Navigation Links
Future prostate cancer treatments might be guided by math
Date:11/21/2011

COLUMBUS, Ohio Scientists have designed a first draft of a mathematical model that someday could guide treatment decisions for advanced prostate cancer, in part by helping doctors predict how individual patients will respond to therapy based on the biology of their tumors.

These decisions would apply to treatment of cancer that has already spread beyond the prostate gland or that has recurred after initial treatments, such as surgery or radiation. Patients with this more advanced prostate cancer receive a therapy called androgen ablation, which inhibits production of testosterone the culprit that allows a tumor to keep growing.

Though the model's outcomes remain theoretical at this point, the researchers have developed enough of a system to show that their incorporation of some personalized data details about a patient's tumor cell characteristics in particular would give doctors more than they currently have to work with in making decisions about this stage of treatment.

"The model in its current form is proof of the concept that we can capture all of these different outcomes that are observed clinically. But we still need to refine the model with as much individual data as we can obtain," said Harsh Jain, a postdoctoral fellow in Ohio State University's Mathematical Biosciences Institute and lead author of the study.

"We envision that this model would be useful for clinicians who could keep feeding the equations with data about how a patient is responding to therapy, which would offer clues about how his cancer cells are mutating. Once you have an idea about that for the short or medium term, the model could predict the optimal therapy for that patient," Jain said.

The model is described this week in the online early edition of the Proceedings of the National Academy of Sciences. Jain conducted the work with co-authors Steven Clinton, professor, and Arvinder Bhinder, assistant professor-clinical, in Ohio
'/>"/>

Contact: Harsh Jain
hjain@mbi.osu.edu
614-688-0427
Ohio State University
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Preserving lifesaving antibiotics today and for the future
2. Kidney disease care -- whats in store for the future?
3. Undergrads Drinking Patterns May Predict Future Abuse
4. Future climate change may increase asthma attacks in children
5. Everyday clairvoyance: How your brain makes near-future predictions
6. Can oral care for babies prevent future cavities?
7. Coke addicts prefer money in hand to snowy future
8. Abnormal brain ultrasounds in premature infants indicate future risk of psychiatric disorders
9. Concussion baseline important for accurate future assessment in at-risk youth athletes
10. Graft size and patient age may be predictor of need for future ACL revisions
11. Future labor shortfalls of medical professionals predicted due to new demands of health-care reform
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/14/2014)... orphaned by HIV/AIDS in South Africa may provide insight ... behavior issues in other areas of the world, which ... that could lead to successful interventions. , A ... United Nations mentions that due to the HIV/AIDS pandemic, ... African, children are at an increased risk for mental ...
(Date:4/14/2014)... A new study shows that moderate to severe ... risk of stroke, cancer and death. , Results of ... to severe obstructive sleep apnea were four times more ... times more likely to have a stroke (HR = ... (HR = 3.4), and 2.5 times more likely to ...
(Date:4/14/2014)... Dallas study involving serious youth offenders, the answer to one ... seven years: "How long do you think you,ll live?", According ... offending over time., Author Dr. Alex Piquero said the study ... of them offend at very high rates and commit more ... much later in life offend much less., "In a lot ...
(Date:4/14/2014)... with symptoms increasing dramatically during some of the most important ... has found. , Depressive symptoms increased on average by 68 ... young men, who were around 25 years old when they ... their children. The results of the study were published April ... is the first to identify when young fathers are at ...
(Date:4/14/2014)... Lower weight babies and babies who aren,t breastfed ... risk of developing chronic inflammation and related health ... study. , "There were good reasons to hypothesize ... inflammation in adulthood," says Thomas McDade (Northwestern University), ... in the Child & Brain Development program. "It ...
Breaking Medicine News(10 mins):Health News:Researchers identify children with emotional behavior difficulties 2Health News:Researchers identify children with emotional behavior difficulties 3Health News:Study links severe sleep apnea to increased risk of stroke, cancer and death 2Health News:UT Dallas study: Youth who fail to envision future commit more crimes 2Health News:Young dads at high risk of depression, too 2Health News:Low birth weight, less breastfeeding create later health risks 2
... begin meeting the ... on Monday, BOLINGBROOK, Ill., Jan. 11 The ... will officially open its doors on Monday,January 14. After ... and facility reviews from the Illinois,Department of Public Health ...
... to improve results, study says , , FRIDAY, Jan. ... allowing for spontaneous breathing -- the so-called "wake ... mechanical ventilators in intensive care units, a new ... from ventilators and should become common practice, the ...
... of antibodies may block human immunodeficiency virus (HIV)-1 infection ... HIV-1 vaccine. The findings, published by Cell Press in ... antibody induction appears to be a key and necessary ... recent failure of vaccines that stimulated only the T ...
... 11 Welcome to Consumer,Reports Health News ... ConsumerReports.org cover issues pertaining to the efficacy ... natural medicines),mental health, diet and nutrition, food ... products, rates the effectiveness and affordability of,prescription ...
... Health loss caused by type 2 diabetes will more ... most other major causes falls, according to new research ... The research, published in the January 7 edition of ... of disease and injury in Australia from 1993 to ...
... Life Brokerage Partners,announces three new carrier relationships ... With these new additions, Life Brokerage,Partners provides ... of the most,exclusive national insurance carriers and ... agency., New relationships with Midland National, ...
Cached Medicine News:Health News:Adventist Bolingbrook Hospital Opens to the Public 2Health News:Dual Treatment Helps Wean Patients From Ventilators 2Health News:Dual Treatment Helps Wean Patients From Ventilators 3Health News:Uncovering the Achilles' heel of the HIV-1 envelope 2Health News:Consumer Reports Health News 2Health News:Consumer Reports Health News 3Health News:Consumer Reports Health News 4Health News:UQ research predicts type 2 diabetes explosion 2Health News:Life Brokerage Partners Adds New Insurance Carriers 2
(Date:1/15/2014)...  According to Millennium Research Group (MRG), the ... the United States and European ... expand moderately through 2022, with embolization particles representing ... interest in drug-eluting beads (DEBs) and radioembolization spheres ... these markets. The European radioembolization sphere ...
(Date:1/15/2014)... 2014 Reportlinker.com announces that a ... its catalogue: Global ... Systems -- Focus on End Users ... OBJECTIVES A drug delivery system ... in today,s growth in the pharmaceutical industry. ...
(Date:1/14/2014)... , Jan. 14, 2014 ... ), a leading innovator of less invasive, miniaturized ... of advanced heart failure, today announced that it ... will be approximately $53 million, bringing expected full-year ... "Our full-year revenue growth of 87% for 2013 ...
Breaking Medicine Technology:US and European Transcatheter Embolization and Occlusion Device Market to Surpass $1.6 Billion by 2022 2US and European Transcatheter Embolization and Occlusion Device Market to Surpass $1.6 Billion by 2022 3Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 2Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 3Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 4Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 5Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 6Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 7Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 8Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 9Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 10Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 11Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 12Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 13Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 14Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 15Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 16Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 17Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 18HeartWare International Announces Preliminary Fourth Quarter 2013 Revenues 2HeartWare International Announces Preliminary Fourth Quarter 2013 Revenues 3HeartWare International Announces Preliminary Fourth Quarter 2013 Revenues 4
... 2011 Cumberland Pharmaceuticals Inc. (NASDAQ: ... hospital acute care and gastroenterology markets, today announced that ... Company, has been appointed interim Vice President, Finance & ... than 20 years of experience in financial management and ...
... 2011 Spectrum Dynamics announced today it has shipped ... Telluride (CZT) nuclear imaging modules from a new supplier, ... of Redlen,s first integrated CZT nuclear imaging detector product ... high resolution, low dose nuclear medicine cameras. ...
Cached Medicine Technology:Cumberland Pharmaceuticals Appoints Rick S. Greene as Vice President, Finance & Accounting 2Cumberland Pharmaceuticals Appoints Rick S. Greene as Vice President, Finance & Accounting 3Spectrum Dynamics Announces Shipment of Revolutionary D-SPECT™ Cardiac Imaging Systems Using Redlen's New CZT Nuclear Imaging Modules 2Spectrum Dynamics Announces Shipment of Revolutionary D-SPECT™ Cardiac Imaging Systems Using Redlen's New CZT Nuclear Imaging Modules 3
Tennant angled tying forceps with extra delicate smooth jaws, 6 mm tying platform, For 9-0 to 11-0 sutures. Overall length 108 mm....
Catalano curved tying forcep has 6 mm V-grove tying platform. Overall length 100 mm....
Kelman - McPherson angled tying forceps is long with tying platform 10 mm, serrated handle and polished finish....
Suture tying forceps (S&T) is straight, 13.5 cm long, flat handle, 9 mm wide, tip diameter 0.3 mm with tying platform....
Medicine Products: