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Further Upgrade to 2007 Financial Guidance Based on Strong Revenue Growth; VYVANSE Demand on Track
Date:11/1/2007

2007 2006 2007 2006

$M $M $M $M

________ ________ ________ ________

Income/(loss) from continuing

operations 34.7 87.2 (1,663.9) 169.0

Gain on disposition of

discontinued operations - - - 40.6

________ ________ ________ ________

Numerator for basic and diluted

EPS 34.7 87.2 (1,663.9) 209.6

________ ________ ________ ________

Weighted average number of

shares:

Basic (1) 546.4 504.0 538.9 503.6

Effect of dilutive shares:

Stock options(2) 8.2 4.5 - 4.5

Warrants(2) 0.1 0.6 - 0.6

_______ ________ _______ _______

Diluted 554.7 509.1 538.9 508.7

(1) Excludes shares purchased by the Employee Stock Ownership Trust and presented by the Company as treasury stock.

(2) Calculated using the treasury stock method.

The share equivalents not included in the calculation of the diluted weighted average number of shares are shown below:

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SOURCE Shire plc
Copyright©2007 PR Newswire.
All rights reserved

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