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Frost & Sullivan Lauds Pioneer Surgical Technology for Development of Tissue Scaffold E-Matrix
Date:3/19/2009

MOUNTAIN VIEW, Calif., March 19 /PRNewswire/ -- Based on its recent analysis of the field of orthopedic tissue engineering, Frost & Sullivan recognizes Pioneer Surgical Technology, Inc. with the 2009 North American Technology Innovation of the Year Award for its development of the E-Matrix(TM) tissue scaffold for use in orthopedic and spine tissue engineering. The uniqueness of the scaffold rests with the fact that it provides a suitable matrix for cell growth and differentiation in addition to being tissue-specific.

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Tissue engineering has largely been used to repair and build human tissue and organs with the main focus being on bones and cartilage. One of the key areas in tissue engineering is the development of biodegradable scaffolds for the growth of cells and tissues. Several synthetic (polyglycolic acid) and natural materials (hyaluronic acid, collagen) have been used to make scaffolds.

"Current generation biological scaffolds do not provide tissue promotion besides using inappropriate matrix materials, and having decreased strength and porosity of scaffolds," says Frost & Sullivan Research Analyst Nandini Ishwarakrishnan. "Overcoming such limitations, Pioneer Surgical's biological scaffold is based on extracellular matrix (ECM) material and is targeted to orthopedic and wound healing applications."

The E-Matrix(TM) structure is derived from porcine collagen and is widely used in promoting dermal healing and bone repair. The structure combines a high-molecular weight protein with a high-molecular weight carbohydrate, mimicking the open ECM structure of an early mesenchymal tissue. Single stranded molecules are produced by unraveling triple helical collagen structures and these are further stabilized by adding large carbohydrate molecules.'/>"/>

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