Navigation Links
Fungus Sheds Light on Development of Human Genders
Date:1/11/2008

Gene findings may explain how the two sexes evolved

FRIDAY, Jan. 11 (HealthDay News) -- One of the oldest known types of fungus seems to contain clues to gender development in humans.

Duke University researchers report on the unusual linkage in the Jan. 10 issue of Nature.

In research with Phycomyces blakesleeanus, the Duke team isolated two versions of a gene that regulates mating. They named these versions sexM (sex minus) and sexP (sex plus). Both encode for a single protein called a high mobility group (HMG)-domain protein that leads to sex differentiation through an unknown process.

This protein is similar to the one encoded by the human Y chromosome, called SRY. When SRY is turned on, a developing fetus develops male characteristics.

The similarity suggests HMG-domain proteins may mark the evolutionary beginnings of sex determination in fungi and humans, said research team leader Dr. Joseph Heitman.

He and his colleagues propose that sexM and sexP were once the same gene that went through a mutation process, which resulted in the evolution of the two separate sex genes. The same process may be responsible for the evolution of the male Y chromosome in humans, Heitman said.

In the next phase of this research, he hopes to identify the sex region in another type of fungus.

"Fungi are good model systems for the evolution of human sexual differentiation because the genetic sequences responsible for sex are smaller versions of chromosomal sex-determining regions in people," Heitman said in a prepared statement.

More information

To learn more about Duke University research, visit its Medical Center and Health System News Office .



-- Robert Preidt



SOURCE: Duke University, news release, Jan. 9, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Photo: Scientists Complete Genome Sequence of Fungus Responsible for Dandruff, Skin Disorders
2. Active compounds found in Ganoderma lucidum fungus with potential to treat prostate cancer
3. New MRI finding sheds light on multiple sclerosis disease progressio
4. Aromatherapy Gift Line Sheds Humorous Light on Modern Therapy
5. New research into plant colors sheds light on antioxidants
6. Yankee Candle Company Sheds Some Light In The Fight Against Breast Cancer
7. Research sheds light on carotid artery stenting risk in elderly
8. New book sheds light on conflicts of politics and science
9. Study Sheds Light on Origins of Sudden Cardiac Death
10. Stanford study highlights cost-effective method of lowering heart disease risks
11. Study shines more light on benefit of vitamin D in fighting cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/27/2016)... ... 2016 , ... This campaign aims to provide a path to improved education ... control and change. , As nearly 795,000 Americans suffering from a new or recurrent ... Plus, with an estimated 129,000 of these people dying from stroke, it’s become our ...
(Date:5/27/2016)... ... May 27, 2016 , ... Aimed at nurses and employees ... stories, courtesy of leaders in the nursing and health care industry. It also ... advocates and associations—namely Jones & Bartlett Learning. , Jones & Bartlett Learning is ...
(Date:5/26/2016)... ... May 26, 2016 , ... Despite last week’s media reports ... Yellen and company to wait until March 2017 for an interest rate increase, according ... Robinson College of Business. , “The Federal Open Market Committee (FOMC) dot charts are ...
(Date:5/26/2016)... (PRWEB) , ... May 26, 2016 , ... ... and clinical outcomes, hosted members and suppliers for its inaugural Member Conference at ... on their mission of elevating the operational health of America’s healthcare providers. , ...
(Date:5/26/2016)... Florida (PRWEB) , ... May 26, 2016 , ... ... House® Project offering a new model of care for living and healing, celebrated ... core values: Meaningful Life in a Real Home provided by Empowered Staff. , “This ...
Breaking Medicine News(10 mins):
(Date:5/27/2016)... Amarantus BioScience Holdings, Inc. ... Regenerative Medicine, Neurology and Orphan Diseases, today announced that President & ... upcoming investor conferences: SeeThru Equity MicroCap Conference   ... New York City , NY When: Tuesday, May ... Conference   Where: Grand Hyatt Hotel, 109 East 42 ...
(Date:5/26/2016)... NASHVILLE, Tenn. , May 26, 2016 ... provider of software and analytics, network solutions ... healthcare, today announced it entered into a ... leading provider of outpatient software solutions and ... surgery centers, specialty hospitals and rehabilitation clinics ...
(Date:5/25/2016)... , Germany and GERMANTOWN, ... QIAGEN N.V. (NASDAQ: QGEN ; Frankfurt Prime Standard: ... licensing and co-development agreement with Therawis Diagnostics GmbH to develop ... be to develop and market PITX2 as a marker to ... high-risk breast cancer patients. "We are pleased to ...
Breaking Medicine Technology: