Navigation Links
GEN reports on advances in DNA vaccine delivery and production
Date:9/1/2011

New Rochelle, NY, September 1, 2011Scientists involved in DNA vaccine research are currently focused on two major issues: the creation of effective delivery systems and the development of more efficient biomanufacturing strategies, reports Genetic Engineering & Biotechnology News (GEN). Top investigators in the field recently discussed these and other topics at a conference in San Diego entitled "DNA Vaccines: Building on Clinical Progress and Exploring New Targets," which was sponsored by the International Society of DNA Vaccines and organized by BioConferences International, a Mary Ann Liebert company, according to the September 1 issue of GEN. http://www.genengnews.com/issue/toc/0/

David Weiner, Ph.D., University of Pennsylvania professor and conference chair, noted that despite some early setbacks, DNA vaccine technology has advanced dramatically over the past few years and that therapies currently under evaluation are demonstrating the superb potential of plasmid-based vaccines. He emphasized that a range of novel vaccine methodologies have emerged, including new strategies for getting the plasmids into cells, increasing protein production once they are inside, and modifications of the vaccine proteins that increase their recognition and response by the immune system.

Some of the more promising delivery approaches include transdermal, needle-free patches, devices that transport the plasmids into the skin via air pressure, and electroporation, in which electrical pulses are used to temporarily open the cell membrane, allowing the plasmids easier access to the interior of cells.

On the manufacturing front, Philippe Ledent, Ph.D., process transfer and development manager at Eurogentec Biologics, explained that his company has faced major challenges scaling up the output of both protein and nucleic acid products. For plasmid production Eurogentec turned to fed-batch protocols for
'/>"/>

Contact: John Sterling
jsterling@genengnews.com
914-740-2196
Mary Ann Liebert, Inc./Genetic Engineering News
Source:Eurekalert

0

GOOD

Page: 1 2

Related medicine news :

1. HPV Vaccination Rates Low Among Teen Girls, CDC Reports
2. NNI releases 4 workshop reports from the nanoEHS Series
3. Fast Food Is King of the Neighborhood, Study Reports
4. Vitamin D lower in NFL football players who suffered muscled injuries, study reports
5. Colon Cancer Death Rates Continue to Drop, CDC Reports
6. Patient reports of relatives cancer history often not accurate
7. Mayo Clinic reports new findings on noninvasive test for pancreatic cancer
8. GEN reports on novel noninvasive tests for early cancer detection
9. JAMA study reports on fatty liver disease in children and teens
10. Making temporary changes to brain could speed up learning, study reports
11. U.S. Reports Drop in AIDS-Related Cancers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/19/2013)... Sudden cardiac arrest can strike anyone, even a ... of 5 minutes after cardiac arrest, but the average emergency ... that death is highly probable if an automated external defibrillator ... In response to this dire reality, US Representative Lois Capps ... (H.R. 2308) which would provide support for AED and CPR ...
(Date:6/19/2013)... 19, 2013 Daimer Industries, Inc.®, ... cleaning machines, including reliable truck mount carpet cleaners ... cleaning machine systems , and other advanced cleaning ... for auto detailing professionals. The powerful machine, offering ... Daimer® models, is ideal for maintaining vehicle interiors. ...
(Date:6/19/2013)... Recovery Associates, through its multiple therapeutic ... treatment, helping men and women break free from the ... is a stimulant named for the crystalline structure it ... smoked, but it can also be injected or taken ... labs using common household ingredients and over-the-counter medicine. Crystal ...
(Date:6/19/2013)... Semi Truck Accident Victims Center says, "If you, ... serious accident involving a semi truck, or commercial vehicle in ... we are urging you to call us for our on ... essence, and it really is vital to have a skilled ... investigators in your corner as quickly as possible, and this ...
(Date:6/19/2013)... June 19, 2013 Middle market merger ... across all industries as cash rich buyers seek to ... across industries, all M&A transactions have a good deal ... to verify the history and quality of the target ... , But when due diligence involves a middle market ...
Breaking Medicine News(10 mins):Health News:AED.com Supports Automated External Defibrillator (AED) Legislation in Schools in US and UK 2Health News:Daimer Ships Carpet Cleaners for Car Detailing Steam Cleaner Tasks 2Health News:Daimer Ships Carpet Cleaners for Car Detailing Steam Cleaner Tasks 3Health News:Crystal Meth Addiction Treatment and Crystal Meth Drug Rehab Announced by Recovery Associates 2Health News:The Semi Truck Accident Victims Center Urges Families Of Innocent Victims Of A Semi Truck Accident In Montana, Idaho Or Wyoming To Call Them For An On The Spot Response 2Health News:Newport Board Group, a National Business Advisory Firm of CEOs Cautions Buyers on 5 Questions to Ask Before Acquiring a Technology-Based Middle Market Company 2Health News:Newport Board Group, a National Business Advisory Firm of CEOs Cautions Buyers on 5 Questions to Ask Before Acquiring a Technology-Based Middle Market Company 3
... regular standards then you would see a shrinking pay check, ... to measure up in five areas, including body mass and ... biweekly paycheck if they can't prove to their employer that ... pay $5 extra every two weeks starting in 2008. ...
... of standards among the European Union countries regarding the ... be reduced legal differences between countries that are encouraging ... to people travelling to countries other than their ... or easier to access that over there. According to ...
... places of work is now banned in all of Britain ... bar the habit. ,From 6 am on ... partially enclosed places of work, and most company vehicles have ... still be able to light up outside buildings, in gardens ...
... shifting around body fat to flatten your tummy and ... that ample fat? According to an international study ... ,The study, published online in Nature Medicine, could "revolutionise ... associated with human obesity," the Georgetown University Medical Center ...
... New York on Sunday became the first US city to ... facing an uphill struggle in forcing some eateries to ... majority of New York's 20,000 restaurants, the transition towards healthier ... displayed a degree of reluctance. ,At the heart ...
... superstition and marketing to come together: starry-eyed couples are tying ... as well as the proclamation of the world's seven new ... a magic sacred side and the reputation of bringing luck," ... extra dose of good fortune. ,"Number 7 is ...
Cached Medicine News:Health News:Workers Compelled to Stay in Shape to Avoid Pay Cuts 2Health News:Workers Compelled to Stay in Shape to Avoid Pay Cuts 3Health News:IVF Tourism Marred by Ethical Differences in EU 2Health News:IVF Tourism Marred by Ethical Differences in EU 3Health News:Public Places in England Go Smoke Free 2Health News:Stressed Mice may Hold Clue to How Fat is Stored: Study 2Health News:New York Bans Trans Fats in Restaurants 2Health News:New York Bans Trans Fats in Restaurants 3Health News:A Lucky Number? 7/7/07 2Health News:A Lucky Number? 7/7/07 3
(Date:6/18/2013)... , June 18, 2013  Isis Pharmaceuticals, Inc. (NASDAQ: ... that management will present a general corporate update in conjunction ... on Tuesday, June 25 at 2:10 p.m. Pacific Time in ... for the meeting is as follows: 2:00 p.m. – 2:10 ... as of April 26, 2013) 2:10 p.m. – 3:15 p.m. ...
(Date:6/17/2013)... WASHINGTON , June 17, 2013 ... ) presented additional data today at ENDO 2013, ... demonstrating that tasimelteon can entrain (synchronize) both melatonin ... potential to reset the master body clock and ... Non-24-Hour Disorder (Non-24).  The SET (Safety and Efficacy ...
(Date:6/17/2013)... June 17, 2013 Valeant Pharmaceuticals International, Inc. (NYSE: ... it has filed a preliminary prospectus supplement to its effective ... a similar filing with securities regulatory authorities in each of ... with a public offering of its common shares to raise ... The Company will also grant to the underwriters of the ...
Breaking Medicine Technology:Isis Pharmaceuticals to Present a General Corporate Update at its 2013 Annual Meeting of Stockholders and Open House 2Vanda Presents Data From Phase III Studies that Demonstrate Tasimelteon Restores Daily Cortisol Rhythm In Blind Patients With Non-24-Hour Disorder 2Vanda Presents Data From Phase III Studies that Demonstrate Tasimelteon Restores Daily Cortisol Rhythm In Blind Patients With Non-24-Hour Disorder 3Vanda Presents Data From Phase III Studies that Demonstrate Tasimelteon Restores Daily Cortisol Rhythm In Blind Patients With Non-24-Hour Disorder 4Valeant Pharmaceuticals Announces Public Offering Of Common Shares 2Valeant Pharmaceuticals Announces Public Offering Of Common Shares 3Valeant Pharmaceuticals Announces Public Offering Of Common Shares 4
... collect sample, pipette into testing wells ... FDA 510K cleared multiple drug screen ... both drugs and adulterants. It can ... (5) drugs and can be accompanied ...
... Glucose Monitoring System is a patient insertable short-term ... the DexCom STS Receiver., The DexCom STS Sensor ... the DexCom STS Applicator by the user or ... held in place by an adhesive to the ...
... routine Holter,monitoring, the Burdick Vision ... a,practical, no-nonsense diagnostic tool ideal,for ... This highly accurate and,easy-to-use system ... configurations at a price even ...
... PC-based ECG diagnostics complements transition to ... the incorporation of computer-based technology into ... diagnostic instrumentation have developed. Burdick's Universal ... EMRs making it the ideal choice ...
Medicine Products: