Navigation Links
Gender Matches Benefit Heart Transplants
Date:11/12/2008

Best results achieved with male-to-male surgeries, study finds

WEDNESDAY, Nov. 12 (HealthDay News) -- Matching the gender of heart donors and recipients helps short- and long-term survival of heart transplant patients.

So say U.S. researchers who analyzed data on 18,240 patients who received a heart transplant between 1998 and 2007.

"Heart size would seem to be the most obvious factor; beyond that, no one knows why sex matching is important to transplant survival," study first author Dr. Eric Weiss, a postdoctoral research fellow in the cardiac surgery division at the Johns Hopkins University Medical Institutions, said in an American Heart Association news release.

"In clinical transplantation, we generally don't assume that organs from male and female donors have inherent differences affecting long-term outcomes, but our data suggest that there are important differences which must be taken into account," Weiss said.

Of the heart transplant patients included in the study, 71 percent were matched by gender to their donor (77 percent of male recipients and 51 percent of female recipients). Twenty-five percent of the patients died after their transplant.

The data analysis showed that matching donor and recipient by gender resulted in:

  • 13 percent lower risk of graft rejection within the first year.
  • 14 percent lower rate of graft rejection over the study period.
  • 25 percent lower 30-day death rate.
  • 20 percent lower one-year death rate.

Female recipients who received a heart from a male donor had the greatest risk of death, about 20 percent higher than when a male donor was matched with a male recipient. Male-to-male matching was most successful, with a 61 percent cumulative chance for survival, the study found.

The findings were expected to be presented Nov. 12 at the American Heart Association's annual scientific sessions, in New Orleans.

Despite the findings, the researchers don't recommend that patients wait longer for a same-sex heart.

"Clearly, receiving a heart transplant from a donor of opposite sex is preferable to severe heart failure. If equivalent donors exist for a given patient, our data suggest that picking a sex matched donor may lead to improved short- and long-term survival," Weiss said.

More information

The U.S. National Heart, Lung, and Blood Institute has more about heart transplantation.



-- Robert Preidt



SOURCE: American Heart Association, news release, Nov. 12, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Gender affects perceptions of infidelity
2. Gender is a relative term in politics, MU study finds
3. UNC receives record $181 million grant to evaluate health, poverty and gender programs worldwide
4. APA resolves to play leading role in improving treatment for gender-variant people
5. Alcohols Impact on Heart, Stroke Risk Differs by Gender
6. Gender Plays Role in Post-Concussion Healing
7. Gender, time of day affect response to vaccination
8. Gender Plays Role in Kidney Transplant Outcomes
9. Gender differences and heart disease
10. Gender affects reaction to HIV-prevention materials
11. Risk Factors for Eating Disorders Vary by Gender
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... Birmingham, Lake Orion, Clarkston, Michigan (PRWEB) , ... ... ... their direction with respect to fertility once they have been diagnosed with endometriosis. ... for tolerable intercourse but they also require a comprehensive approach that can help ...
(Date:6/25/2016)... Aliso Viejo, California (PRWEB) , ... June 25, 2016 , ... ... preset to fit their specific project," said Christina Austin - CEO of Pixel Film ... all fully customizable and all within Final Cut Pro X . Simply select ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... On Friday, ... presented a Bronze Wellness at Work award to iHire in recognition of their exemplary ... part of the 7th annual Maryland Workplace Health & Wellness Symposium at the BWI ...
(Date:6/24/2016)... ... ... June 19, 2016 is World Sickle Cell Observance Day. In an effort to ... treatments, Serenity Recovery Center of Marne, Michigan, has issued a pain management ... (SCD) is a disorder of the red blood cells, which can cause episodes of ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive experience with all areas ... , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... June 23, 2016 Capricor ... ), a biotechnology company focused on the discovery, ... that patient enrollment in its ongoing randomized HOPE-Duchenne ... exceeded 50% of its 24-patient target. Capricor expects ... third quarter of 2016, and to report top ...
(Date:6/23/2016)... 2016  Astellas today announced the establishment of Astellas Farma Colombia (AFC), a new affiliate with operations headquartered in ... America . ... ... ... ...
(Date:6/23/2016)... FRANKLIN, Tenn. , June 23, 2016 ... for automating, integrating and transforming the patient ... launch of several innovative new products and ... depth of its revenue cycle offerings. These ... establish more efficient workflows, remain compliant in ...
Breaking Medicine Technology: