Navigation Links
Gecko's Stickiness Inspires New Surgical Bandage
Date:2/19/2008

It's waterproof, biodegradable and adheres much better than conventional sutures, researchers say

TUESDAY, Feb. 19 (HealthDay News) -- Borrowing a design from the agile, sticky-footed gecko, scientists have created a waterproof, biodegradable adhesive bandage that may one day replace conventional sutures.

The bandage, which could close external wounds and mend internal injuries, has tiny "hills and valleys," similar to those found on the gecko's feet, a Harvard-MIT team reports. This bit of natural engineering allows geckos to cling to almost any surface, even upside-down.

Overlaying the clingy structures is a coating of glue that enables the new bandage to stick onto wet tissues. That ability to stick in wet conditions has been a major challenge to overcome, the researchers said.

"There is a big need for bondable, tape-based adhesives that could be used to seal tissues," said lead researcher Jeffrey M. Karp, director of the Laboratory for Advanced Biomaterials and Stem Cell-Based Therapeutics at the Harvard-MIT Division of Health Sciences and Technology at Brigham and Women's Hospital in Boston.

His team described the new bandage in this week's online edition of the Proceedings of the National Academy of Sciences.

There are other glue-based surgical tapes available, but many are neither flexible nor waterproof, Karp noted. "We decided we needed to create a new material that was elastic, that could conform to the tissue and that could be biodegradable," he said. "So we created this new material that met all of these requirements."

To design a material that could adhere to slippery tissues, the researchers turned to one of nature's stickiest creatures, the gecko. The gecko is able to cling to walls and ceilings using tiny corrugated structures called "nanoscale pillars" on its paws.

"The gecko has no glue, but it uses nanoscale pillars -- a whole carpet of them, millions of them, to adhere to a surface," Karp said. "We decided we could incorporate nanostructures in the surface of our material to enhance the adhesion," he said.

According to the researchers, the new bandage is also biodegradable and dissolves over time, so it wouldn't have to be surgically removed. The amount of time the tape needs to biodegrade can be programmed for specific applications, Karp noted.

Ideally, this type of adhesive bandage should also prevent leaks and deliver drugs for long term, similar to a skin patch, Karp said. He envisions the new adhesive tape being used in hernia surgery, gastric bypass surgery, surgery to remove part of the colon in Crohn's disease and many other invasive procedures. The tape could also be used to seal holes in the bladder or holes caused by ulcers.

"In addition, we believe that these tapes can also be used as a general internal drug-delivery patch to deliver anti-inflammatories, antibiotics or growth factors to encourage healing," Karp said.

The new product could someday replace sutures or staples in some circumstances, such as minimally invasive surgery, Karp said. Because the tape can be folded and unfolded, it could be used in procedures that are difficult to suture because they are performed through a very small incision, he noted.

So far, Karp's team has demonstrated their tape on pig intestine and has implanted the product in the stomachs of rats. When used with pig intestine, the new tape was twice as strong as tape that did not have the nanoscale pillars. In rats, the new tape increased adhesive strength by 100 percent compared with material lacking the nanoscale pillars.

The researchers are now at the point of designing adhesives for specific tissues, because each tissue type is distinct, Karp said. They then hope to start testing the gecko-inspired adhesive in clinical trials.

More information

For more on sutures, visit the University of Illinois Medical Center.



SOURCES: Jeffrey M. Karp, Ph.D., director, Laboratory for Advanced Biomaterials and Stem Cell-Based Therapeutics, Harvard-MIT Division of Health Sciences and Technology, Cambridge, Mass.; Feb. 18, 2008, online issue, Proceedings of the National Academy of Sciences


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Reunion with patient inspires follow-up study on treatment for DiGeorge syndrome
2. After Dropping 162 Pounds, Jodi Davis Inspires Other Michigan Women to Get Moving and Lose Weight Through WalkyTalk.com(TM)
3. Botox Cosmetic Alternatives Are Available: Surgical Procedures Offer Solution for Wrinkles
4. PEAK Surgical, Inc. Closes $21 Million Series C Financing
5. Thought Leaders in Morbid Obesity Treatment Convene at Upcoming Surgical Conference
6. Surgical site infections more common than expected following breast procedures
7. STAAR Surgical to Present at the Tenth Annual Needham Growth Conference
8. Older surgical patients at greater risk for developing cognitive problems
9. Surgical Care Affiliates and UCSD Medical Center to Partner in Surgical Center
10. Early surgical treatment contributes to better outcomes in gallstone pancreatitis cases
11. Robotic device appears useful for surgical removal of cancer involving the tonsils
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Gecko's Stickiness Inspires New Surgical Bandage
(Date:2/7/2016)... Orion, Clarkston, Metamora, Michigan (PRWEB) , ... February 07, 2016 , ... ... Friday in recognition of National Wear Red Day. National Wear Red Day is ... and stroke in women. Heart disease and stroke cause 1 in 3 deaths among ...
(Date:2/6/2016)... ... February 06, 2016 , ... ... ADVISORY: 5000 PERIOPERATIVE NURSES EXPECTED AT AORN SURGICAL CONFERENCE & EXPO , ... the world with an estimated 5000 perioperative nurses in attendance to study ...
(Date:2/6/2016)... ... February 06, 2016 , ... Shark Finds and Kevin ... of a new DRTV campaign with Belly Bands. , Having a dog is great—except ... to puppy pads and find nothing works, get Belly Bands, the easiest way ...
(Date:2/5/2016)... ... 05, 2016 , ... Love is in the air at King Kullen! The ... and packaging. This staple for Valentine’s Day is a must-have, and can be picked ... Day, not only are long-stem roses available, but also other flower bouquets, elegantly wrapped ...
(Date:2/5/2016)... , ... February 05, 2016 , ... ... setting the stage for new clinical and scientific initiatives have all marked the ... she was appointed President and CEO of the nation’s oldest cancer center, Candace ...
Breaking Medicine News(10 mins):
(Date:2/4/2016)... , Feb. 4, 2016 In response to the ... FDA,s Deputy Commissioner for Medical Products and Tobacco, along with ... reassess the agency,s approach to opioid medications. The plan will ... providing patients in pain access to effective relief. ... , Re-examine the risk-benefit paradigm for opioids and ...
(Date:2/4/2016)...  Blueprint Medicines Corporation (NASDAQ: BPMC ), ... investigational kinase medicines for patients with genomically defined ... of directors of Lonnel Coats , a ... industry-related experience. Jeffrey Albers , ... strategic experience developing and commercializing numerous oncology products ...
(Date:2/4/2016)... SIOUX FALLS, S.D. , Feb. 4, 2016 ... patient and guest technology solutions, today announced that ... SONIFI Health Senior Living Engagement System. The system ... information tool that residents access through a tablet ... --> The resident engagement system provides access ...
Breaking Medicine Technology: