Navigation Links
Gender Matches Benefit Heart Transplants
Date:11/12/2008

Best results achieved with male-to-male surgeries, study finds

WEDNESDAY, Nov. 12 (HealthDay News) -- Matching the gender of heart donors and recipients helps short- and long-term survival of heart transplant patients.

So say U.S. researchers who analyzed data on 18,240 patients who received a heart transplant between 1998 and 2007.

"Heart size would seem to be the most obvious factor; beyond that, no one knows why sex matching is important to transplant survival," study first author Dr. Eric Weiss, a postdoctoral research fellow in the cardiac surgery division at the Johns Hopkins University Medical Institutions, said in an American Heart Association news release.

"In clinical transplantation, we generally don't assume that organs from male and female donors have inherent differences affecting long-term outcomes, but our data suggest that there are important differences which must be taken into account," Weiss said.

Of the heart transplant patients included in the study, 71 percent were matched by gender to their donor (77 percent of male recipients and 51 percent of female recipients). Twenty-five percent of the patients died after their transplant.

The data analysis showed that matching donor and recipient by gender resulted in:

  • 13 percent lower risk of graft rejection within the first year.
  • 14 percent lower rate of graft rejection over the study period.
  • 25 percent lower 30-day death rate.
  • 20 percent lower one-year death rate.

Female recipients who received a heart from a male donor had the greatest risk of death, about 20 percent higher than when a male donor was matched with a male recipient. Male-to-male matching was most successful, with a 61 percent cumulative chance for survival, the study found.

The findings were expected to be presented Nov. 12 at the American Heart Association's annual scientific sessions, in New Orleans.

Despite the findings, the researchers don't recommend that patients wait longer for a same-sex heart.

"Clearly, receiving a heart transplant from a donor of opposite sex is preferable to severe heart failure. If equivalent donors exist for a given patient, our data suggest that picking a sex matched donor may lead to improved short- and long-term survival," Weiss said.

More information

The U.S. National Heart, Lung, and Blood Institute has more about heart transplantation.



-- Robert Preidt



SOURCE: American Heart Association, news release, Nov. 12, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Gender affects perceptions of infidelity
2. Gender is a relative term in politics, MU study finds
3. UNC receives record $181 million grant to evaluate health, poverty and gender programs worldwide
4. APA resolves to play leading role in improving treatment for gender-variant people
5. Alcohols Impact on Heart, Stroke Risk Differs by Gender
6. Gender Plays Role in Post-Concussion Healing
7. Gender, time of day affect response to vaccination
8. Gender Plays Role in Kidney Transplant Outcomes
9. Gender differences and heart disease
10. Gender affects reaction to HIV-prevention materials
11. Risk Factors for Eating Disorders Vary by Gender
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/21/2017)... ... 2017 , ... Florida Pain Relief Group, a division of Physician Partners of ... Silver Palm Ave., Melbourne, on Monday, May 22. Initially the clinic will be supervised ... practice, PPOA operates 23 pain management clinics in Florida and the Dallas-Fort Worth, Texas ...
(Date:5/21/2017)... ... ... Following the tragic and widely publicized death of Rory Staunton, 12, from ... follow a protocol to quickly identify and treat the condition. , The mandate ... have saved Rory or anyone else’s life. , Now, five years after the ...
(Date:5/19/2017)... ... May 19, 2017 , ... In a continuous effort to raise awareness ... online mattress company that specializes in natural and organic latex mattresses, has announced that ... for every unique share their recent viral Facebook video receives, up to ...
(Date:5/19/2017)... ... May 19, 2017 , ... ... in an upcoming episode of Innovations with Ed Begley, Jr., airing fourth quarter ... the distributor of a clean, organic dietary supplement made from naturally occurring ingredients. ...
(Date:5/19/2017)... ... ... Springfield, Vermont-based law firm of Brady/Callahan has released a new Personal Injury ... Experienced Personal Injury Attorney, " the article offers insight for people who have questions, ... if someone is injured due to another person's negligence, they may want ...
Breaking Medicine News(10 mins):
(Date:5/18/2017)... 17, 2017  Bayer announced today that the latest ... presented at the 53 rd Annual Meeting of ... June 2-6 in Chicago . ... prostate, colorectal, liver and thyroid cancers, as well as ... II CHRONOS-1 trial of copanlisib in patients with relapsed ...
(Date:5/10/2017)... -- Hologic, Inc. (Nasdaq: HOLX ) announced ... quarter ended April 1, 2017 .   GAAP diluted ... to the prior year period as the sale of ... while non-GAAP diluted EPS of $0.50 increased 6.4%.  Revenue ... currency terms.  Excluding the effects of blood screening and ...
(Date:5/9/2017)... Zimmer Biomet Holdings, Inc. (NYSE and SIX: ... it has earned a spot on Forbes, ... was ranked among 500 U.S. employers as well as ... and Services. The annual Forbes ... survey of over 30,000 employees across 25 industries. The ...
Breaking Medicine Technology: