Navigation Links
Funding boost in fight against leukaemia
Date:7/3/2008

University of Manchester researchers have been awarded 1.6 million to study a group of genes identified as playing a key role in leukaemia.

The grant, by Leukaemia Research, will fund work analysing a wide range of cancer-causing genes in the hope of targeting their common mechanisms of action for patient benefit.

"All cancers and leukaemias occur because of mutations in certain genes that stop them functioning properly," said Tony Whetton, Professor of Cancer Cell Biology and research leader.

"Mutations in a group of genes leads to unregulated activity in a group of proteins called tyrosine kinases, which change the actions of other proteins, leading to leukaemia."

The team are using state-of-the-art equipment to discover whether the different leukaemia-associated kinases contribute to the disease in the same way; if they do, it offers the opportunity to develop common therapies to block their actions.

"This would potentially be effective for many different types of leukaemia because the mutated kinase genes we are studying occur in several types of blood and bone marrow cancers," said Professor Whetton, who is Head of the School of Cancer and Imaging Sciences.

"What is also exciting is that there are already drugs that are able to block the actions of kinases. These kinase inhibitor drugs are attracting worldwide attention as a new form of treatment for certain cancers including some leukaemias. We hope to add further leukaemias to this list by understanding more fully what this range of kinases do."

Leukaemia Research currently provides more than 3.6 million in funding to the School of Cancer and Imaging Sciences, complementing ongoing research in other areas of the Manchester Cancer Research Centre (MCRC) alliance between the University and the Christie Trust.

This alliance has had a synergistic effect on cancer research in Manchester by promoting cross-disciplinary collaborations and attracting new funding from government, industry and charities.

Professor Whetton said: "In the past few years we have developed a multidisciplinary research approach, employing the latest cutting-edge technologies to take basic research towards clinical relevance as swiftly as possible.

"In so doing, we have built a research platform that not only enables leukaemia research but cancer research in general on the Christie Hospital NHS Foundation Trust site."


'/>"/>

Contact: Aeron Haworth
aeron.haworth@manchester.ac.uk
44-161-275-8383
University of Manchester
Source:Eurekalert

Related medicine news :

1. U.S. Research Funding Continues to Flatten as U.S. Health Costs Climb - in August 31 Science
2. HHS Announces $75 Million in Supplemental Funding to States for Pandemic Flu Preparedness
3. Launch of second European Cancer Research Funding survey
4. SNM applauds NAS study showing need to restore federal nuclear medicine research funding
5. Center gets national funding for child trauma research
6. Southern Research Institutes Neurodegenerative Disease Drug Discovery Program Receives National Institute of Mental Health Funding
7. Biomoda President Testifies Before New Mexico Legislature Supporting Clinical Funding for Early Lung Cancer
8. CPF Urges Congress to Increase Funding for IPF Research in 2009 Federal Budget
9. Wild American Shrimp Board Agrees To Implement New Self-Funding Measures
10. Women Entrepreneurs Urge Veto Override of SCHIP Funding in the House
11. Coalition Urges Congress to Increase Funding for National Health Service Corps
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/26/2017)... ... May 26, 2017 , ... Water damage to the flooring of several ... had left education officials with a number of critical issues to address before students ... to be accomplished with little or no disruption to class schedules. Second, the project ...
(Date:5/24/2017)... ... May 24, 2017 , ... In modern research, success depends ... instruments for research and understanding the basic principles that were designed to drive ... innovations in stereo microscopy for brightfield and fluorescence typically used in laboratories working ...
(Date:5/24/2017)... ... 24, 2017 , ... Altec Products, Inc., a leader in enterprise ... one-day technology conference in San Diego, CA. , At nVerge 2017, Altec will ... utilize and enhance their Sage ERP solutions by providing improved visibility and control to ...
(Date:5/24/2017)... ... May 24, 2017 , ... Drs. ... NY, who have now spent 10 years as clinical instructors for the reputable ... College of Dentistry. Through the program, private practitioners receive cutting-edge clinical training and ...
(Date:5/24/2017)... ... , ... Patients who want to receive cosmetic dentistry procedures such as Invisalign® ... for a consultation, with or without a referral. Dr. Bedich enjoys improving the appearance ... , Dr. Bedich offers a variety of cosmetic dentistry services at his practice that ...
Breaking Medicine News(10 mins):
(Date:5/10/2017)... MARLBOROUGH, Mass., May 10, 2017 Hologic, Inc. ... financial results for the fiscal second quarter ended April ... (EPS) of $1.84 increased 666.7% compared to the prior ... business resulted in a significant gain, while non-GAAP diluted ... increased 3.2%, or 3.8% in constant currency terms.  Excluding ...
(Date:5/10/2017)... Md. , May 10, 2017 CSSi, ... solutions for the clinical research industry, is proud to ... www.CSSiEnroll.com . The new website features both enriched content ... user experience and enhances the company,s already well-established position ... industry. "After many months of hard ...
(Date:5/9/2017)... 9, 2017  Semler Scientific, Inc. (OTCQB: SMLR), ... to improve the clinical effectiveness and efficiency of ... first quarter ended March 31, 2017. ... customers to identify when preventive care options are ... like heart attacks or strokes occur," said ...
Breaking Medicine Technology: