Navigation Links
GW researchers: Acute kidney injury and chronic kidney disease as interconnected syndromes
Date:7/3/2014

WASHINGTON (July 3, 2014) For more than 40 years, physicians have treated diminished kidney function as two distinct syndromes: acute kidney injury (AKI) and chronic kidney disease (CKD). However, recent epidemiologic and mechanistic studies suggest the two syndromes are not distinct entities, but interconnected. Published today in The New England Journal of Medicine, George Washington University (GW) researchers call for greater follow-up care of patients with AKI, who often present with CKD later in life, and vice versa.

"Our teaching has been wrong and the approach to the patient with decreased renal function has been too limited. Every doctor who sees patients with CKD should think about AKI and every doctor who sees a patient with AKI, should think about CKD as a possible sequel of AKI," said Paul Kimmel, M.D., clinical professor of medicine at the GW School of Medicine and Health Sciences (SMHS). "Our review article is written for surgeons, for general internists, for pediatricians, for orthopedists anyone who takes care of patients, because AKI is such a common problem."

AKI, previously called acute renal failure, is often the result of crush injury, a side effect of drugs, or severe infection, and defined as a sudden increase in the serum creatinine concentration and decreased urine output. After recovery, patients receive little to no follow-up care by nephrologists. CKD often lasts a long time, changes slowly, and culminates in dialysis or renal transplantation.

In the article, Kimmel and his co-author, Lakhmir Chawla, M.D., associate professor of anesthesiology and critical care medicine at SMHS and physician at the VA Medical Center, outline several findings suggesting that AKI not only is directly linked to the progression of CKD, but can actually cause CKD. Conversely, the presence of CKD is an important risk factor for the development of AKI. Both AKI and CKD have bad outcomes most particularly, cardiovascular disease.

"We need to start with a deeper sense of awareness for physicians, improving the follow-up care of patients who suffer from AKI, which is currently not done very well," said Chawla. "It's not like someone who has a heart attack, where that person will be seen by a cardiologist a couple weeks after they're discharged. A very small percentage of patients who suffer from AKI are seen by a nephrologist after the initial events."


'/>"/>

Contact: Lisa Anderson
lisama2@gwu.edu
202-270-4841
George Washington University
Source:Eurekalert

Related medicine news :

1. Moffitt Cancer Center researchers: Quality of life as important as quantity of life
2. Moffitt researchers: Darwins principles say cancer will always evolve to resist treatment
3. UI researchers: Bracing is effective in adolescents with idiopathic scoliosis
4. Researchers: Biomarkers predict effectiveness of radiation treatments for cancer
5. Long-term neuropsychological impairment is common in acute lung injury survivors
6. Predictors identified for rehospitalization among post-acute stroke patients
7. Original research papers on acute cardiovascular care: ESC launches EHJ-ACVC
8. A microRNA prognostic marker identified in acute leukemia
9. 4 acute mushroom poisonings in 2 weeks
10. Scientists identify possible drug target for acute pancreatitis
11. Inhibitors of shuttle molecule show promise in acute leukemia
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/13/2016)... ... ... DDi , a Makro company, makes it to ... in eClinical Solutions. DDi has built its solution competency with a unique blend ... DDi provides smarter technology for Clinical Development, Regulatory and Enterprise domains by providing ...
(Date:2/12/2016)... , ... February 12, 2016 , ... ... devoted exclusively to funding innovative lymphoma research and serving the lymphoma community through ... over 250 members of South Florida’s philanthropic community at its 10th anniversary Fashion ...
(Date:2/12/2016)... ... 2016 , ... Coco Libre, the maker of coconut water beverages with a ... Lounge Event. Coco Libre will offer musicians and celebrities the company’s signature Organic Coconut ... invitation-only gifting suite, held this year at the W Hollywood Hotel, has become a ...
(Date:2/12/2016)... ... February 12, 2016 , ... Fisher House Foundation Chairman ... John J. Lee, Nevada Military Support Alliance president Scott Bensing, and Peggy Kearns Director, ... VA Southern Nevada Healthcare System. This will be the first Fisher House in ...
(Date:2/12/2016)... ... February 12, 2016 , ... Young ... area, celebrates the beginning of the latest charity campaign in their community enrichment ... art. Donations to this worthy cause are currently being accepted at: http://artexpressioninc.org/ ...
Breaking Medicine News(10 mins):
(Date:2/12/2016)... , Kalifornien, 12. Februar 2016  Sequent ... der Aufnahme von Patienten für eine Studie zur ... Aneurysmen („WEB") speziell für die Behandlung von rupturierten ... , MD, Leiter der Neuroradiologie an der Universitätsklinik ... und Hauptprüfarzt der CLARYS-Studie hat den ersten Patienten ...
(Date:2/12/2016)... , Feb. 12, 2016  Eli Lilly and Company ... Court decided the Alimta® (pemetrexed disodium) vitamin regimen patent would ... the UK, France , Italy ... to dilute the product only with dextrose solution.  ... 2015, the UK Court of Appeal held that Lilly,s patent ...
(Date:2/12/2016)... BUDAPEST , Ungarn, February 12, 2016 ... ein Medizintechnikunternehmen, das sich auf den ungedeckten ... gab heute positive Ergebnisse seines klinischen Forschungsprogramms ... und Asthma-Patienten beschäftigt, ergab Verbesserungen ihrer respiratorischen ... Indiso ltd , ein Medizintechnikunternehmen, das ...
Breaking Medicine Technology: