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GenOdyssee Receives Notice of Allowance from U.S. Patent Office for Improved Interferon-Alpha Aimed at Hepatitis C
Date:2/14/2008

be uniquely applicable to other important classes of protein therapeutic drugs such as erythropoietin".

Genotype 1 HCV has in recent years become the predominant HCV genotype worldwide. It is estimated that approximately 100 million people are infected with HCV genotype 1 worldwide and that this genotype kills around 200,000 people annually from cirrhosis-related hepatocarcinoma. Genotype 1 patients have not shown improved responses to other IFN-alpha2 variants currently in clinical testing, nor have these patients responded to higher doses of standard-of-care long-lasting IFN-alpha2 drugs. Therefore, says Dr. Escary, "GenOdyssee's improved interferon-alpha variant drug for HCV genotype 1, GEA007.1, which presents no increase in toxicity at therapeutic doses used in HCV treatments, can constitute the next standard of care. GenOdyssee is developing both standard and pegylated versions of GEA007.1 and we believe this will provide a key element in meeting the proven and growing demand for better hepatitis C therapies" added Escary.

About GenOdyssee S.A.

GenOdyssee applies its proprietary population-genetics-based drug discovery approach using a DNA databank representative of more than 90% of the different ethnicities that constitute the current human population, which is screened for natural genetic variants of therapeutic proteins with superior properties. The company pioneered the vision that natural evolution has led to the generation in the current population of unpredictable mutations that confer superior or novel therapeutic status to known important human therapeutic proteins.

GenOdyssee's technology is protected by the international patent application PCT/EP03/13965 and is the sole property of the company. An international examination report delivered by the European Patent Office stated an absence of prior art to such technology in the entire biopharmaceutical industry.

This technology has allowed GenOdyssee to identify a var
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SOURCE GenOdyssee SA
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