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GenVault's GenSolve(TM) Reagents Enable State-of-the-Art Genomic Analysis of Dried Blood Spots
Date:8/5/2009

CARLSBAD, Calif., Aug. 5 /PRNewswire/ -- GenVault Corporation is pleased to report that their DNA recovery product, GenSolve(TM), is enabling independent groups, from diverse research areas, to recover DNA from Guthrie cards and FTA paper for microarray based genomic analysis and Illumina iSelect based genotyping.

Two publications, BMC Research Notes 2009, 2:107 (16 June 2009) and BMC Genetics 2009, 10:38 (22 July 2009) www.biomedcentral.com, illustrate that GenSolve(TM) methodology is capable of recovering DNA of sufficiently high quality for use in genome-wide microarray analysis and SNP genotyping studies. Previously reported methods for recovery of DNA from blood dried on Guthrie cards and FTA paper generated fragments of single stranded, denatured DNA which were unsuitable for such analyses.

"What is exciting about the observations made in these publications is that GenSolve(TM) routinely recovers DNA from either archived Guthrie cards, or FTA cards, in a native double stranded form, that consistently fuels modern Genomic analysis. GenSolve(TM) chemistry confers a significant advantage over previously available DNA recovery technologies because it enables researchers to access high quality DNA for analysis on systems such as the Illumina 610 microarray platform," said Dr. Mike Hogan, GenVault's Chief Scientific Officer.

"We analyze the genomes of cattle across the United States to identify genes that cause variation in economically important genes. GenSolve(TM) enables us to reproducibly recover sufficient quantities of DNA, of the correct size and quality, from dry archived FTA cards for analysis of 54,000 single nucleotide polymorphisms on Illumina's BovineSNP50 BeadChip," said Dr. Matthew McClure from the Division of Animal Science at the University of Missouri-Columbia.

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SOURCE GenVault Corporation
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