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Future Astronauts May Be Exposed to Alzheimer's Risk Factor
Date:1/2/2013

WEDNESDAY, Jan. 2 (HealthDay News) -- As NASA sets the stage for increasingly ambitious trips into space, new research highlights a potential hazard for astronauts on long-range missions: Alzheimer's disease.

According to a new animal study published in the Dec. 31 issue of PLoS ONE, the kind of cosmic radiation exposure faced by those on board flights heading toward the far-flung reaches of the galaxy has the potential to speed up the onset of the neurological disease.

"Galactic cosmic radiation poses a significant threat to future astronauts," senior study author Dr. M. Kerry O'Banion, a professor in the University of Rochester Medical Center's department of neurobiology and anatomy, said in a URMC news release.

"The possibility that radiation exposure in space may give rise to health problems such as cancer has long been recognized," he added. "However, this study shows for the first time that exposure to radiation levels equivalent to a mission to Mars could produce cognitive [mental] problems and speed up changes in the brain that are associated with Alzheimer's disease."

The authors point out that here on Earth the planet's magnetic field offers protection from space radiation. Once in deep space, however, all bets are off, with travelers exposed to a never-ending bath of low-level radioactive particles.

For the most, the bombardment is at a low enough level that short-term space travel is not overly concerning, the researchers say

The picture changes, however, when contemplating longer-term trips, such as one to Mars currently planned for 2035 and predicted to take about three years round-trip.

O'Banion, URMC graduate student Jonathan Cherry, the study's first author, and colleagues analyzed the impact on from exposure to high-mass, high-charged iron particles, which move incredibly fast and are able to go right through most solid objects.

Mice exposed to doses deemed comparab
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