Navigation Links
Functional boost for magnetic resonance imaging
Date:1/18/2011

Over the last few years, researchers have used a type of brain scanning, known as functional magnetic resonance imaging fMRI, to help them map changes in blood flow in the brain and to correlate this with thoughts and behavior. A new way to analyze fMRI data, which could improve is reported in the International Journal of Computational Biology and Drug Design.

Scientists have known since the 1890s that changes in blood flow and blood oxygenation in the brain (hemodynamics) are correlated with activity in brain cells, neurons. When a neuron is active it needs more energy from glucose and this demand increases blood flow to the regions of the brain where there is more neural activity. This leads to local changes in the relative concentration of oxyhemoglobin and deoxyhemoglobin and changes in local cerebral blood volume and in local cerebral blood flow, which researchers have been measuring using fMRI since the early 1990s. Since then, brain mapping using this relatively non-invasive technique, which also avoids exposure to ionizing radiation has become more and more widely used.

Researchers have used fMRI to study brain development and function, to diagnose problems following injury and to predict when a person might be fit enough to return to work, as an alternative to lie detectors, to allegedly peer into a person's dreams, and even to communicate with patients in a vegetative state. Many of the experiments that have received attention in the news media are controversial in that interpreting images of changing blood flow in the brain is only a proxy of actual activity Moreover, extrapolating those proxy images to thoughts and behavior involves a not in significant extrapolation.

Now, Chuan Li and Qi Hao of the Department of Electrical and Computer Engineering, at The University of Alabama, Tuscaloosa, have developed a more robust, three-stage approach to fMRI that could improve the detection of neural activity considerably and allow researchers to make more precise interpretations of fMRI data.

The team explains that there are three stages to their approach: prediction, modeling and inference. Prediction involves identifying regions of interest associated with an extraordinary amount of neural activity through Temporal Clustering Analysis (TCA). Modeling involves categorizing the fMRI signals related to neural activity into event prototypes through Linear Predictive Coding (LPC). Finally, inference is the determination of the types of neural activity taking place in terms of activation, deactivation and normality using a type of statistical analysis known as Bayesian inference.

Their approach side-steps to some extent the problems inherent in current approaches to fMRI, namely low signal-to-noise ratio, high data volumes, differences between patients or subjects and artifacts caused by the movement of the person being scanned. Their approach allows them to turn large amounts of often noisy data into discrete sequences of neural activity events. The team has demonstrated how well their approach works by analyzing data from fMRI scans on volunteers involved in the simple activities of drinking a glass of water or a glass of glucose solution.

"Our expertise is in signal processing and machine learning. Our research goal is to develop a set of powerful signal processing tools for fMRI researchers," says Hao.


'/>"/>

Contact: Qi Hao
qh@eng.ua.edu
205-348-2618
Inderscience Publishers
Source:Eurekalert

Related medicine news :

1. New Liquid Functional Nutrition Products: EYL Beverages Announces Debut of DeCOMPRESS™ and Debug™ Beverages at Natural Products EXPO West
2. Greenway Awarded U.S. Patent For EHR Functionality and Workflow
3. Multifunctional nanoparticle enables new type of biological imaging
4. Acid reflux, functional dyspepsia have significant impact on disordered sleep
5. Study shows volunteering benefits those with functional limitations
6. Global Nutrition Firm Takes Dose of SonicWALL to Boost Network Health
7. Aspirin May Boost Breast Cancer Survival
8. A midday nap markedly boosts the brains learning capacity
9. CustomerCentric Selling Helps BCC Software Dramatically Boost Sales Performance and Produce Record Results
10. Dry Weather Boosts Odds of Flu Outbreaks
11. Fitness Boosts Brain Power in Multiple Sclerosis Patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/3/2016)... ... ... Park Cities Pet Sitter has openings for both full-time and part-time pet ... 75220, 75225, 75229, 75230, 75231 and 75235 zip codes. These zip codes are ... Park Cities areas of the Metroplex. Candidates must love animals, have attention to ...
(Date:5/3/2016)... ... May 03, 2016 , ... ... announces Benefits Alliance Insurance Services as the latest addition to its elite stable ... comprised of Partners Wayne Blasman, David Styles, and Paul Vincent. The Firm is ...
(Date:5/3/2016)... ... 2016 , ... For the sixth consecutive year, Crawford Technologies ... companies in the annual Branham300 listing. For 23 years, the Branhan300 has highlighted ... revenue. , “We are honored to be on the Branham300 list once ...
(Date:5/3/2016)... ... , ... Dr. Poneh Ghasri, cosmetic dentist in West Hollywood , is ... patients. Cosmetic dentistry allows patients to improve the aesthetics of their smiles. These treatments ... or more serious cosmetic flaws. These specials allow patients to achieve their dream smiles ...
(Date:5/3/2016)... City, NJ (PRWEB) , ... May 03, 2016 ... ... announced the general availability of the latest release of DocAve 6 Service ... release, AvePoint helps organizations migrate to SharePoint 2016 and take advantage of the ...
Breaking Medicine News(10 mins):
(Date:5/3/2016)... from Sino-German High-Tech Fund to further expand product development, strengthen its disease modeling capabilities and increase market presence. ... ... ... ... Sino-German High-Tech ...
(Date:5/3/2016)... , May 3, 2016   BIOTRONIK , ... today announced Food and Drug Administration (FDA) approval ... that provides heart failure patients with access to ... also have remote monitoring with daily automatic transmission ... heart rate in response to physiological demands. ...
(Date:5/3/2016)... , May 3, 2016   Diplomat Pharmacy, Inc. (NYSE: DPLO) announced today that it is ... a video of two patients who tell their personal story and encourage those at risk ... Meet Jacque: Hepatitis C ... ... Diplomat Specialty Pharmacy (PRNewsFoto/Diplomat Pharmacy, Inc.) ...
Breaking Medicine Technology: