Navigation Links
Fungus Sheds Light on Development of Human Genders
Date:1/11/2008

Gene findings may explain how the two sexes evolved

FRIDAY, Jan. 11 (HealthDay News) -- One of the oldest known types of fungus seems to contain clues to gender development in humans.

Duke University researchers report on the unusual linkage in the Jan. 10 issue of Nature.

In research with Phycomyces blakesleeanus, the Duke team isolated two versions of a gene that regulates mating. They named these versions sexM (sex minus) and sexP (sex plus). Both encode for a single protein called a high mobility group (HMG)-domain protein that leads to sex differentiation through an unknown process.

This protein is similar to the one encoded by the human Y chromosome, called SRY. When SRY is turned on, a developing fetus develops male characteristics.

The similarity suggests HMG-domain proteins may mark the evolutionary beginnings of sex determination in fungi and humans, said research team leader Dr. Joseph Heitman.

He and his colleagues propose that sexM and sexP were once the same gene that went through a mutation process, which resulted in the evolution of the two separate sex genes. The same process may be responsible for the evolution of the male Y chromosome in humans, Heitman said.

In the next phase of this research, he hopes to identify the sex region in another type of fungus.

"Fungi are good model systems for the evolution of human sexual differentiation because the genetic sequences responsible for sex are smaller versions of chromosomal sex-determining regions in people," Heitman said in a prepared statement.

More information

To learn more about Duke University research, visit its Medical Center and Health System News Office .



-- Robert Preidt



SOURCE: Duke University, news release, Jan. 9, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Photo: Scientists Complete Genome Sequence of Fungus Responsible for Dandruff, Skin Disorders
2. Active compounds found in Ganoderma lucidum fungus with potential to treat prostate cancer
3. New MRI finding sheds light on multiple sclerosis disease progressio
4. Aromatherapy Gift Line Sheds Humorous Light on Modern Therapy
5. New research into plant colors sheds light on antioxidants
6. Yankee Candle Company Sheds Some Light In The Fight Against Breast Cancer
7. Research sheds light on carotid artery stenting risk in elderly
8. New book sheds light on conflicts of politics and science
9. Study Sheds Light on Origins of Sudden Cardiac Death
10. Stanford study highlights cost-effective method of lowering heart disease risks
11. Study shines more light on benefit of vitamin D in fighting cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/20/2017)... , ... February 20, 2017 , ... Researchers at the ... cancer, as well as a marker that may predict response to a particular class ... other types of cancer as well. The new findings were published in Proceedings of ...
(Date:2/20/2017)... ... February 20, 2017 , ... ... announced Biscom Document Router (BDR), the first IoT device from Biscom designed to ... imaging. Biscom will debut BDR at HIMSS17 and will be conducting ...
(Date:2/20/2017)... (PRWEB) , ... February 20, 2017 , ... ReportingMD, a Population Health Software Company, is ... of the company. The new location will triple the size of the previous location ... the town of Sunapee, NH. , “We are excited to expand our footprint ...
(Date:2/20/2017)... ... ... Chuck E. Cheese’s® and Center for Autism and Related Disorders (CARD) recently announced ... throughout New England, New York and New Jersey to provide children with autism spectrum ... Chuck E. Cheese’s in a sensory-friendly environment. , After a successful pilot run ...
(Date:2/19/2017)... Carolina (PRWEB) , ... February 19, 2017 , ... The ... evening undergraduate nursing students, is being led by Amelia Joseph, Ph.D. Joseph was engaged ... initial operations of the nursing department in early 2016. After a nation-wide search, she ...
Breaking Medicine News(10 mins):
(Date:2/20/2017)... Fla. , Feb. 20, 2017 Seal ... its health IT solution for mobile device management and ... 2017 HIMSS Conference and Exhibition in Orlando, ... #4444. Mobile devices have become commonplace in ... comes a new set of concerns, including the disinfection ...
(Date:2/20/2017)... -- Research and Markets has announced the addition of ... Trends - Product (RFID refrigerators and RFID freezers), Application (Diagnostic centers, ... their offering. ... The Global RFID Blood Refrigerator and Freezer Market is poised to ... This industry report analyzes the global markets for ...
(Date:2/20/2017)... FRANCISCO , February 20, 2017 ... expected to reach USD 58.4 billion by 2025, ... Research, Inc. The market is driven by technological ... serve future growth opportunities to the market. For ... with an aim of identifying emerging viruses and ...
Breaking Medicine Technology: