Navigation Links
Geisel researchers sift through 'junk' to find colorectal cancer clues
Date:5/3/2012

he tumor samples were taken from patients at various stages of disease, adding to the strength of the finding.

Moore, who is also the associate director for bioinformatics at the Norris Cotton Cancer Center, adds that what he and Cowper-Sal.lari added to the study was their ability to make sense of mountains of data by developing computer programs and algorithms.

"It's an exciting time in cancer research because we can now sequence entire human genomes and measure the genome on a massive scale, but what's lagging behind are the computational methodsthe software, the algorithms, the statistical approachesto allow us to make sense of this vast amount of information," Moore says. "The DNA sequencing technology to generate the data is moving a lot faster than the computational methods for making sense of it."

Cowper-Sal.lari adds that the intense computation required to do the analysis was only possible because of access to DiscoveryDartmouth's supercomputing cluster.

There are a number of directions the research could go in the future. Cowper-Sal.lari says that if they are able to look at additional samples and find the same patterns, then "the genes that are the targets of these VELs are going to be really good potential therapeutic targets for colorectal cancer."

"That's the ultimate goalto develop drugs," Moore says. "If we can understand the biology of how these genes are turned on and off in cancer, then we can develop drugs to target them and turn them on or off."


'/>"/>

Contact: Derik Hertel
derik.hertel@dartmouth.edu
603-650-1211
Dartmouth College
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Researchers map all the fragile sites of the yeast Saccharomyces cerevisiaes genome
2. UH Case Medical Center researchers publish promising findings for advanced cervical cancer
3. Researchers discover new way to kill pediatric brain tumors
4. Researchers Who Discovered First Genes for Stuttering will Present Findings to the National Stuttering Association
5. Researchers create drug to keep tumor growth switched off
6. Urine protein test might help diagnose kidney damage from lupus, UT Southwestern researchers find
7. GUMC researchers say flower power may reduce resistance to breast cancer drug tamoxifen
8. Clemson researchers develop hands-free texting application
9. Researchers find biomarkers in saliva for detection of early-stage pancreatic cancer
10. Researchers chart genomic map spanning over 2 dozen cancers
11. Researchers discover second protective role for tumor-suppressor
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Geisel researchers sift through 'junk' to find colorectal cancer clues
(Date:1/22/2015)... with its top dressmaking technologies, has been a leading dress ... its latest designs of wedding dresses and launching a site-wide ... all the fresh new products are designed for 2015, and ... off. All the clothes from LunaDress follow up with the ...
(Date:1/22/2015)... VogueQueen is a seasoned and trusted leader who consistently delivers ... to have it lead the wedding dress industry into the ... dresses for the global market. , “The CEO of VogueQueen ... focuses on continuing the goal of operational excellence and giving ...
(Date:1/22/2015)... The federal court overseeing thousands of vaginal mesh ... District of West Virginia has upheld a $2 million verdict ... trial. In an Order dated January 21st, the Court denied ... C.R. Bard had not proven a miscarriage of justice. (Cisson ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 For over 20 years, ... Oceanside and Vista area has treated just about every ... personal injury circumstances. And for those same twenty-plus years, the ... of all those injuries with the best possible doctor. ...
(Date:1/22/2015)... (PRWEB) January 23, 2015 Recently, Weddingshe.com has ... catalog, and has announced its highest annual revenues in the ... on its popular glamorous wedding dresses. , According to the ... important wedding dress promotions for them in 2015. This point ...
Breaking Medicine News(10 mins):Health News:LunaDress Shows The Latest Styles Of Wedding Dresses In 2015 2Health News:VogueQueen Unveils New Designs of Prom Dresses for 2015 2Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 2Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 3Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 4Health News:Industry Leading Chiropractor in Oceanside Joins the Doctors on Liens Network 2Health News:Weddingshe Announces A Special Offer On Its Popular Glamorous Wedding Dresses 2
... A diet that is high on fiber is perhaps ... especially in offsetting hemorrhoids. // Hemorrhoids, a condition characterized ... anus that can give rise to bleeding and uneasiness. ... Rectal Surgeons, hemorrhoids can be caused by a variety ...
... has created history by running over such long distances may ... District// Child Welfare Committee chairman R S Mishra. ... to Orissa Women and Child Welfare Minister Pramila Mallick. "The ... a long distance", he said. He added that the proposed ...
... near normal lung function and seem to perform lung ... patients//. Similarly, male lung cancer patients were likely to ... is characterized by progressive deterioration in lung function. The ... CHEST journal, a publication of the American College of ...
... variations among different states with urban states getting more ... the smallest firms (1-9 workers) pay an average 18% ... largest firms (1,000+ workers), when actuarial value--the percentage of ... into account, a new Commonwealth Fund-supported study finds. ...
... drug that can treat breast cancer. But NHS said that it ... breast cancer. // Due to this there are lots of legal ... to pay for the drug. The latest being a British man, ... told that his local NHS trust would fund for his treatment ...
... East the health service is losing more than ?50m because ... ,Despite years of similar complaint by NHS managers the situation ... Hospital in Huntingdon said: ‘Some people do not turn up ... cause us a lot of problems in lost capacity and ...
Cached Medicine News:Health News:Male Lung Cancer Patients Less Likely To Perform Well in Lung Function Tests 2Health News:Health Insurance Plans Varies among States 2Health News:Health Insurance Plans Varies among States 3
(Date:1/23/2015)... 23, 2015   Leatt Corporation  (OTCQB: LEAT), a global ... all forms of sports, including extreme motor sports, and ... today that the UISP Lega Motociclismo Lombardia, an Italian ... to wear a neck brace during its racing competitions.  ...
(Date:1/23/2015)... , Jan. 23, 2015 Gem Pharmaceuticals announced ... have been enrolled into the Company,s Phase 2 clinical ... safety of Gem,s lead compound, GPX-150 (an investigational medication), ... or metastatic disease. Logo - http://photos.prnewswire.com/prnh/20150123/170966LOGO ...
(Date:1/22/2015)... , Jan. 22, 2015  ViewRay™, a privately held ... into an exclusive distributor agreement with ITOCHU Corporation (Tokyo ... therapy system for the treatment of cancer in ... system, is the world,s first and only MRI-guided radiation ...
Breaking Medicine Technology:Leatt Announces Neck Braces Now Required For Motocross/Minicross Racing In Italy 2Leatt Announces Neck Braces Now Required For Motocross/Minicross Racing In Italy 3Gem Pharmaceuticals Announces Enrollment of Initial Patients in its Phase 2 Clinical Trial to Assess the Efficacy and Safety of GPX-150 in Sarcoma Patients 2ITOCHU Named the Exclusive Distributor for ViewRay's MRI-Guided Radiation Therapy System in Japan 2
... presented at the 43rd European Association for the Study of ... ... presented,today at the 43rd Annual Meeting of the European Association for ... the risk of ischemic cardiovascular disease in patients with type 2,diabetes. ...
... Sept. 18 A long-term study found,that a ... with life-threatening,diseases, such as leukemia and lymphoma, results ... males are likely to recover,from these changes over ... In addition, neither male nor female long-term cancer,survivors ...
Cached Medicine Technology:ACTOS(R) (pioglitazone HCl) Demonstrates Reduced Risk of Ischemic Cardiovascular Disease in Patients with Type 2 Diabetes 2ACTOS(R) (pioglitazone HCl) Demonstrates Reduced Risk of Ischemic Cardiovascular Disease in Patients with Type 2 Diabetes 3Sexual Function Affected by Stem Cell Transplant According to Long-Term Study 2Sexual Function Affected by Stem Cell Transplant According to Long-Term Study 3Sexual Function Affected by Stem Cell Transplant According to Long-Term Study 4
The screening test for colorectal cancer that's simple, convenient, and effective....
A rapid, convenient, qualitative method for detecting asymptomatic occult bleeding....
... 500,000 people die each year of ... Despite diagnostic improvements (high contrast berium ... an increase in the success rate ... has not been achieved over the ...
... of guaiac as a test for the presence ... phenolic compounds present in guaiac to quinones, resulting ... blood is present, the heme portion of the ... catalyzing the release of oxygen from hydrogen peroxide ...
Medicine Products: