Navigation Links
GI Bleeding After Stroke Raises Death Risk
Date:8/6/2008

Triples mortality rate while still in hospital, study finds

WEDNESDAY, Aug. 6 (HealthDay News) -- Stroke patients who develop gastrointestinal bleeding while in recovery are three times as likely to die in the hospital or be heavily disabled upon release than those who do not, a new Canadian study suggests.

The finding is based on an analysis of patients who were observed while in recovery from an ischemic stroke. Ischemic strokes are the most common type of stroke -- resulting from a slowdown or blockage of blood to the brain.

"We found that the actual incidence of gastrointestinal [GI] bleeding would make it an uncommon complication," said study author Dr. Martin O'Donnell, an associate professor in the department of medicine at McMaster University in Hamilton, Ontario. "But when it does arise, it appears to be associated with increased death and disability."

O'Donnell and his colleagues are publishing their findings in the Aug. 6 online issue of Neurology.

The authors focused on just over 6,800 men and women admitted to 11 Ontario hospitals between 2003 and 2006 following an acute ischemic stroke.

Of these patients, 829 died during their hospital stay, and 1,374 passed away within six months of their stroke.

Just 1.5 percent -- or 100 patients -- had bleeding in their stomach or intestine during their hospitalization. These patients were evenly split among men and women, and more than half had experienced a mild or moderate stroke, the research team noted.

Aside from a tripling of mortality in the hospital, stroke patients with GI bleeding were also 1.5 times more likely to die within a half-year of their stroke than those with no such complication. This observation held up even after accounting for other factors that could contribute to mortality, such as pneumonia and heart attacks.

O'Donnell noted that the relatively small number of patients he and his team tracked makes it difficult to definitively identify what type of stroke patients are at highest risk for GI bleeding -- although that is something he and his colleagues hope to explore down the road. But meanwhile, he argued that the findings already highlight some critical issues concerning stroke recovery.

"One of the key points we want to raise is that people are generally prone to developing medical complications with stroke," he said. "And as part of that larger observation, we know that among these complications are GI issues. And we feel that this is particularly important, because gastrointestinal bleeding is a complication that is potentially modifiable with various treatment strategies."

However, both Dr. Matthew Fink, chief of the division of stroke and critical care neurology at Weill Cornell Medical College in New York City, and Dr. Larry B. Goldstein, director of The Stroke Center at Duke University Medical Center, expressed reservations about the findings.

"Having a poorer outcome in stroke patients with gastrointestinal bleeding is not surprising at all," said Goldstein. "But I don't know, based on this kind of a retrospective study, if we can tell how preventable this is, as there are all sorts of things that the researchers may not be measuring that might affect the results."

Fink agreed, while suggesting that the issue itself is not particularly pressing.

"In the U.S.," he noted, "we treat all our stroke patients with preventive prophylactic therapy to prevent GI bleeding, and our experience is that GI bleeding is a rare event. So, it's really not something we get too concerned about."

"And that means that the fact that this study shows an increased risk of death associated with GI bleeding says to me that a gastrointestinal problem is simply a marker for someone who is a lot sicker, not an independent factor directly related to the stroke itself," he said. "So, I don't think this finding gives us much useful new information."

More information

For more on post-stroke recovery, visit the National Stroke Association.



SOURCES: Martin O'Donnell, M.D., associate professor, department of medicine, McMaster University, Hamilton, Ontario, Canada; Matthew Fink, M.D., chief, division of stroke and critical care neurology, Weill Cornell Medical College, New York City; Larry B. Goldstein, M.D., director, The Stroke Center at Duke University Medical Center, Durham, N.C.; Aug. 6, 2008, Neurology, online


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Popular Antidepressants Linked to GI Bleeding
2. Bowel prep oral sodium phosphate equal to fasting before capsule endoscopy for obscure GI bleeding
3. Clot-Busting Treatment Improves Bleeding Stroke Outcomes
4. Researchers fine-tune clot-busting treatment for bleeding in brain
5. Noninvasive Procedures Show Promise for Esophageal Bleeding
6. Staff Training Reduces Postpartum Bleeding, Episiotomies
7. Viscosity Enhancers Curb Bleeding Complications
8. Smoking Boosts Bleeding Stroke Risk in Those With High Blood Pressure
9. Alcoholics underestimate the risk of bleeding
10. Anti-Clotting Drug Trial Shortened by Bleeding Problems
11. Research Highlights New Approaches to Management of Blood Clotting and Bleeding Disorders
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
GI Bleeding After Stroke Raises Death Risk
(Date:6/26/2016)... ... 27, 2016 , ... Quality metrics are proliferating in cancer care, and are ... the eye of the beholder, according to experts who offered insights and commentary in ... Managed Care. For the full issue, click here . , For the American ...
(Date:6/26/2016)... ... ... a legally blind and certified personal trainer is helping to develop a weight loss fitness ... to fix the two major problems leading the fitness industry today:, , ... They don’t eliminate all the reasons people quit their exercise program ...
(Date:6/25/2016)... ... ... closing of Bruton Memorial Library on June 21 due to a possible lice infestation, as ... of head lice: the parasite’s ability to live away from a human host, and to ... one in the event that lice have simply gotten out of control. , As lice ...
(Date:6/25/2016)... , ... June 25, 2016 , ... ... and non-athletes recover from injury. Recently, he has implemented orthobiologic procedures as a ... area —Johnson is one of the first doctors to perform the treatment. Orthobiologics ...
(Date:6/24/2016)... ... June 24, 2016 , ... Those who have experienced traumatic events ... turn to unhealthy avenues, such as drug or alcohol abuse, as a coping mechanism. ... tools for healthy coping following a traumatic event. , Trauma sufferers tend to feel ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... and SAN CLEMENTE, Calif. , June 24, 2016 ... mobile pulmonary function testing company, is now able to perform sophisticated ... by ndd Medical Technologies , Inc. Patients ... hospital-based labs.  Thanks to ndd,s EasyOne PRO ® , ARL patients ... get any needed testing done in the comfort of her own ...
(Date:6/24/2016)... -- According to a new market research ... Safety Pen Needles), Needle Length (4mm, 5mm, 6mm, 8mm, ... Purchase (Retail, Non-Retail) - Trends & Global Forecasts to ... for the forecast period of 2016 to 2021. This ... 2021 from USD 1.65 Billion in 2016, growing at ...
(Date:6/24/2016)... Belgium , June 24, 2016 /PRNewswire/ ... announced the appointment of Dr. Edward Futcher ... a Non-Executive Director, effective June 23, 2016.Dr. Futcher ... and Nominations and Governance Committees.  As a non-executive ... provide independent expertise and strategic counsel to VolitionRx ...
Breaking Medicine Technology: