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Further Upgrade to 2007 Financial Guidance Based on Strong Revenue Growth; VYVANSE Demand on Track
Date:11/1/2007

September September September September

30, 30, 30, 30,

2007 2006 2007 2006

$M $M $M $M

________ ________ ________ ________

CASH FLOWS FROM OPERATING

ACTIVITIES:

Net income/(loss) 34.7 87.2 (1,663.9) 209.6

Adjustments to reconcile net

income to net cash provided by

operating activities:

Depreciation and amortization:

- cost of product sales 1.8 1.4 4.4 3.5

- in other costs and expenses 46.3 25.6 107.4 72.3

Amortization of deferred

financing charges 1.4 - 10.6 -

Share based compensation 11.7 9.1 34.1 25.8

In-process R&D charge - - 1,896.0 -

Write down of long-term assets - - - 2.0

Equity in earnings of equity

method investees (0.5) (1.2) (1.7) (5.5)

Gain on sale of product rights (7.1) (63.0) (12.1) (63.0)

Gain on disposition of

discontinued operations - - - (40.6)

Changes in operating assets and

liabilities, net of acquisitions:

Decrease/(increase) in accounts

receivable 38.8 4.8 (64.2) 18.6

Increase in sales deduction

accrual 0.4 4.6 19.3 17.6

(Increase)/decrease in inventory (6.2) 2.4 (46.2) 10.7

(Increase)/decrease in

prepayments and other current

assets (8.6) (28.5) 2.7 (10.4)

Decrease
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SOURCE Shire plc
Copyright©2007 PR Newswire.
All rights reserved

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