Navigation Links
GW researcher receives $4.1 million grant to find alternative treatment for kidney stones
Date:11/14/2012

WASHINGTON (Nov. 14, 2012) In the United States, one in 10 men and one in 14 women have had a kidney stone. Unless the kidney stone is too large to pass on its own, the treatment prescribed is usually plenty of fluids and painkillers while letting it pass over a period of several days. Jeremy Brown, M.D., associate professor of emergency medicine at the George Washington University (GW) School of Medicine and Health Sciences, has received a grant that will ideally give this increasingly large group of patients more options with fewer complications.

Brown received a four-year, $4,198,046 cooperative agreement research project grant from the National Institutes of Health (NIH) and the National Institute of Diabetes and Digestive and Kidney Diseases to explore new ways to treat kidney stones. His research project, titled "Multi-Center Study of Tamsulosin for Ureteral Stones in the Emergency Department," will enroll patients with kidney stones in three Emergency Departments (EDs), including the ED at GW, and randomize them to either an active medication called Tamsulosin or a placebo.

"I originally became interested in this because I saw Tamsulosin being used by some urologists," said Brown. "I realized it hadn't actually been studied in a rigorous way."

Brown began studying the effects of Tamsulosin as a treatment option for kidney stones with a small-scale study at GW funded by the NIH. After the successful completion of this study, Brown submitted a proposal for a larger study that would include additional EDs. The three EDs included in the study are those of GW, the University of Pennsylvania, and the University of Pittsburgh. Patients who present with kidney stones will receive the usual treatment pain medications, CT scans, and fluids and will then be asked if they would like to be enrolled in the study. If enrolled in the double blind study, they will be randomly assigned to receive either Tamsulosin or a placebo. Brown and his research team will then call to check up on the patient during the first month and after three months to determine whether they had any complications and how quickly the stone passed.

Brown believes treatment with Tamsulosin may help patients pass their kidney stones faster and with fewer complications.

"In terms of the patient, the best case scenario would be that this medication helps get kidney stones out sooner, so they are out of pain quicker and with fewer complications," said Brown. "That way, they can get off pain medications, which are usually quite strong, and get back to normal living."


'/>"/>

Contact: Lisa Anderson
lisama2@gwu.edu
202-994-3121
George Washington University
Source:Eurekalert

Related medicine news :

1. NIH awards $20 million over 5 years to train next generation of global health researchers
2. Researchers develop a new cell and animal model of inflammatory breast cancer
3. Researchers uncover a viable way for colorectal cancer patients to overcome drug resistance
4. Researchers Find Gene Mutations That May Be a Key to Autism
5. Researchers find evidence of banned antibiotics in poultry products
6. NJ stroke researchers report advances in spatial neglect research at AAN Conference
7. Autism by the numbers: Yale researchers examine impact of new diagnostic criteria
8. Stress contributes to cognitive declines in women with breast cancer, researcher says
9. Researchers Map Brain Regions Linked to Intelligence
10. Researchers ID Genes That May Determine Mental Illness
11. Researchers Develop Blood Test for Depression
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/12/2016)... ... February 12, 2016 , ... CDRH Enforcement Trends: , Back to the Future , Feb. ... , As Winston Churchill said, “Those who don’t learn from history are doomed to repeat ... when they come knocking this year. But that takes time. , Take a close ...
(Date:2/12/2016)... ... ... Each year, the American Physical Therapy Association (APTA) offers a Combined Sections ... Center. Almost 10,000 physical therapists across the country are expected to attend this annual ... chosen field and network with their colleagues. As in years past, HydroWorx is ...
(Date:2/12/2016)... ... , ... Coco Libre, the maker of coconut water beverages with a purpose, ... Event. Coco Libre will offer musicians and celebrities the company’s signature Organic Coconut Water, ... gifting suite, held this year at the W Hollywood Hotel, has become a pre-show ...
(Date:2/12/2016)... ... February 12, 2016 , ... The ThedaCare Center for Healthcare ... Hospital on April 5-7. The series is a multi-day, multi-workshop event designed to ... cover a broad range of topics, including coaching skills, the scientific method of ...
(Date:2/12/2016)... PITTSBURGH, Pa. (PRWEB) , ... February 12, 2016 , ... ... space heaters. , This winter the West Penn Burn Center, part of ... Fire Company #1, to bring you the “Space Heaters Need Space” campaign. ...
Breaking Medicine News(10 mins):
(Date:2/11/2016)...  Kindred Biosciences, Inc. (NASDAQ: KIN ), a ... of pets, today announced the submission to FDA of ... Application (NADA) for Zimeta™ (dipyrone injection, KIND-012).  Positive topline ... for the control of pyrexia (fever) in horses were ... --> The Chemistry, Manufacturing, and Controls ...
(Date:2/11/2016)...   Health 2.0 , the premiere showcase and ... today " 10 Year Global Retrospective ", a platform ... past ten years.   --> ... has served as the preeminent thought-leader in the health ... technologies, companies, innovators, and patient-activists through an array of ...
(Date:2/11/2016)... , Feb. 11, 2016  MiMedx Group, Inc. (NASDAQ: ... human amniotic membrane and other birth tissues, human skin ... develop and market advanced products and therapies, announced today ... 2016 Global Healthcare Conference in New York ... CEO, Michael J. Senken , Chief Financial Officer ...
Breaking Medicine Technology: