Navigation Links
Gel Enables Severed Spinal Cord Fibers to Regrow
Date:4/10/2008

Works in mice, but human clinical trials could start in several years, study says

THURSDAY, April 10 (HealthDay News) -- A nano-engineered gel that inhibits the formation of scar tissue at the site of a spinal injury and enables severed spinal cord fibers to regenerate has been developed by researchers at Northwestern University in Chicago.

They noted that nerve fibers do have the ability to regrow after a spinal injury, but they're blocked by scar tissue that develops around the injury.

After the gel is injected as a liquid into the spinal cord, it self-assembles into a scaffold that supports new nerve fibers as they grow up and down the spinal cord and penetrate the site of the injury.

Six weeks after the gel was injected into mice with a spinal cord injury, the mice showed great improvement in the ability to use their hind legs and walk. The research was published in the April 2 issue of The Journal of Neuroscience.

"We are very excited about this. We can inject this without damaging the tissue. It has great potential for treating human beings," lead author Dr. John Kessler, a professor of stem cell biology at Northwestern's Feinberg School of Medicine, said in a prepared statement.

However, he added that it's "important to understand that something that works in mice will not necessarily work in human beings. At this point in time, we have no information about whether this will work in human beings."

"There is no magic bullet or one single thing that solves spinal cord injury, but this gives us a brand new technology to be able to think about treating this disorder. It could be used in combination with other technologies including stem cells, drugs or other kinds of interventions," Kessler said.

He and his colleagues are working on developing the nano-engineered gel to be approved as a pharmaceutical by the U.S. Food and Drug Administration. If they make good progress, a human clinical trial of the gel could begin in several years.

More information

The U.S. National Institute of Neurological Disorders and Stroke has more about spinal cord injury.



-- Robert Preidt



SOURCE: Northwestern University, news release, April 2, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Stanford researchers unmask proteins in telomerase, a substance that enables cancer
2. New method enables design, production of extremely novel drugs
3. Regence Enables Members to Share Feedback With Each Other When Researching Health Care Provider Options
4. Oosight Imaging System Enables a Breakthrough: The Viable Transfer of Genetic Material for Stem Cell Nuclear Reprogramming in Primates
5. IVF technique enables pregnancy without multiple births, Stanford researchers find
6. Verathon Inc. Introduces GlideScope(R) Ranger Single Use Video Laryngoscope for Emergency Departments, EMS and Military; Enables Fast Intubations and Eliminates Time-Consuming Disinfection
7. Alberta physiologist earns top national honor for spinal cord research
8. Omega-3 Fatty Acids Protect the Spinal Cord, Heart, Brain and Eyes
9. Long-Term Data for 884 Patients Show Vertebroplasty for Osteoporotic Spinal Fractures Provides Dramatic Pain Relief, Greatly Decreases Disability
10. Physical Therapists Offer Low-Cost Solution to High-Cost Expenditures for Spinal Conditions
11. UD researchers discover technique for repairing gene defect that causes spinal muscular atrophy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... , ... June 25, 2016 , ... Austin residents seeking ... American College of Mohs Surgery and to Dr. Russell Peckham for medical and surgical ... effective treatment for skin cancer. The selective fellowship in Mohs Micrographic Surgery completed by ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... ... athletes and non-athletes recover from injury. Recently, he has implemented orthobiologic procedures as ... City area —Johnson is one of the first doctors to perform the treatment. ...
(Date:6/24/2016)... ... 2016 , ... June 19, 2016 is World Sickle Cell Observance Day. In ... benefits of holistic treatments, Serenity Recovery Center of Marne, Michigan, has issued ... Sickle Cell Disease (SCD) is a disorder of the red blood cells, which can ...
(Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San Diego, CA is excited ... To Recovery® program to drive cancer patients to and from their cancer treatments. ... highest quality of life and ongoing independence. Getting to and from medical treatments ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... client, The Grove Investment Group (TGIG), has initiated cultivation and processing operations at ... Las Vegas and Pahrump, Nevada. , Puradigm is the manufacturer of a complete ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016  American Respiratory Labs (ARL), a ... now able to perform sophisticated lung assessments in patients, homes, thanks ... Inc. Patients are no longer limited to having ... PRO ® , ARL patients like Jeanne R. of ... the comfort of her own home. ...
(Date:6/24/2016)... , June 24, 2016  Arkis BioSciences, a ... invasive and more durable cerebrospinal fluid treatments, today ... The Series-A funding is led by Innova Memphis, ... and other private investors.  Arkis, new financing will ... and the market release of its in-licensed Endexo® ...
(Date:6/23/2016)... -- In a startling report released today, National Safety Council ... comprehensive, proven plan to eliminate prescription opioid overdoses. Prescription ... are tackling the worst drug crisis in recorded U.S. history, assigned ... Kentucky , New Mexico , ... 28 failing states, three – Michigan , ...
Breaking Medicine Technology: