Navigation Links
Gender Matches Benefit Heart Transplants
Date:11/12/2008

Best results achieved with male-to-male surgeries, study finds

WEDNESDAY, Nov. 12 (HealthDay News) -- Matching the gender of heart donors and recipients helps short- and long-term survival of heart transplant patients.

So say U.S. researchers who analyzed data on 18,240 patients who received a heart transplant between 1998 and 2007.

"Heart size would seem to be the most obvious factor; beyond that, no one knows why sex matching is important to transplant survival," study first author Dr. Eric Weiss, a postdoctoral research fellow in the cardiac surgery division at the Johns Hopkins University Medical Institutions, said in an American Heart Association news release.

"In clinical transplantation, we generally don't assume that organs from male and female donors have inherent differences affecting long-term outcomes, but our data suggest that there are important differences which must be taken into account," Weiss said.

Of the heart transplant patients included in the study, 71 percent were matched by gender to their donor (77 percent of male recipients and 51 percent of female recipients). Twenty-five percent of the patients died after their transplant.

The data analysis showed that matching donor and recipient by gender resulted in:

  • 13 percent lower risk of graft rejection within the first year.
  • 14 percent lower rate of graft rejection over the study period.
  • 25 percent lower 30-day death rate.
  • 20 percent lower one-year death rate.

Female recipients who received a heart from a male donor had the greatest risk of death, about 20 percent higher than when a male donor was matched with a male recipient. Male-to-male matching was most successful, with a 61 percent cumulative chance for survival, the study found.

The findings were expected to be presented Nov. 12 at the American Heart Association's annual scientific sessions, in New Orleans.

Despite the findings, the researchers don't recommend that patients wait longer for a same-sex heart.

"Clearly, receiving a heart transplant from a donor of opposite sex is preferable to severe heart failure. If equivalent donors exist for a given patient, our data suggest that picking a sex matched donor may lead to improved short- and long-term survival," Weiss said.

More information

The U.S. National Heart, Lung, and Blood Institute has more about heart transplantation.



-- Robert Preidt



SOURCE: American Heart Association, news release, Nov. 12, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Gender affects perceptions of infidelity
2. Gender is a relative term in politics, MU study finds
3. UNC receives record $181 million grant to evaluate health, poverty and gender programs worldwide
4. APA resolves to play leading role in improving treatment for gender-variant people
5. Alcohols Impact on Heart, Stroke Risk Differs by Gender
6. Gender Plays Role in Post-Concussion Healing
7. Gender, time of day affect response to vaccination
8. Gender Plays Role in Kidney Transplant Outcomes
9. Gender differences and heart disease
10. Gender affects reaction to HIV-prevention materials
11. Risk Factors for Eating Disorders Vary by Gender
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/23/2017)... ... June 23, 2017 , ... ... and two new videos highlight the importance of correctly using a meat thermometer. ... who has done extensive research on consumer food safety habits. Dr. Bruhn explains ...
(Date:6/23/2017)... ... June 23, 2017 , ... 21 Middle East and South Asia ... 21 leaders from government, business and civil society in 11 countries across the Middle ... fall, engaging in a transformative exchange of knowledge and ideas with the leading minds ...
(Date:6/23/2017)... ... 2017 , ... PureLife Dental is pleased to announce that California Dental Association ... part of the amalgam separator endorsement, all CDA members may purchase an ECO II ... retail value. This partnership between PureLife and CDA is especially timely as it coincides ...
(Date:6/23/2017)... ... ... American Farmer, will feature Chr. Hansen, Inc (CHR Hansen) in an upcoming episode ... Farmer airs Tuesdays at 8:30aET on RFD-TV. Check your local listings for more info. ... 1874 after a groundbreaking discovery of how to industrialize enzymes. Rooted in science and ...
(Date:6/23/2017)... ... June 23, 2017 , ... ... and related services to families and business owners in and around Lackawanna County, ... benefit senior citizens in the area. , Meals on Wheels of NEPA provides ...
Breaking Medicine News(10 mins):
(Date:6/5/2017)... The Cincinnati location of ... (NYSE: DPLO), has been awarded a Top Workplaces 2017 ... Results are based on an employee survey administered by WorkplaceDynamics, ... improvement. The survey measures several aspects of workplace culture, including ... ...
(Date:6/3/2017)... June 3, 2017  Eli Lilly and Company ... results from the Phase 3 MONARCH 2 study ... 6 inhibitor, in combination with fulvestrant, significantly improved ... alone in women with hormone-receptor-positive (HR+), human epidermal ... who have relapsed or progressed after endocrine therapy ...
(Date:6/1/2017)... BELL, Pa. , June 1, 2017 ... (PRN) and Veterinarian Recommended Solutions (VRS), and KD Pharma ... investment in Nutriceutical Holdings by KD Pharma Group. KD ... Holdings with the option to acquire the entire company. ... partner in KD. They are committed to growing the ...
Breaking Medicine Technology: