Navigation Links
Funding boost in fight against leukaemia
Date:7/3/2008

University of Manchester researchers have been awarded 1.6 million to study a group of genes identified as playing a key role in leukaemia.

The grant, by Leukaemia Research, will fund work analysing a wide range of cancer-causing genes in the hope of targeting their common mechanisms of action for patient benefit.

"All cancers and leukaemias occur because of mutations in certain genes that stop them functioning properly," said Tony Whetton, Professor of Cancer Cell Biology and research leader.

"Mutations in a group of genes leads to unregulated activity in a group of proteins called tyrosine kinases, which change the actions of other proteins, leading to leukaemia."

The team are using state-of-the-art equipment to discover whether the different leukaemia-associated kinases contribute to the disease in the same way; if they do, it offers the opportunity to develop common therapies to block their actions.

"This would potentially be effective for many different types of leukaemia because the mutated kinase genes we are studying occur in several types of blood and bone marrow cancers," said Professor Whetton, who is Head of the School of Cancer and Imaging Sciences.

"What is also exciting is that there are already drugs that are able to block the actions of kinases. These kinase inhibitor drugs are attracting worldwide attention as a new form of treatment for certain cancers including some leukaemias. We hope to add further leukaemias to this list by understanding more fully what this range of kinases do."

Leukaemia Research currently provides more than 3.6 million in funding to the School of Cancer and Imaging Sciences, complementing ongoing research in other areas of the Manchester Cancer Research Centre (MCRC) alliance between the University and the Christie Trust.

This alliance has had a synergistic effect on cancer research in Manchester by promoting cross-disciplinary collaborations and attracting new funding from government, industry and charities.

Professor Whetton said: "In the past few years we have developed a multidisciplinary research approach, employing the latest cutting-edge technologies to take basic research towards clinical relevance as swiftly as possible.

"In so doing, we have built a research platform that not only enables leukaemia research but cancer research in general on the Christie Hospital NHS Foundation Trust site."


'/>"/>

Contact: Aeron Haworth
aeron.haworth@manchester.ac.uk
44-161-275-8383
University of Manchester
Source:Eurekalert

Related medicine news :

1. U.S. Research Funding Continues to Flatten as U.S. Health Costs Climb - in August 31 Science
2. HHS Announces $75 Million in Supplemental Funding to States for Pandemic Flu Preparedness
3. Launch of second European Cancer Research Funding survey
4. SNM applauds NAS study showing need to restore federal nuclear medicine research funding
5. Center gets national funding for child trauma research
6. Southern Research Institutes Neurodegenerative Disease Drug Discovery Program Receives National Institute of Mental Health Funding
7. Biomoda President Testifies Before New Mexico Legislature Supporting Clinical Funding for Early Lung Cancer
8. CPF Urges Congress to Increase Funding for IPF Research in 2009 Federal Budget
9. Wild American Shrimp Board Agrees To Implement New Self-Funding Measures
10. Women Entrepreneurs Urge Veto Override of SCHIP Funding in the House
11. Coalition Urges Congress to Increase Funding for National Health Service Corps
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/10/2016)... ... February 10, 2016 , ... LaserShip, a regional parcel carrier that ... Bank of Eastern Michigan last Friday in order to aid in the Flint water ... to include a facility located in Clio, only 15 miles away from Flint. , ...
(Date:2/10/2016)... California (PRWEB) , ... February 10, 2016 , ... ... are working together to expand dental health services to the developmentally disabled in ... We Care Dental’s operations to a new facility at 71-949 Highway 111, Suite ...
(Date:2/10/2016)... Middletown, PA (PRWEB) , ... February 10, 2016 , ... ... to offer two webinars in February 2016. Each webinar features a dynamic expert ... therapy to benefit their athletes, patients and facilities. Both events are free to ...
(Date:2/10/2016)... ... February 10, 2016 , ... Intermedix announced ... Emergency Medicine , an emergency medicine professional association, to support the organization's newly ... The American Academy of Emergency Medicine, or AAEM, seeks to empower emergency physicians ...
(Date:2/10/2016)... (PRWEB) , ... February 10, 2016 , ... ... of a master charity program created to assist the local community. Pledging to ... community leaders and nonprofit organizations in the area. Their goal is to bring ...
Breaking Medicine News(10 mins):
(Date:2/11/2016)... DIEGO , Feb. 11, 2016 ... groundbreaking cell-isolation method that opens the door to ... until now have been impossible to isolate with ... to isolate specific tumor types in various stages ... genetic variants of these cells that are clinically ...
(Date:2/11/2016)... Conn. , Feb. 11, 2016  NanoViricides, ... that it has entered into an agreement with ... its nanoviricides® drug candidates in standard animal models ... Romanowski , Research Director. Dr. Romanowski has extensive ... discovery. --> Eric Romanowski , ...
(Date:2/11/2016)... -- North America , Europe ... global market is expected to reach USD 20,190.1 Million by 2020 ... 10.2%. --> North America , ... The global market is expected to reach USD 20,190.1 Million by ... of 10.2%. --> According to a new market research ...
Breaking Medicine Technology: