Clinical Trials Market Review 2014 Analysis Report Available at MarketOptimizer.org 2Fatty Liver Disease Therapeutics Clinical Trials Market Review 2014 Analysis Report Available at MarketOptimizer.org 3Fatty Liver Disease Therapeutics Clinical Trials Market Review 2014 Analysis Report Available at MarketOptimizer.org 4Fatty Liver Disease Therapeutics Clinical Trials Market Review 2014 Analysis Report Available at MarketOptimizer.org 5MarketResearch.com: New Medical Devices Research Reports Added to Kalorama Information Knowledge Center 2MarketResearch.com: New Medical Devices Research Reports Added to Kalorama Information Knowledge Center 3
... SEATTLE, May 2, 2011 CMC Biologics, a ... Copenhagen, Denmark and Seattle, Washington USA, announced today ... at its Chief Executive Officer. CMC Biologics, a ... world class, fully integrated, biopharmaceutical process development and ...
... SAN DIEGO, May 2, 2011 Volcano Corporation (NASDAQ: ... of precision intravascular diagnosis and therapy guidance tools designed ... disease, said today that it will be participating in ... May 10. The presentation by John Dahldorf, ...
Cached Medicine Technology:CMC Biologics Announces Appointment of New CEO 2
... The new line of Myoquick systemplus Multi-channels Evoked ... of Micromed in the neurophysiology field and shows ... Multi-channel EP unit adopt the 32 channels headbox ... of the ISA 100x EP family headboxes: ISA ...
Solid steel construction for lifelong quality. Strong, smooth and quiet electro-mechanical up/down movement. Dual castor, locking wheels for use on carpet or tile flooring. Easy cleaning, deluxe lami...
If you presently have an exam chair that is separate from the instrument stand, we can solve your access problem with a Burton 1200 Chair-exchanger...
... A marvel of engineering and innovative ... precision, unparalleled quality and masterful workmanship. At ... bring the ophthalmic industry a truly innovative ... From product design to quality construction and ...
Medicine Products: