Navigation Links
Gene-Based Screen Spots Cervical Cancer Earlier

It could lengthen the time needed between tests, researchers say

THURSDAY, Oct. 4 (HealthDay News) -- Compared to conventional tests, human papillomavirus (HPV) DNA testing enables earlier detection of lesions that lead to cervical cancer, Dutch researchers say.

That means women could go longer between screenings, say researchers at the VU University Medical Center in Amsterdam.

The study included more than 17,000 women ages 29 to 56. Of those, close to 8,600 were assigned to receive HPV DNA testing to detect the high-risk types of HPV that can cause cervical cancer. The other half underwent conventional cytological testing. Five years later, both groups of women received both cytological and HPV DNA testing.

At the start of the study, more CIN3+ lesions (cervical cancer and its most serious precursor lesions) were detected in women who had HPV DNA testing (68 of 8,575) than in those who had conventional cytological testing (40 of 8,580). Five years later, fewer CIN3+ lesions were detected in the women who'd had HPV DNA testing (24 of 8,413) than in those who'd had conventional cytological testing (56 of 8,456).

While the number of lesions detected over the two rounds of testing didn't differ between the groups, the lesions were detected earlier in the HPV DNA testing group, the researchers said.

"Our results show that implementation of HPV DNA testing in cervical screening leads to earlier detection of clinically relevant cervical lesions. On the basis of this data, we suggest that the current screening interval of five years could be extended by at least one year. The extension will be advantageous to women because of a reduction in the lifetime number of screening tests and referrals," the study authors wrote.

"A full cost-effectiveness analysis will help to determine whether primary HPV testing alone is the preferred strategy for primary cervical screening," they concluded.

The study was published in The Lancet medical journal.

More information

The U.S. National Women's Health Information Center has more about cervical cancer.

-- Robert Preidt

SOURCE: The Lancet, news release, Oct. 3, 2007

Copyright©2007 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Folic Acid blows Gene-based Colon Cancer
2. A sunscreen from the sea
3. Need for Colon cancer screening
4. The Use Of MRI For Screening Of Breast Cancer Questioned
5. Adopting Easier Methods To Screen Insulin Resistance
6. Early Screening For Cancer May Save Lives
7. Mobile Endoscopic Facilities For Health Screening
8. DNA biochip for genetic screening
9. Breast screening among diabetic women
10. Screening device for ovarian cancer
11. Fast screening for macular degeneration
Post Your Comments:
(Date:12/1/2015)... , ... December 01, 2015 , ... With FCPX ... and with full control over customization, the possibilities are truly endless, all with a ... randomization, overlay depth position, vertical flip, horizontal flip, depth of field and more, all ...
(Date:12/1/2015)... ... 01, 2015 , ... SonaCare Medical congratulates the University College ... Award on November 18th. This prestigious award recognizes annually organizations that cultivate truly ... the medical landscape. , The UCLH team won the award for their innovative ...
(Date:11/30/2015)... ... November 30, 2015 , ... ... Brooke Bennett are collaborating with brands across various categories through traditional and social ... make up an elite group of Gold Medal Moms who can connect with ...
(Date:11/30/2015)... ... 01, 2015 , ... The National Association of Professional ... its VIP Woman of the Year Circle. She is recognized with this prestigious ... for professional women, boasting 850,000 members and over 200 operating Local Chapters. , ...
(Date:11/30/2015)... Los Angeles, California (PRWEB) , ... November 30, ... ... in all the programs of the19th Bi-National Convention of the Federation of Philippine ... Resort and Casino in Las Vegas, Nevada. , 1Heart Caregiver Services, as ...
Breaking Medicine News(10 mins):
(Date:12/1/2015)... , December 1, 2015 ... Injectables, Topical Contraceptives, Male Condoms, Female Condoms, ... Rings, Contraceptive Diaphragms, Contraceptive Sponges, Non-Surgical Permanent ... Share, Growth, Trends and Forecast 2014 - ... Market Research (TMR).The report states that the ...
(Date:12/1/2015)...   MabVax Therapeutics Holdings, Inc . (OTCQB: MBVX), ... filed an Investigational New Drug Application (IND) with the ... lead fully human antibody product HuMab 5B1 as a ... initiate the Phase I clinical trial early in 2016. ... The planned Phase I trial will evaluate the safety, ...
(Date:12/1/2015)... , Dec. 1, 2015  InCarda Therapeutics, Inc. (InCarda), ... commercialization of therapies for cardiovascular conditions via the inhalation ... business in Australia . InCarda is ... Australia in the first half ... and medical centers in Adelaide ...
Breaking Medicine Technology: