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Frost & Sullivan Recognizes Singulex for Erenna(R) Immunoassay System
Date:6/15/2009

building on its diagnostic business by offering our proprietary Molecular Cardiac Troponin-I (cTnI) testing services in our CLIA laboratory for early detection and monitoring of cardiovascular disease risk."

The Erenna Immunoassay System is a simple, easy-to-use bench-top analytical instrument with ready-made reagents that provides high-resolution results directly from biological specimens such as serum or plasma. The system includes data management software and can be integrated into an existing clinical laboratory workflow. The system can also be integrated with automated robotic handling units to provide high throughput capabilities for biomarker quantification and validation.

"The technology behind the Erenna system comprises two important stages: a modified microparticle (MP)-based sandwich immunoassay followed by a single molecule counting technology," explains Frost & Sullivan Healthcare Industry Analyst Pramodh Ishwarakrishnan. "The system combines a 384-well plate format for sample analysis, capillary flow, laser-induced fluorescence, and a highly sensitive detection optics module."

Increased sensitivity and precision are essential for robust measurement of disease biomarkers, and the Erenna system enables high resolution monitoring by accurately quantifying minute changes in biomarker concentration in patient specimens over time. The Erenna system measures each fluorescent-labeled detection antibody as a unique digital event separate from the background fluorescent signal, unlike conventional analog systems that count the total light together with background. Thus, the system offers enhanced specificity, sensitivity, and precision by 1 to 2 logs over existing plate-based methods.

Each year, Frost & Sullivan presents this award to the company (or individual) that has carried out new research that has resulted in innovation(s) that have or are expected to bring significant contributi
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SOURCE Frost & Sullivan
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