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Gauging Brain Cancer Survival Time May Get Easier: Study
Date:4/10/2013

emotherapy. The overactive enzyme also interferes with a protein, called cytochrome c, that triggers the self-destruction of cells infected or damaged by diseases such as cancer. When this happens, cancer cells can survive an abnormally long time.

But the researchers aren't stopping with this finding. "Giving some GBM patients bad news about their prognoses without also giving them better treatment options doesn't seem right to me," said Griguer, noting that the team is experimenting with another enzyme to try to predict patients' survival benefit from the chemo drug temozolomide.

"Our ultimate goal is to use the same mechanism that predicts shorter survival in some to design drugs that target cells not killed right away by chemotherapy," she said.

More information

The U.S. National Institutes of Health provides more information on brain cancer.

-- Mary Elizabeth Dallas

SOURCE: University of Alabama at Birmingham, news release, April 10, 2013


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