Navigation Links
Gel Enables Severed Spinal Cord Fibers to Regrow
Date:4/10/2008

Works in mice, but human clinical trials could start in several years, study says

THURSDAY, April 10 (HealthDay News) -- A nano-engineered gel that inhibits the formation of scar tissue at the site of a spinal injury and enables severed spinal cord fibers to regenerate has been developed by researchers at Northwestern University in Chicago.

They noted that nerve fibers do have the ability to regrow after a spinal injury, but they're blocked by scar tissue that develops around the injury.

After the gel is injected as a liquid into the spinal cord, it self-assembles into a scaffold that supports new nerve fibers as they grow up and down the spinal cord and penetrate the site of the injury.

Six weeks after the gel was injected into mice with a spinal cord injury, the mice showed great improvement in the ability to use their hind legs and walk. The research was published in the April 2 issue of The Journal of Neuroscience.

"We are very excited about this. We can inject this without damaging the tissue. It has great potential for treating human beings," lead author Dr. John Kessler, a professor of stem cell biology at Northwestern's Feinberg School of Medicine, said in a prepared statement.

However, he added that it's "important to understand that something that works in mice will not necessarily work in human beings. At this point in time, we have no information about whether this will work in human beings."

"There is no magic bullet or one single thing that solves spinal cord injury, but this gives us a brand new technology to be able to think about treating this disorder. It could be used in combination with other technologies including stem cells, drugs or other kinds of interventions," Kessler said.

He and his colleagues are working on developing the nano-engineered gel to be approved as a pharmaceutical by the U.S. Food and Drug Administration. If they make good progress, a human clinical trial of the gel could begin in several years.

More information

The U.S. National Institute of Neurological Disorders and Stroke has more about spinal cord injury.



-- Robert Preidt



SOURCE: Northwestern University, news release, April 2, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Stanford researchers unmask proteins in telomerase, a substance that enables cancer
2. New method enables design, production of extremely novel drugs
3. Regence Enables Members to Share Feedback With Each Other When Researching Health Care Provider Options
4. Oosight Imaging System Enables a Breakthrough: The Viable Transfer of Genetic Material for Stem Cell Nuclear Reprogramming in Primates
5. IVF technique enables pregnancy without multiple births, Stanford researchers find
6. Verathon Inc. Introduces GlideScope(R) Ranger Single Use Video Laryngoscope for Emergency Departments, EMS and Military; Enables Fast Intubations and Eliminates Time-Consuming Disinfection
7. Alberta physiologist earns top national honor for spinal cord research
8. Omega-3 Fatty Acids Protect the Spinal Cord, Heart, Brain and Eyes
9. Long-Term Data for 884 Patients Show Vertebroplasty for Osteoporotic Spinal Fractures Provides Dramatic Pain Relief, Greatly Decreases Disability
10. Physical Therapists Offer Low-Cost Solution to High-Cost Expenditures for Spinal Conditions
11. UD researchers discover technique for repairing gene defect that causes spinal muscular atrophy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/27/2017)... ... 2017 , ... Miro is the ultimate smart media center that offers a ... TV shows and much more apps for user exploration. Its innovative acoustic design with ... 1280 x 720 provides crisp images with remarkable clarity and color. The WiFi connection ...
(Date:2/27/2017)... ... 27, 2017 , ... Sunshine Coast Health Centre (SCHC), one ... at https://www.sunshinecoasthealthcentre.ca/ , is proud to announce the addition of a registered ... Centre's commitment to innovation in drug rehab and alcohol treatment strategies beyond a ...
(Date:2/27/2017)... (PRWEB) , ... February 27, 2017 , ... New Jersey ... rates, among all types and genders. And the need for advanced services is growing. ... and its top-rated cancer care program, in collaboration with their non-profit partners in their ...
(Date:2/26/2017)... ... February 26, 2017 , ... This is ... the world’s first to be ISO/IEC 17025:2005 INAB accredited for Der p 1 ... 17025:2005 is the globally recognised standard that sets out requirements for the technical ...
(Date:2/26/2017)... ... 2017 , ... IndustryArchive.Org . is announcing a new way for B2B ... now only pay for B.A.N.T. quality sales leads based on the Sellers decision to ... new reality that B2B buyers are controlling the sales process via the Internet and ...
Breaking Medicine News(10 mins):
(Date:2/27/2017)... 27, 2017   Royal Philips (NYSE: ... leader in health technology, today announced 510(k) clearance ... to market its ElastQ Imaging capability, further expanding ... systems. ElastQ Imaging enables simultaneous imaging of tissue ... for the diagnosis of various liver conditions. With ...
(Date:2/27/2017)... , Feb. 27, 2017  RegeneRx Biopharmaceuticals, Inc. ... drug development company focused on tissue protection, repair ... RGN-137, GtreeBNT Co., Ltd., received a positive response ... clinical trial design for RGN-137 to treat epidermolysis ... gel that incorporates Thymosin beta 4 ("Tß4") as ...
(Date:2/27/2017)... BioPharma Corp. (CTI BioPharma) (NASDAQ and MTA: CTIC) today announced ... President and Chief Executive Officer (CEO) and member of the ... Richard Love , interim President and CEO who will ... Craig has over 20 years of experience in hematology, oncology ... Europe . "On behalf of CTI BioPharma,s ...
Breaking Medicine Technology: