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Future heat stroke treatment found in dental pulp stem cells
Date:6/5/2014

l deficits and a reduction in oxidative damage to the brain. We suspect that the protective effect of SHED may be related to a decreased inflammatory response, decreased oxidative stress and an increase in hypothalamo-pituitary-adrenocortical axis activity following the heat stroke injury."

There are currently some drawbacks to the experimental therapy, said the researchers. First, there is a limited supply of SHED. Also, SHED transplantation has been associated with cancer and immune rejection.

"Further studies are warranted to determine the precise mechanism or production of SHED-mediated growth factors in our heat stroke model," concluded the researchers.

"This study provides the first step towards a potential therapy for the treatment of heat stroke" said Dr. Shinn-Zong Lin, professor of Neurosurgery and superintendent at the China Medical University Hospital, Beigang, Taiwan and Coeditor-in-chief of Cell Transplantation. "The use of SHED is an intriguing approach which requires further study to elucidate the cellular and secretory factors necessary for benefit."


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Contact: Robert Miranda
cogcomm@aol.com
Cell Transplantation Center of Excellence for Aging and Brain Repair
Source:Eurekalert

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