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Frost & Sullivan Lauds Pioneer Surgical Technology for Development of Tissue Scaffold E-Matrix
Date:3/19/2009

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The E-Matrix(TM) monomer contains exposed polar binding sites which can react with host cells thus leading to the growth and repair of tissues. The E-Matrix(TM) bio-scaffold provides an open structure that makes these exposed molecular sequences normally obscured in the ECM available to host cells. The bio-scaffold is tissue specific and provides a healing response based on the tissue in which it is used. A key feature of Pioneer Surgical's solution is that its applications span a variety of therapeutic areas ranging from orthopedic and spine to dermal and dental tissue repair.

The E-Matrix's(TM) primary competitive advantage over other existing scaffolds is its ability to provide excellent handling properties based on the products that it is used with and its ability to provide a superior scaffold for growth and differentiation of cells. It has also been used in combination with nanocrystalline hydroxyapatite to provide an innovative osteopromotive bone graft and also with human demineralized bone matrix (DBM) to improve the healing response of DBM containing bone graft products.

"With the use of the E-Matrix(TM) bio-scaffold, problems associated with the consistency of biological response may be eliminated. The results of trials conducted using the scaffold have yielded promising results," notes Ishwarakrishnan. "Since the bio-scaffold re-engineers natural ECM with an open structure to provide newly exposed molecular sequences to cells, it could herald the use of a new approach for the development of future scaffolds for tissue engineering."

Pioneer Surgical has a fast paced innovation oriented culture where employee's creativity is encouraged. The caliber of its people and the ideas they have brought have helped the company foster excellence in innovation. For developing a unique scaffold which, with its potential for several surgical applications, could steer tissue engineering research, Pioneer
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