Navigation Links
Gel Enables Severed Spinal Cord Fibers to Regrow
Date:4/10/2008

Works in mice, but human clinical trials could start in several years, study says

THURSDAY, April 10 (HealthDay News) -- A nano-engineered gel that inhibits the formation of scar tissue at the site of a spinal injury and enables severed spinal cord fibers to regenerate has been developed by researchers at Northwestern University in Chicago.

They noted that nerve fibers do have the ability to regrow after a spinal injury, but they're blocked by scar tissue that develops around the injury.

After the gel is injected as a liquid into the spinal cord, it self-assembles into a scaffold that supports new nerve fibers as they grow up and down the spinal cord and penetrate the site of the injury.

Six weeks after the gel was injected into mice with a spinal cord injury, the mice showed great improvement in the ability to use their hind legs and walk. The research was published in the April 2 issue of The Journal of Neuroscience.

"We are very excited about this. We can inject this without damaging the tissue. It has great potential for treating human beings," lead author Dr. John Kessler, a professor of stem cell biology at Northwestern's Feinberg School of Medicine, said in a prepared statement.

However, he added that it's "important to understand that something that works in mice will not necessarily work in human beings. At this point in time, we have no information about whether this will work in human beings."

"There is no magic bullet or one single thing that solves spinal cord injury, but this gives us a brand new technology to be able to think about treating this disorder. It could be used in combination with other technologies including stem cells, drugs or other kinds of interventions," Kessler said.

He and his colleagues are working on developing the nano-engineered gel to be approved as a pharmaceutical by the U.S. Food and Drug Administration. If they make good progress, a human clinical trial of the gel could begin in several years.

More information

The U.S. National Institute of Neurological Disorders and Stroke has more about spinal cord injury.



-- Robert Preidt



SOURCE: Northwestern University, news release, April 2, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Stanford researchers unmask proteins in telomerase, a substance that enables cancer
2. New method enables design, production of extremely novel drugs
3. Regence Enables Members to Share Feedback With Each Other When Researching Health Care Provider Options
4. Oosight Imaging System Enables a Breakthrough: The Viable Transfer of Genetic Material for Stem Cell Nuclear Reprogramming in Primates
5. IVF technique enables pregnancy without multiple births, Stanford researchers find
6. Verathon Inc. Introduces GlideScope(R) Ranger Single Use Video Laryngoscope for Emergency Departments, EMS and Military; Enables Fast Intubations and Eliminates Time-Consuming Disinfection
7. Alberta physiologist earns top national honor for spinal cord research
8. Omega-3 Fatty Acids Protect the Spinal Cord, Heart, Brain and Eyes
9. Long-Term Data for 884 Patients Show Vertebroplasty for Osteoporotic Spinal Fractures Provides Dramatic Pain Relief, Greatly Decreases Disability
10. Physical Therapists Offer Low-Cost Solution to High-Cost Expenditures for Spinal Conditions
11. UD researchers discover technique for repairing gene defect that causes spinal muscular atrophy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... Apple ... care services, staged a mock evacuation of the facility as part of a disaster ... Fire Department, Echo Hose EMS and Shelton City Emergency Manager, as well as the ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Global Healthcare Management’s ... Alexandria Park in Milford, NJ. This free event, sponsored by Global Healthcare Management’s ... The fun run is geared towards children of all ages; it is a ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the ... danger possible to save lost souls in the Philippines. “The Journey: From the Mountains ... a dedicated teacher of the Bible. She has taught all ages and currently teaches ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the largest and ... plans to open a flagship location in Covington, LA at 401 N. U.S. Highway ... store next to Office Depot in the Holiday Square shopping center. Its location allows ...
(Date:10/12/2017)... ... 2017 , ... Asante, a nationally recognized health system in ... existing home health joint venture through an agreement, effective October 1, 2017, to ... home health company with Asante, delivering clinically integrated care, for the past eight ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... -- NDS received FDA 510(k) clearance in May 2017 for its highly ... designed for endoscopy environments. An innovative secondary monitor solution, ZeroWire ... support the improvement of patient outcomes, procedural efficiency, and the lowering ... ... ...
(Date:10/4/2017)... 4, 2017  South Korean-based healthcare product Development Company ... "cprCUBE" on Kickstarter. The device will educate the user ... with better efficiency compared to the dated and pricey ... on efficacy of the compression for a more informed ... goal to raise $5,000. ...
(Date:10/2/2017)... 2017  Eli Lilly and Company (NYSE: ... third quarter of 2017 on Tuesday, October 24, 2017. ... day with the investment community and media to further ... call will begin at 9 a.m. Eastern time. Investors, ... webcast of the conference call through a link that ...
Breaking Medicine Technology: