Navigation Links
GI Bleeding After Stroke Raises Death Risk
Date:8/6/2008

Triples mortality rate while still in hospital, study finds

WEDNESDAY, Aug. 6 (HealthDay News) -- Stroke patients who develop gastrointestinal bleeding while in recovery are three times as likely to die in the hospital or be heavily disabled upon release than those who do not, a new Canadian study suggests.

The finding is based on an analysis of patients who were observed while in recovery from an ischemic stroke. Ischemic strokes are the most common type of stroke -- resulting from a slowdown or blockage of blood to the brain.

"We found that the actual incidence of gastrointestinal [GI] bleeding would make it an uncommon complication," said study author Dr. Martin O'Donnell, an associate professor in the department of medicine at McMaster University in Hamilton, Ontario. "But when it does arise, it appears to be associated with increased death and disability."

O'Donnell and his colleagues are publishing their findings in the Aug. 6 online issue of Neurology.

The authors focused on just over 6,800 men and women admitted to 11 Ontario hospitals between 2003 and 2006 following an acute ischemic stroke.

Of these patients, 829 died during their hospital stay, and 1,374 passed away within six months of their stroke.

Just 1.5 percent -- or 100 patients -- had bleeding in their stomach or intestine during their hospitalization. These patients were evenly split among men and women, and more than half had experienced a mild or moderate stroke, the research team noted.

Aside from a tripling of mortality in the hospital, stroke patients with GI bleeding were also 1.5 times more likely to die within a half-year of their stroke than those with no such complication. This observation held up even after accounting for other factors that could contribute to mortality, such as pneumonia and heart attacks.

O'Donnell noted that the relatively small number of patients he and his team tracked makes it difficult to definitively identify what type of stroke patients are at highest risk for GI bleeding -- although that is something he and his colleagues hope to explore down the road. But meanwhile, he argued that the findings already highlight some critical issues concerning stroke recovery.

"One of the key points we want to raise is that people are generally prone to developing medical complications with stroke," he said. "And as part of that larger observation, we know that among these complications are GI issues. And we feel that this is particularly important, because gastrointestinal bleeding is a complication that is potentially modifiable with various treatment strategies."

However, both Dr. Matthew Fink, chief of the division of stroke and critical care neurology at Weill Cornell Medical College in New York City, and Dr. Larry B. Goldstein, director of The Stroke Center at Duke University Medical Center, expressed reservations about the findings.

"Having a poorer outcome in stroke patients with gastrointestinal bleeding is not surprising at all," said Goldstein. "But I don't know, based on this kind of a retrospective study, if we can tell how preventable this is, as there are all sorts of things that the researchers may not be measuring that might affect the results."

Fink agreed, while suggesting that the issue itself is not particularly pressing.

"In the U.S.," he noted, "we treat all our stroke patients with preventive prophylactic therapy to prevent GI bleeding, and our experience is that GI bleeding is a rare event. So, it's really not something we get too concerned about."

"And that means that the fact that this study shows an increased risk of death associated with GI bleeding says to me that a gastrointestinal problem is simply a marker for someone who is a lot sicker, not an independent factor directly related to the stroke itself," he said. "So, I don't think this finding gives us much useful new information."

More information

For more on post-stroke recovery, visit the National Stroke Association.



SOURCES: Martin O'Donnell, M.D., associate professor, department of medicine, McMaster University, Hamilton, Ontario, Canada; Matthew Fink, M.D., chief, division of stroke and critical care neurology, Weill Cornell Medical College, New York City; Larry B. Goldstein, M.D., director, The Stroke Center at Duke University Medical Center, Durham, N.C.; Aug. 6, 2008, Neurology, online


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Popular Antidepressants Linked to GI Bleeding
2. Bowel prep oral sodium phosphate equal to fasting before capsule endoscopy for obscure GI bleeding
3. Clot-Busting Treatment Improves Bleeding Stroke Outcomes
4. Researchers fine-tune clot-busting treatment for bleeding in brain
5. Noninvasive Procedures Show Promise for Esophageal Bleeding
6. Staff Training Reduces Postpartum Bleeding, Episiotomies
7. Viscosity Enhancers Curb Bleeding Complications
8. Smoking Boosts Bleeding Stroke Risk in Those With High Blood Pressure
9. Alcoholics underestimate the risk of bleeding
10. Anti-Clotting Drug Trial Shortened by Bleeding Problems
11. Research Highlights New Approaches to Management of Blood Clotting and Bleeding Disorders
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
GI Bleeding After Stroke Raises Death Risk
(Date:12/2/2016)... , ... December 02, 2016 , ... ... veterinarian diagnostic imaging systems and the first company to offer robotic imaging ... Heart at their tradeshow booth # 941 for the American Association of Equine ...
(Date:12/2/2016)... ... 2016 , ... Rijuven Corp launches rejiva ( http://www.rejiva.com ), a unique wearable ... wearable health technology on the market can deliver all that rejiva can. , “Rejiva ... about their health than the usual heart rate and steps taken”, adds Evens Augustin, ...
(Date:12/2/2016)... ... December 02, 2016 , ... "Pro3rd Accents Volume 2 is a ... versatile lower third titles with just a few clicks of the mouse," said Christina ... 30 lower third animations. Choose from various styles with accented animations, rigid boxes, simplistic ...
(Date:12/2/2016)... (PRWEB) , ... December 02, 2016 , ... ... hot meals to needy individuals and families from eight different sites throughout Miami-Dade ... Thanksgiving Day. Over 1,000 volunteers worked very hard on Thanksgiving morning by putting ...
(Date:12/2/2016)... (PRWEB) , ... December 02, 2016 , ... ... Technologist/Clinical Laboratory Scientist & Author of Type 2 Diabetes: The Owner’s Manual, ... The Sharon Kleyne Hour Power of Water, Global Climate Change and Your Health ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... Allergan plc (NYSE: AGN ), a ... previously announced Accelerated Share Repurchase (ASR) Program. Logo - ... ... previously announced, the Company entered into a variable tenor ASR ... repurchase $10 billion of its ordinary shares. Approximately 40.5 million ...
(Date:11/30/2016)... 2016 Research and Markets has ... Neuromodulation, Neurovascular, Neurosurgical and Monitoring Devices 2017 - MedView" ... ... The full report suite on the U.S. market for neurological ... intracranial pressure monitoring devices, detachable coils, liquid embolics, catheters, guidewires, ...
(Date:11/30/2016)... 2016 Varian Medical Systems (NYSE: ... JUST Company in the Healthcare Equipment and Services industry, ... inaugural "JUST 100 List." The rankings are based on ... conducted on attitudes towards corporate behavior, involving 50,000 Americans ... U.S companies against their peers within 32 major industries. ...
Breaking Medicine Technology: