Navigation Links
GW researcher studies the effects of BPA and DEHP on the cardiovascular system
Date:5/5/2014

WASHINGTON (May 5, 2014) Nikki Posnack, Ph.D., a post-doctoral pharmacology and physiology researcher at the George Washington University School of Medicine and Health Sciences (SMHS), received a $209,926 grant from the National Institute of Environmental Health Sciences to study plastics and their potential human health risks, particularly in the cardiovascular system. This grant will support the study of two chemicals found in plastic products: bisphenol A (BPA) and di-2-ethylhexylphthalate (DEHP).

Over the next few years, Posnack will study these endocrine-disrupting compounds (EDCs) to determine whether they can interfere with the homeostatsis, or internal stability, of the cardiovascular system. She will also study whether EDCs affect the mechanical function of excised hearts, expanding on her previous research finding that BPA exposure slowed electrical conduction in these hearts.

While there are many BPA-free and phthalate-free plastics, these compounds are still found in many consumer products, including food containers, toys, and medical devices. As a result, exposure to EDCs has become virtually continuous and essentially unavoidable, a fact highlighted by human biomonitoring studies. Of particular concern are the high levels of exposure experienced by industrial workers and infants in Neonatal Intensive Care Units.

"The one thing we are trying to get to the bottom of is whether BPA is toxic or not," said Posnack. "There are groups on both sides, offering different conclusions, often depending on funding. Some researchers have seen correlations between BPA and cardiovascular disease. We are trying to find out whether real concentrations of the chemicals people are exposed to might cause an adverse cardiac effect. We hope to find out definitively whether this is or is not a concern."

This grant will include research into prenatal exposure to these chemicals, as well as the effects of BPA and DEHP on animals that have undergone heart failure or cardiac injury.

This prestigious two-part transitional award is a National Institutes of Health Pathway to Independence Award, also known as a K99 grant, which will later transition to a R00 grant. While SMHS has several R00 recipients, Posnack is the first to have received this award at the K99 level.


'/>"/>

Contact: Lisa Anderson
lisama2@gwu.edu
202-994-3121
George Washington University
Source:Eurekalert

Related medicine news :

1. NIH awards $20 million over 5 years to train next generation of global health researchers
2. Researchers develop a new cell and animal model of inflammatory breast cancer
3. Researchers uncover a viable way for colorectal cancer patients to overcome drug resistance
4. Researchers Find Gene Mutations That May Be a Key to Autism
5. Researchers find evidence of banned antibiotics in poultry products
6. NJ stroke researchers report advances in spatial neglect research at AAN Conference
7. Autism by the numbers: Yale researchers examine impact of new diagnostic criteria
8. Stress contributes to cognitive declines in women with breast cancer, researcher says
9. Researchers Map Brain Regions Linked to Intelligence
10. Researchers ID Genes That May Determine Mental Illness
11. Researchers Develop Blood Test for Depression
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... California (PRWEB) , ... June 25, 2016 , ... "With ... fit their specific project," said Christina Austin - CEO of Pixel Film Studios. ... customizable and all within Final Cut Pro X . Simply select a ProHand ...
(Date:6/25/2016)... Canada (PRWEB) , ... June 25, 2016 , ... Conventional ... pursuit of success. In terms of the latter, setting the bar too high can ... risk more than just slow progress toward their goal. , Research from ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Pulmonary Hypertension ... that it will receive two significant new grants to support its work to ... its 25th anniversary by recognizing patients, medical professionals and scientists for their work ...
(Date:6/24/2016)... ... , ... People across the U.S. are sharpening their pencils and honing their ... in which patients and their families pay tribute to a genetic counselor by nominating ... of Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. , In April, ...
(Date:6/24/2016)... ... ... recruitment firm Slone Partners is pleased to announce the placement of Suzanne ... of North American Capital Sales at HTG Molecular . , In ... commercialization of the HTG EdgeSeq system and associated reagents in North America. , Headquartered ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... , June 26, 2016 ... value-based care operating models within the health care industry ... greater financial efficiency , Deloitte offers a suite ... key business issues impacting efficient cost optimization: labor resource ... , These services facilitate better outcomes and better economics ...
(Date:6/24/2016)... SAN FRANCISCO, Calif. , June 24, 2016 ... GBT ), a biopharmaceutical company developing novel therapeutics ... significant unmet needs, today announced the closing of ... shares of common stock, at the public offering ... shares in the offering were offered by GBT. ...
(Date:6/24/2016)... 24, 2016 Research and ... "Structural Electronics 2015-2025: Applications, Technologies, Forecasts" report ... In-Mold Electronics, Smart Skin, Structural Health Monitoring, ... Structural electronics involves electronic and/or electrical components ... replacing dumb structures such as vehicle bodies or ...
Breaking Medicine Technology: