Navigation Links
From the dust -- mixing stem cells with clay to regenerate human tissue
Date:5/2/2014

nth of a millimetre, could overcome two challenges in the development of stem-cell based regenerative therapies.

The first challenge to deliver and hold stem cells at the right location in the body would be met by the ability of clay to self-organise into gels via the electrostatic interactions of the particles with each other. Cells mixed with a low concentration of clay particles gelled in water, can be injected into the body and held in the right place by the gel, eliminating, in many situations, the need for surgery.

Clay particles can also interact with large structural molecules (polymers) which are frequently used in the development of scaffolds, which stem cells grow on. These interactions can greatly improve the scaffold's strength and could be applied to preserve their stability at the site of injury until regeneration is complete.

While several gels and scaffold materials have been designed to deliver and hold stem cells at the site of regeneration, the ability of clay nanoparticles to overcome a second critical hurdle facing stem-cell therapy is what makes them especially exciting.

Dr Dawson says: "The carefully controlled provision of key biological signalling molecules is essential to directing the activity of stem-cells. However, conventional injectable gel materials are often poor at retaining these biological signals at the site of injury they can hold and deliver cells, but the molecules that stimulate the cells diffuse away when placed in the body. The ability of clay nanoparticles to bind biological molecules presents a unique opportunity to control the local environment at a site of injury or disease to stimulate and control stem-cell driven repair. This is something we are very excited about."


'/>"/>

Contact: Becky Attwood
r.attwood@soton.ac.uk
44-023-805-92116
University of Southampton
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Water-based engine propels tumor cells through tight spaces in the body
2. UNC researchers discover master regulator role for little-known protein in cancer cells
3. Brain tumor cells penetrated by tiny, degradable particles carrying genetic instructions
4. A civil war inside our cells: Scientists show how our bodies fight off jumping genes
5. Scientists find way to target cells resistant to chemo
6. Boring cells could hold the key to heart disease
7. Following a proteins travel inside cells is key to improving patient monitoring, drug development
8. Dustman protein helps bin cancer cells
9. Efficient analysis of small quantity of cells improves chances to understand disease
10. New human trial shows stem cells are effective for failing hearts
11. Plasma tool for destroying cancer cells
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
From the dust -- mixing stem cells with clay to regenerate human tissue
(Date:9/22/2014)... September 22, 2014 The Spa Standard, ... to lead the start-up in developing content and courses ... to the company over 15 years of experience in ... resort spa management with companies including Orient Express Hotels ... the role of educator, Jenny gained extensive industry insight ...
(Date:9/22/2014)... the proverbial needle in the cancer antigen haystack, according ... of Experimental Medicine . , As cancer ... creates new versions of proteins, some of which are ... cells, prompting the cells to attack and eliminate the ... of the mutations in a patient,s cancer and to ...
(Date:9/22/2014)... 2014--Women who are about to be released from prison ... if they are to successfully reintegrate into their communities ... study. , Almost half of all female prisoners are ... and most have multiple prison terms, mainly for drug-related ... Michael,s Hospital, conducted one-on-one interviews with women who were ...
(Date:9/22/2014)... BCC Research ( http://www.bccresearch.com ) reveals ... GLOBAL MARKETS, the global market for autoimmune disease ... billion by 2019, with a five-year compound annual ... holds the highest market potential due to an ... western lifestyles. , In recent decades, autoimmune ...
(Date:9/22/2014)... on Trauma, patients with severe injuries should be treated ... centers have the resources to provide the best care ... major trauma patients in 2010 actually received their treatment ... a new study from the Center for Pediatric Trauma ... at Nationwide Children,s Hospital. Those patients are "undertriaged." The ...
Breaking Medicine News(10 mins):Health News:The Spa Standard Appoints Vice-President of Content and Course Development 2Health News:Involving female offenders in release planning can increase reintegration success 2Health News:Global Market for Autoimmune Disease Diagnostics to Reach Nearly $13.1 Billion in 2019; Southern Asia Holds the Highest Potential 2Health News:Global Market for Autoimmune Disease Diagnostics to Reach Nearly $13.1 Billion in 2019; Southern Asia Holds the Highest Potential 3Health News:New study finds 34 percent of severely injured patients undertriaged in the United States 2Health News:New study finds 34 percent of severely injured patients undertriaged in the United States 3
... Health plans today proposed guaranteed coverage for people with pre-existing ... , , Under the ... market would be required to offer coverage to all applicants ... individuals were required to maintain health insurance. , ...
... Inc. (NYSE: PRX ) today announced that it ... the U.S. to market budesonide,inhalation suspension, which is a generic ... asthma. Par began,shipping 0.25 mg/2 ml and 0.5 mg/2 ... Full-year US sales for PULMICORT(R) in 2007 totalled ...
... human trial , , WEDNESDAY, Nov. 19 (HealthDay News) -- ... patients may not slow the disease, new research suggests. ... spurred by promising animal research that had suggested that ... on the brain. , However, "the study suggests that ...
... , TORONTO, Nov. 19 /PRNewswire-FirstCall/ - Bradmer ... and commercialization of cancer therapies, announced today that it ... data from Neuradiab(TM) at the Society for Neuro-Oncology,s (SNO) ... from two previously conducted Phase II trials, is titled ...
... medicine community: "Are Your Cells Free?" Learn more about InVitria at TERMIS ... ... Collins, CO (PRWEB) November 19, 2008 -- Stem cell culture researchers ... Tissue Engineering Meeting TERMIS in San Diego on Dec. 7-10. ...
... anniversary of the adoption of the United Nations Convention on the ... ARLINGTON, Va., Nov. 19 The Child Welfare League of America ... Rights of the Child (CRC), the American Psychological Association, and the ... Children,s Health Issues and The Convention on the Rights of the ...
Cached Medicine News:Health News:Health Plans Propose Guaranteed Coverage for Pre-Existing Conditions and Individual Coverage Mandate 2Health News:Health Plans Propose Guaranteed Coverage for Pre-Existing Conditions and Individual Coverage Mandate 3Health News:Par Pharmaceutical Begins Shipment of Budesonide Inhalation Suspension Immediately 2Health News:Growth Hormone Boost May Not Slow Alzheimer's 2Health News:Growth Hormone Boost May Not Slow Alzheimer's 3Health News:Bradmer to present poster on progression free survival and overall survival data from Neuradiab(TM) Phase II trials at Society for Neuro-Oncology Meeting 2Health News:Bradmer to present poster on progression free survival and overall survival data from Neuradiab(TM) Phase II trials at Society for Neuro-Oncology Meeting 3Health News:Bradmer to present poster on progression free survival and overall survival data from Neuradiab(TM) Phase II trials at Society for Neuro-Oncology Meeting 4Health News:InVitria to Launch "BE FREE" Promotion at TERMIS '08 in San Diego 2Health News:Linda Spears, CWLA Vice President of Policy Will Speak at Senate Briefing 2
(Date:9/22/2014)... DALLAS and NEW YORK ... PHARMACEUTICALS, INC. (OTCBB: ACCP), has signed an exclusive, ... for the development and commercialization of its proprietary ... new corporate management team and its intention to ... Biopharmaceuticals, Inc.™, and its plans to pursue a ...
(Date:9/22/2014)... Sept. 22, 2014 Research and Markets ... Chinese Diclofenac Industry Report 2014" report to their ... Industry Report 2014 is a professional and in-depth study ... with a focus on the Chinese situation. ... including definitions, classifications, applications and industry chain structure. The ...
(Date:9/20/2014)... 20, 2014 /CNW/ - The issue: Mylan Pharmaceuticals ULC Canada, ... of its Mylan-Nitro Spray 0.4 mg/metered dose due to the ... pump component. A missing "dip tube" could ... the patient. This defect may lead patients to believe they ... to access it. Not receiving nitroglycerin could place them at ...
Breaking Medicine Technology:Access Pharmaceuticals Announces Exclusive Global Plasma Therapeutics License, New Management And New Corporate Name 2Access Pharmaceuticals Announces Exclusive Global Plasma Therapeutics License, New Management And New Corporate Name 3Access Pharmaceuticals Announces Exclusive Global Plasma Therapeutics License, New Management And New Corporate Name 4Access Pharmaceuticals Announces Exclusive Global Plasma Therapeutics License, New Management And New Corporate Name 5Access Pharmaceuticals Announces Exclusive Global Plasma Therapeutics License, New Management And New Corporate Name 6Global and Chinese Diclofenac Industry Report 2014 2Advisory - Mylan Pharmaceuticals recalling nitroglycerin spray due to defective pump 2
... November 2005. Specifications, including colors, subject to ... lb (2.3 kg), FreeStyle by AirSep is ... for those patients who know no boundaries. ... FreeStyle captures the heart of what it ...
... is AirSep Corporations most economical line of ... lpm of therapeutic oxygen in home, hospital, ... of units in daily use throughout the ... known for high performance, easy maintenance, and ...
... to 10 LPM of oxygen reducing the delivery ... M10 is engineered to reduce the cost of ... fewer parts than any other concentrator on the ... you to reduce expenditure on accessories and unnecessary ...
... conserver, it's important to have a choice that ... name synonymous with innovative excellence, offers two great ... automatic and value packed conservers., ,With its ... used 8 hours a day for 3 to ...
Medicine Products: