Navigation Links
Gender Matches Benefit Heart Transplants
Date:11/12/2008

Best results achieved with male-to-male surgeries, study finds

WEDNESDAY, Nov. 12 (HealthDay News) -- Matching the gender of heart donors and recipients helps short- and long-term survival of heart transplant patients.

So say U.S. researchers who analyzed data on 18,240 patients who received a heart transplant between 1998 and 2007.

"Heart size would seem to be the most obvious factor; beyond that, no one knows why sex matching is important to transplant survival," study first author Dr. Eric Weiss, a postdoctoral research fellow in the cardiac surgery division at the Johns Hopkins University Medical Institutions, said in an American Heart Association news release.

"In clinical transplantation, we generally don't assume that organs from male and female donors have inherent differences affecting long-term outcomes, but our data suggest that there are important differences which must be taken into account," Weiss said.

Of the heart transplant patients included in the study, 71 percent were matched by gender to their donor (77 percent of male recipients and 51 percent of female recipients). Twenty-five percent of the patients died after their transplant.

The data analysis showed that matching donor and recipient by gender resulted in:

  • 13 percent lower risk of graft rejection within the first year.
  • 14 percent lower rate of graft rejection over the study period.
  • 25 percent lower 30-day death rate.
  • 20 percent lower one-year death rate.

Female recipients who received a heart from a male donor had the greatest risk of death, about 20 percent higher than when a male donor was matched with a male recipient. Male-to-male matching was most successful, with a 61 percent cumulative chance for survival, the study found.

The findings were expected to be presented Nov. 12 at the American Heart Association's annual scientific sessions, in New Orleans.

Despite the findings, the researchers don't recommend that patients wait longer for a same-sex heart.

"Clearly, receiving a heart transplant from a donor of opposite sex is preferable to severe heart failure. If equivalent donors exist for a given patient, our data suggest that picking a sex matched donor may lead to improved short- and long-term survival," Weiss said.

More information

The U.S. National Heart, Lung, and Blood Institute has more about heart transplantation.



-- Robert Preidt



SOURCE: American Heart Association, news release, Nov. 12, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Gender affects perceptions of infidelity
2. Gender is a relative term in politics, MU study finds
3. UNC receives record $181 million grant to evaluate health, poverty and gender programs worldwide
4. APA resolves to play leading role in improving treatment for gender-variant people
5. Alcohols Impact on Heart, Stroke Risk Differs by Gender
6. Gender Plays Role in Post-Concussion Healing
7. Gender, time of day affect response to vaccination
8. Gender Plays Role in Kidney Transplant Outcomes
9. Gender differences and heart disease
10. Gender affects reaction to HIV-prevention materials
11. Risk Factors for Eating Disorders Vary by Gender
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/17/2017)... , ... August 17, 2017 , ... Inc. Magazine Unveils ... at No. 132 with Three-Year Sales Growth of 3,004.8% , NEW YORK, August 16, ... Inc. 5000, the most prestigious ranking of the nation's fastest-growing private companies. The list ...
(Date:8/17/2017)... , ... August 17, 2017 , ... ... Employers , an international competition, were announced today. The awards recognize the world’s ... suppliers who help to create and drive great places to work. , A ...
(Date:8/16/2017)... ... August 16, 2017 , ... Blue Health Intelligence (BHI) ... President, Chief Medical Officer. Dr. Spiro brings over 30 years of clinical, healthcare IT, ... for BHI’s cutting-edge analytics solutions. , “I am thrilled to welcome Dr. Spiro ...
(Date:8/16/2017)... Atlanta, GA (PRWEB) , ... August 16, 2017 , ... ... the new Inc. 5000. The company ranked #4429 on the newly released, 36th annual ... The list represents a unique look at the most successful companies within the American ...
(Date:8/16/2017)... ... August 16, 2017 , ... ... their recently launched community enrichment program. Partnering once again with Boys & Girls ... competition to help find the area’s very own American Idol. With all proceeds ...
Breaking Medicine News(10 mins):
(Date:8/2/2017)... AROMAS, Calif. , Aug. 2, 2017 /PRNewswire/ ... by Continental Who,s Who as a Pinnacle Lifetime ... currently the Key Account Manager at Turing Pharmaceuticals, ... communications, negotiations, troubleshooting and relationship building.                ... has more than 25 years of experience ...
(Date:7/31/2017)... FLINT, Mich. , July 31, 2017  Diplomat Pharmacy, ... companies in southeast Michigan by ... feature ranks private and public companies by three-year revenue growth. ... To view the complete list, ... Crain,s Fast 50 is an incredible triumph," said Phil ...
(Date:7/27/2017)... -- Zimmer Biomet Holdings, Inc. (NYSE and SIX: ZBH) today reported ... The Company reported second quarter net sales of $1.954 ... period, and an increase of 2.1% on a constant ... from the LDR Holding Corporation acquisition, second quarter 2017 ... or 0.3% on a constant currency basis. ...
Breaking Medicine Technology: