Navigation Links
GW researcher receives $4.1 million grant to find alternative treatment for kidney stones
Date:11/14/2012

WASHINGTON (Nov. 14, 2012) In the United States, one in 10 men and one in 14 women have had a kidney stone. Unless the kidney stone is too large to pass on its own, the treatment prescribed is usually plenty of fluids and painkillers while letting it pass over a period of several days. Jeremy Brown, M.D., associate professor of emergency medicine at the George Washington University (GW) School of Medicine and Health Sciences, has received a grant that will ideally give this increasingly large group of patients more options with fewer complications.

Brown received a four-year, $4,198,046 cooperative agreement research project grant from the National Institutes of Health (NIH) and the National Institute of Diabetes and Digestive and Kidney Diseases to explore new ways to treat kidney stones. His research project, titled "Multi-Center Study of Tamsulosin for Ureteral Stones in the Emergency Department," will enroll patients with kidney stones in three Emergency Departments (EDs), including the ED at GW, and randomize them to either an active medication called Tamsulosin or a placebo.

"I originally became interested in this because I saw Tamsulosin being used by some urologists," said Brown. "I realized it hadn't actually been studied in a rigorous way."

Brown began studying the effects of Tamsulosin as a treatment option for kidney stones with a small-scale study at GW funded by the NIH. After the successful completion of this study, Brown submitted a proposal for a larger study that would include additional EDs. The three EDs included in the study are those of GW, the University of Pennsylvania, and the University of Pittsburgh. Patients who present with kidney stones will receive the usual treatment pain medications, CT scans, and fluids and will then be asked if they would like to be enrolled in the study. If enrolled in the double blind study, they will be randomly assigned to receive either Tamsulosin or a placebo. Brown and his research team will then call to check up on the patient during the first month and after three months to determine whether they had any complications and how quickly the stone passed.

Brown believes treatment with Tamsulosin may help patients pass their kidney stones faster and with fewer complications.

"In terms of the patient, the best case scenario would be that this medication helps get kidney stones out sooner, so they are out of pain quicker and with fewer complications," said Brown. "That way, they can get off pain medications, which are usually quite strong, and get back to normal living."


'/>"/>

Contact: Lisa Anderson
lisama2@gwu.edu
202-994-3121
George Washington University
Source:Eurekalert

Related medicine news :

1. NIH awards $20 million over 5 years to train next generation of global health researchers
2. Researchers develop a new cell and animal model of inflammatory breast cancer
3. Researchers uncover a viable way for colorectal cancer patients to overcome drug resistance
4. Researchers Find Gene Mutations That May Be a Key to Autism
5. Researchers find evidence of banned antibiotics in poultry products
6. NJ stroke researchers report advances in spatial neglect research at AAN Conference
7. Autism by the numbers: Yale researchers examine impact of new diagnostic criteria
8. Stress contributes to cognitive declines in women with breast cancer, researcher says
9. Researchers Map Brain Regions Linked to Intelligence
10. Researchers ID Genes That May Determine Mental Illness
11. Researchers Develop Blood Test for Depression
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... , ... June 25, 2016 , ... ... and non-athletes recover from injury. Recently, he has implemented orthobiologic procedures as a ... area —Johnson is one of the first doctors to perform the treatment. Orthobiologics ...
(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the benefits ... terms of the latter, setting the bar too high can result in disappointment, perhaps ... slow progress toward their goal. , Research from PsychTests.com reveals that ...
(Date:6/24/2016)... ... ... Those who have experienced traumatic events may suffer from a complex set ... drug or alcohol abuse, as a coping mechanism. To avoid this pain and suffering, ... traumatic event. , Trauma sufferers tend to feel a range of emotions, from depression, ...
(Date:6/24/2016)... CA (PRWEB) , ... June 24, 2016 , ... Marcy was in a crisis. Her ... would lash out at his family verbally and physically. , “When something upset him, he ... he would use it. He would throw rocks at my other children and say he ...
(Date:6/24/2016)... ... June 24, 2016 , ... Global law firm Greenberg Traurig, P.A. ... The attorneys chosen by their peers for this recognition are considered among the top ... Shareholders received special honors as members of this year’s Legal Elite Hall of Fame: ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , Belgium , June 24, ... VNRX), today announced the appointment of Dr. ... Directors as a Non-Executive Director, effective June 23, ... Audit, Compensation and Nominations and Governance Committees.  As ... Futcher will provide independent expertise and strategic counsel ...
(Date:6/23/2016)... Research and Markets has announced the addition of ... report to their offering. ... kidney failure, it replaces the function of kidneys by removing ... thus the treatment helps to keep the patient body,s electrolytes ... Increasing number of ESRD patients & substantial healthcare expenditure ...
(Date:6/23/2016)... , June 23, 2016  In a startling report released ... failing their residents by lacking a comprehensive, proven plan to eliminate ... a definitive ranking of how states are tackling the worst drug ... only four states – Kentucky , ... Vermont . Of the 28 failing states, three – ...
Breaking Medicine Technology: