Navigation Links
Gene Activity May Explain Deadlier Breast Cancers Among Younger Women
Date:7/9/2008

Study finds more than 350 common sets of genes in patients under 45

WEDNESDAY, July 9 (HealthDay News) -- Genetic activity in breast cancer cells from younger patients could explain why tumors tend to more aggressive when they strike at a younger age.

"We haven't had a good reason why younger women do worse than older women," said senior study author Dr. Kimberly Blackwell, director of the clinical trials program in breast cancer at Duke University. "This study offers some insight into why younger women do worse."

"This is a real testament that we're beginning to define, from a molecular basis, why certain patients do so poorly," said Dr. Jay Brooks, chairman of hematology/oncology at Ochsner Health System in Baton Rouge, La. "I think this will go a long way to helping define a population that, hopefully, would have more aggressive treatments."

The results are in the July 10 issue of the Journal of Clinical Oncology.

Breast cancer tends to be more aggressive in younger women, responds less well to existing treatments such as radiation, surgery and chemotherapy, and has higher recurrence and lower survival rates.

"You think of breast cancer as sort of like a mosaic pattern with certain patterns that are very bad and certain patterns that are very good," said Dr. Otis Brawley, chief medical officer of the American Cancer Society. "You're talking about 600 different genes in the mosaic patterns, and you end up with certain cancers that are very aggressive and some cancers that are not so aggressive. We tend to see more aggressive cancers in younger women versus older women."

"We've known for 60 or 70 years that cancers tended to be more aggressive in younger women," Brawley said. "Now we're actually looking at the genetics."

For this study, Duke researchers analyzed samples of almost 800 early-stage breast tumors in two groups of women: those aged 45 and under and those a
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Seizures in newborns can be detected with small, portable brain activity monitors
2. UK and US guidelines on kids physical activity levels need rethinking
3. Activity-Linked Heat Illness Needs Prompt Attention
4. Scientists find how neural activity spurs blood flow in the brain
5. Experimental Drug Fights Multiple Sclerosis Activity
6. Lifestyle can alter gene activity, lead to insulin resistance
7. Brain Activity May Predict Schizophrenia Behavior
8. In quakes aftermath, Chinese sift through rubble for radioactivity
9. Disturbed rest, activity linked to mortality in older men
10. Teen Sexual Activity Increases, Contraceptive Use Decreases
11. Clinical study shows biological and clinical activity in relapsed leukemia patients
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Gene Activity May Explain Deadlier Breast Cancers Among Younger Women
(Date:4/17/2014)... scientists and their partners have found that their proprietary ... transmission of multiple sexually transmitted infections (STIs) in both ... virus 2 (HSV-2), and human papillomavirus (HPV). The USAID-funded ... is effective against multiple strains of HIV, and has ... three viruses of at least eight hours prior to ...
(Date:4/17/2014)... therapy improves general blood flow and alleviates muscle ... researchers at the University of Illinois at Chicago. ... print in the Archives of Physical Medicine ... vascular function in people who had not exercised, ... of their level of physical activity. , Improved ...
(Date:4/17/2014)... of Canadians surveyed said they would participate in public ... of genetic conditions, only 80 per cent said they ... sequence their newborns, genomes.,Most newborns in North America have ... two of life in which a tiny amount of ... about five to 54 conditions, depending on the state ...
(Date:4/17/2014)... as the leading weapon against the deadly disease could ... research indicating it simply needs to be administered differently. ... cheap anti-malarial drug chloroquine in treating and preventing the ... half a million people each year around the world. ... to chloroquine, but research carried out at the Australian ...
(Date:4/16/2014)... Ariz. April 15, 2014 The Translational Genomics ... at their annual Founders Dinner for their support of ... event took place March 28 in Scottsdale. , Catherine ... Ivy Foundation, received TGen,s John S. McCain Leadership Award, ...
Breaking Medicine News(10 mins):Health News:Animal study provides first evidence that gel can prevent multiple virus transmission in vagina/rectum 2Health News:Massage therapy improves circulation, eases muscle soreness 2Health News:Researcher looks at public perceptions around newborn testing 2Health News:Researcher looks at public perceptions around newborn testing 3Health News:Scientists find new way to fight malaria drug resistance 2Health News:TGen honors Catherine Ivy and Craig Jackson with Leadership; Collaborative Spirit awards 2
... of interoperable Health Information Technology (HIT) will be ... the U.S. healthcare system," Yul D. Ejnes, MD, FACP, ... Health today. "Unfortunately, without adequate financial incentives, small ... technological curve." Dr. Ejnes, a member of the Board ...
... launches first of three-part series, MONTCLAIR, N.J., July ... the launch of an educational Webcast series on,chronic pain ... chronic pain sufferer, Nikki Stone. The first in the,three-part ... You Back" is available today at http://www.painawareness.org ., ...
... July 24 Colombia has appointed Dallas sports,chiropractor, Dr. ... medical team,during the upcoming Olympic Games in Beijing. Dr. ... worked with the Costa,Rican team for the 2007 Pan ... a privilege to bring the profession to an international ...
... BURLINGTON, Mass., July 24 Palomar Medical,Technologies, Inc. (Nasdaq: ... devices for hair removal and other cosmetic treatments, will,hold ... financial,results on Thursday, July 31, 2008 at 11:30AM Eastern ... 362-4831 at 11:20 AM Eastern Time on,that day. The ...
... The University of Queensland is helping to increase medical ... advanced clinical training facility. , UQ,s Rural Clinical ... and Learning Centre to its portfolio, with space to ... adjacent to the Toowoomba Base Hospital in West Street, ...
... new research facility is planned to enable unprecedented understanding ... shape human behaviour. The 28.5 million funding comes ... Universities and Skills (DIUS), and will be used for ... be a collaboration between the Economic and Social Research ...
Cached Medicine News:Health News:ACP says Medicare should increase payments for physicians that use HIT to improve quality 2Health News:Video: Olympic Games Gold Medalist Nikki Stone Joins Chronic Pain Experts in Educational Webcasts 2Health News:Video: Olympic Games Gold Medalist Nikki Stone Joins Chronic Pain Experts in Educational Webcasts 3Health News:Video: Olympic Games Gold Medalist Nikki Stone Joins Chronic Pain Experts in Educational Webcasts 4Health News:Video: Olympic Games Gold Medalist Nikki Stone Joins Chronic Pain Experts in Educational Webcasts 5Health News:Video: Olympic Games Gold Medalist Nikki Stone Joins Chronic Pain Experts in Educational Webcasts 6Health News:Video: Olympic Games Gold Medalist Nikki Stone Joins Chronic Pain Experts in Educational Webcasts 7Health News:Colombia Appoints Dallas Chiropractor to Olympic Team 2Health News:Palomar Medical Technologies to Host Second Quarter 2008 Financial Results Conference Call and Webcast on July 31, 2008 2Health News:New $4.2m UQ medical center to boost rural doctor numbers 2Health News:£28.5M investment for groundbreaking new research facility 2
(Date:1/15/2014)... 2014  Manufacturers, suppliers and distributors of innovative medical-related ... their most important business assets, intellectual property (IP). ... Because of the highly-competitive nature of the ... the most litigious industry sectors of cases involving ...
(Date:1/15/2014)... , Jan. 15, 2014 The Cadence Fitness ... Fitness Center by the Medical Fitness Association, a non-profit ... achieve their full potential. The Cadence Fitness & Health ... western suburbs and second in the Chicagoland area. ...
(Date:1/15/2014)... 2014 Reportlinker.com announces that a new ... catalogue: Global Markets ... -- Focus on End Users ... A drug delivery system is ...
Breaking Medicine Technology:Intellectual Property Insurance for Medical-related Products and Services 2Cadence Fitness & Health Center Certified as Medical Fitness Facility 2Cadence Fitness & Health Center Certified as Medical Fitness Facility 3Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 2Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 3Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 4Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 5Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 6Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 7Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 8Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 9Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 10Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 11Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 12Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 13Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 14Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 15Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 16Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 17Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 18
... organiser UBM Live , a division of UBM ... CPhI Japan events line-up that is set to return ... March, 2012. The Pharmatech Japan event, which focuses on ... veterinary and medical industries, will join the Japan Pharma ...
... Pharmaceuticals, Inc. (Nasdaq: AUXL ) today announced ... Capital Global Healthcare Conference to be held March 13-14, ... Sargent, Vice President, Investor Relations and Corporate Communications, is ... its product pipeline at 8:00 a.m. ET on Tuesday, ...
Cached Medicine Technology:New Pharmatech Event to be Introduced Alongside CPhI and P-MEC Japan 2New Pharmatech Event to be Introduced Alongside CPhI and P-MEC Japan 3Auxilium Pharmaceuticals to Present at the 2012 Barclays Capital Global Healthcare Conference 2Auxilium Pharmaceuticals to Present at the 2012 Barclays Capital Global Healthcare Conference 3Auxilium Pharmaceuticals to Present at the 2012 Barclays Capital Global Healthcare Conference 4
... Acid is a non-irritating rapid exfoliator. Lactic Acid ... to peel and exfoliating agents in skin care ... other exfoliators for a long period and want ... occurring human metabolite, and combined with the chemical ...
... is available in two innovative formulations: Level ... active). The Level I (40% active) formulation ... extract, which DCL scientists have identified and ... and calm the skin while the beneficial ...
... CosmoDerm and CosmoPlast are dermal fillers ... acne scars and other soft tissue contour ... of the lip border. The collagen in ... dermal tissue that is grown under controlled ...
... is a gel of ... species of bacteria, chemically ... suspended in phosphate,buffered saline ... and concentration of 20 ...
Medicine Products: