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Further Upgrade to 2007 Financial Guidance Based on Strong Revenue Growth; VYVANSE Demand on Track
Date:11/1/2007

________ _______ ________ _______

Income/(loss) from continuing

operations before income taxes and

equity in earnings of equity

method investees 11.0 119.1 (1,621.7) 226.4

Income taxes 23.2 (33.1) (43.9) (62.9)

Equity in earnings of equity

method investees, net of taxes 0.5 1.2 1.7 5.5

________ _______ ________ _______

Income/(loss) from continuing

operations 34.7 87.2 (1,663.9) 169.0

Gain from discontinued operations

(net of income tax expense of

$nil) - - - 40.6

________ _______ ________ ________

Net income/(loss) 34.7 87.2 (1,663.9) 209.6

________ _______ ________ ________

(1) Cost of product sales does not include amortization of intangible assets relating to intellectual property rights acquired, which is included in Depreciation and amortization. Amortization of intangible assets in respect of favorable manufacturing contracts is recorded in cost of product sales.

Unaudited US GAAP results for the three

and nine months to September 30, 2007

Consolidated Statements of Operations (continued)

3 months 3 months 9 months 9 months

to to to to

September September September September

30, 30, 30, 30,

2007 2006 2007 2006

$M $M $M $M


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SOURCE Shire plc
Copyright©2007 PR Newswire.
All rights reserved

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