Navigation Links
Frequent heartburn may predict cancers of the throat and vocal cord
Date:5/23/2013

PHILADELPHIA Frequent heartburn was positively associated with cancers of the throat and vocal cord among nonsmokers and nondrinkers, and the use of antacids, but not prescription medications, had a protective effect, according to data published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

"Previous studies examining gastric reflux and cancers of the head and neck have generated mixed results," said Scott M. Langevin, Ph.D., postdoctoral research fellow at Brown University in Providence, R.I. "Most of those studies had either few numbers of cases or they were not adjusted for confounding factors. Ours is a large, population-based study with robust parameters that strongly suggests gastric reflux, which causes frequent heartburn, is an independent risk factor for cancers of the pharynx (throat) and larynx (vocal cord)."

Langevin and his colleagues identified 631 patients from a large group of individuals enrolled in a population-based, case-control study in the greater Boston area. Of the 631 participants, 468 had throat cancer and 163 had cancers of the vocal cord. An additional 1,234 individuals matched for age and gender with no prior history of cancer were recruited using town records to serve as controls for the study.

All participants completed a questionnaire on their history of heartburn, smoking and drinking habits, family history of cancer and sociodemographic information. Because some head and neck cancers are caused by infection with human papillomavirus 16 (HPV 16), the researchers tested for the presence of antigens to HPV 16 viral proteins in the blood of all participants.

Langevin and his colleagues found that among participants who were neither heavy smokers nor heavy drinkers, a history of frequent heartburn was linked to a 78 percent increased risk for cancers of the throat and vocal cord. They also found that among those who had frequent heartburn, taking antacids, but not prescription medications or home remedies, had a protective effect, with a 41 percent reduced risk for cancers of the throat and vocal cord. The protective effect of antacids was consistent, irrespective of the participants' smoking or drinking status, HPV 16 status or tumor site.

"Additional studies are needed to validate the chemopreventive effects of antacids among patients with frequent heartburn," said Langevin. "The identification of gastric reflux as a risk factor for throat and vocal cord cancers, however, may have implications in terms of risk stratification and identification of high-risk patients."


'/>"/>

Contact: Jeremy Moore
jeremy.moore@aacr.org
215-446-7109
American Association for Cancer Research
Source:Eurekalert

Related medicine news :

1. UC Davis study finds stray-bullet shootings frequently harm women and children
2. HPV testing in HIV-positive women may help reduce frequent cervical cancer screening
3. Men with large waists face an increased risk of frequent urination
4. Frequent MRI Scanner Exposure Might Affect Memory: Study
5. Homelessness, Frequent Moves Affect How Kids Do in School
6. Breast Cancer Message Board study finds frequent discussion of drug side effects, stopping therapy
7. Frequently prescribed drug used in concerning ways with harmful side effects
8. Survey shows medical students have frequent interactions with pharmaceutical companies
9. Smaller Aortic Aneurysms May Require Less Frequent Monitoring
10. Maternal obesity increases the risk of frequent wheezing in offspring
11. Frequent Moves Take Toll on Poor Kids, Study Suggests
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/9/2016)... (PRWEB) , ... December 09, 2016 , ... ... Ball at The Pierre Hotel in New York, NY, on December 3rd, to ... dignitaries and physicians attended the annual event, which raised over $1 million - ...
(Date:12/8/2016)... WV (PRWEB) , ... December 08, 2016 , ... ... it will become Quality Insights beginning January 1, 2017. The name change ... its commitment to measuring and improving health care quality. , “We are very ...
(Date:12/8/2016)... ... 08, 2016 , ... ZyDoc , a New York-based ... Data Capture Methods for Input to Electronic Health Records: A Comparative Usability Study” ... comparative usability study demonstrate that a dictation-based method (“NLP Entry”) using ZyDoc’s MediSapien™ ...
(Date:12/8/2016)... ... 2016 , ... With the increasing demand for dental implants, the National Association ... to inform dentists and patients about the safety issues related to dental restorations. According ... the U.S. is projected to reach $6.4 billion in 2018 with more than 30 ...
(Date:12/8/2016)... ... December 08, 2016 , ... ... continuity to its innovative Unified Instance Manager architecture, meeting the needs of ... new version optimizes the unattended auto-dialing system without agents, Presence Robodialer, provides ...
Breaking Medicine News(10 mins):
(Date:12/8/2016)... VIEW, Calif. , Dec. 8, 2016 IRIDEX ... intends to offer newly issued shares of common stock, $0.01 ... pursuant to an underwritten public offering.  The final terms of ... the time of pricing, and there can be no assurance ... IRIDEX expects to use the net proceeds it ...
(Date:12/8/2016)... Australia Glaucoma Surgery Devices Market Outlook ... "Australia Glaucoma Surgery Devices Market Outlook to 2022", ... Surgery Devices market. The report provides value, in ... average prices (USD) within market segement - Glaucoma ... shares and distribution shares data for each of ...
(Date:12/8/2016)... -- The global biosurgery market is expected to grow at ... 2016 to 2021. The market is poised to reach ... in 2016. The market is primarily driven by rising ... and spinal problems, increasing clearance of biosurgery products by ... management. In this report, the biosurgery market ...
Breaking Medicine Technology: