Navigation Links
Freezing breast tumors helps stop cancer’s spread in mice, U-M study finds
Date:3/3/2010

ANN ARBOR, Mich. Freezing a cancer kills it in its place, and also appears to generate an immune response that helps stop the cancer's spread, leading to improved survival rates over surgery, according to a new study in mice from researchers at the University of Michigan Comprehensive Cancer Center.

Researchers looked at two different cryoablation techniques, which both involve applying a cold probe to a tumor to freeze it. The study was done in mice with breast cancer. One method involves freezing the tumor rapidly, in about 30 seconds; the other freezes the tumor slowly, taking a few minutes. Results from the cryoablation were compared to results from mice whose tumors were removed with surgery.

Both cryoablation techniques successfully killed the breast tumor. The mice treated with the rapid freeze had fewer tumors that spread to the lungs and improved survival compared to mice treated with surgery alone or mice treated with the slower freezing technique. The study showed that the benefit from the rapid freezing is likely due to changes in the immune system that help to kill the tumor. Freezing with the slower technique appeared to make the immune system not as able to kill the tumor.

The study appears online in Annals of Surgical Oncology. Based on these results from mice, researchers are now conducting a clinical trial using cryoablation in patients with breast cancer. In this trial, researchers use the rapid freezing technique.

"Cryoablation has strong potential as a treatment for breast cancer. Not only does it appear effective in treating the primary tumor with little cosmetic concerns, but it also may stimulate an immune response capable of eradicating any cells that have traveled throughout the body, reducing both local and distant recurrence, similar to giving a breast cancer vaccine," says lead study author Michael Sabel, M.D., associate professor of surgery at the U-M Medical School.

"What we
'/>"/>

Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System
Source:Eurekalert

Page: 1 2

Related medicine news :

1. At last! A Remarkable Breakthrough for Parkinson's Disease Freezing: The GaitAid Virtual Walker
2. Advanced Bag Design for Cryopreservation: The New CryoMACS(R) Freezing Bag
3. Freezing Kidney Cancers Shows Promise
4. Freezing Ovaries Preserves Fertility, Scientists Report
5. Tissue-Freezing Technique Effective Against Prostate Cancer
6. Pacific Fertility Center Announces Breakthrough in Egg Freezing Technology
7. Common osteoporosis drugs are associated with a decrease in risk of breast cancer
8. Breast Cancer Charity Website Offers Breast Cancer Profiler Tool
9. PINC trial launched to test new treatment for pre-invasive breast cancer
10. How estrogen feeds breast tumors
11. A primer on aspirating breast lumps
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/4/2015)... Hanover, MA (PRWEB) , ... August 04, 2015 , ... ... Brain Aneurysm Awareness on Sunday, September 20th at Oneida Shores Park in Brewerton, ... after suffering from a ruptured brain aneurysm at the young age of 59. Her ...
(Date:8/4/2015)... ... August 04, 2015 , ... IN AMERICA and the ... treating depression. Depression affects millions of Americans every single year. To help people ... enlighten viewers with the latest segment produced with the assistance of several top ...
(Date:8/4/2015)... DC (PRWEB) , ... August 04, 2015 , ... Following ... two new videos: The Benefits of Cath Lab Accreditation in an Academic Setting, and ... in an Academic Setting , taped during the 2015 Society for Cardiovascular Angiography ...
(Date:8/4/2015)... ... August 04, 2015 , ... ... make the Isabel Symptom Checker available to all users of the KHIN personal ... check their symptoms in an easy, intuitive method, provides access to material on ...
(Date:8/3/2015)... ... 04, 2015 , ... While the pace of the economic recovery since the 2008 has been ... a growth trajectory for the last six years. Unemployment has dropped from a 2009 high ... 3.5 percent growth rate in 2014, the U.S. stock market is at an all time ...
Breaking Medicine News(10 mins):Health News:4th Annual Doris A. Connor Memorial Event for Brain Aneurysm Awareness to be Held in Brewerton, NY with Proceeds Benefitting Renowned Brain Aneurysm Foundation 2Health News:4th Annual Doris A. Connor Memorial Event for Brain Aneurysm Awareness to be Held in Brewerton, NY with Proceeds Benefitting Renowned Brain Aneurysm Foundation 3Health News:Accreditation for Cardiovascular Excellence (ACE) Clients Explain Benefits of ACE Accreditation 2Health News:Accreditation for Cardiovascular Excellence (ACE) Clients Explain Benefits of ACE Accreditation 3Health News:Isabel Healthcare Partners with the Kansas Health Information Network, Inc. to Deploy Isabel Symptom Checker within the MyKSHealth eRecord Personal Health Record 2Health News:Isabel Healthcare Partners with the Kansas Health Information Network, Inc. to Deploy Isabel Symptom Checker within the MyKSHealth eRecord Personal Health Record 3Health News:Newport Board group, an Advisory Firm Serving the Middle Market, Cautions Businesses on How to Survive the Coming Recession 2Health News:Newport Board group, an Advisory Firm Serving the Middle Market, Cautions Businesses on How to Survive the Coming Recession 3Health News:Newport Board group, an Advisory Firm Serving the Middle Market, Cautions Businesses on How to Survive the Coming Recession 4
... -- A University of Michigan Health System laboratory study reveals ... could lead to a new treatment for those with sickle ... in this week,s early edition of the Proceedings of ... preventing the painful episodes and organ damage that are common ...
... Gordon HealthDay Reporter , TUESDAY, Nov. 1 (HealthDay ... their risk of developing cancer compared to the general population. ... cancer, according to new research. In any ... transplant is just 0.7 percent. And experts say the benefits ...
... Gardner HealthDay Reporter , TUESDAY, Nov. 1 ... disorder don,t appear to raise the risk of heart ... adults, new research shows. And if any ... Concerta does exist, the danger in absolute numbers would ...
... equation that is difficult to solve for most people, but ... transport can be an almost insurmountable task. A newly launched ... now enlisting the help of the senior citizens themselves to ... hoped that the results will lead to better urban planning. ...
... -- Women undergoing angioplasty, a procedure to unblock a clogged ... to new research. However, the study also shows ... an angioplasty than male patients. In conducting the study, ... Interventions , researchers analyzed information on almost 4,800 women and ...
... from Rhode Island Hospital examined how the perception of ... Through a web survey with embedded interventions, the researchers ... indicators of patient satisfaction, while staff reported changing or ... paper was published in the European Journal of ...
Cached Medicine News:Health News:Researchers reveal potential treatment for sickle cell disease 2Health News:Cancer Risk Doubles After Organ Transplant, Study Finds 2Health News:Cancer Risk Doubles After Organ Transplant, Study Finds 3Health News:Little Evidence of Heart Risks From ADHD Meds 2Health News:Little Evidence of Heart Risks From ADHD Meds 3Health News:Little Evidence of Heart Risks From ADHD Meds 4Health News:Senior citizens as co-researchers to improve urban planning 2Health News:Women No More Likely to Die After Angioplasty 2Health News:How staff perceptions of their roles impact patients experience in the emergency department 2Health News:How staff perceptions of their roles impact patients experience in the emergency department 3
(Date:8/3/2015)... Calif., Aug. 3, 2015  DURECT Corporation (Nasdaq: DRRX ... 2015.  Total revenues were $4.4 million and net loss was ... as compared to total revenues of $4.6 million and net ... 30, 2014.At June 30, 2015, we had cash and investments ... million at December 31, 2014.  At June 30, 2015, we ...
(Date:8/3/2015)... -- ReportsnReports.com adds Global Medical Simulation ... as well as Global Medical Simulation Market 2015-2019 ... of its library. Complete 2015 report ... across 164 pages, talking about 7 major companies ... now available at http://www.reportsnreports.com/reports/407046-global-medical-simulation-industry-report-2015.html . ...
(Date:8/3/2015)... RARITAN, N.J. , Aug. 3, 2015 ... Bouryal has been named Chief Corporate Brand and ... the firm,s executive leadership team, Bouryal will lead the ... organization builds on its transition to an independent company ... will report to Chairman and Chief Executive Officer Dr. ...
Breaking Medicine Technology:DURECT Corporation Announces Second Quarter 2015 Financial Results and Update of Programs 2DURECT Corporation Announces Second Quarter 2015 Financial Results and Update of Programs 3DURECT Corporation Announces Second Quarter 2015 Financial Results and Update of Programs 4DURECT Corporation Announces Second Quarter 2015 Financial Results and Update of Programs 5DURECT Corporation Announces Second Quarter 2015 Financial Results and Update of Programs 6DURECT Corporation Announces Second Quarter 2015 Financial Results and Update of Programs 7DURECT Corporation Announces Second Quarter 2015 Financial Results and Update of Programs 8DURECT Corporation Announces Second Quarter 2015 Financial Results and Update of Programs 9DURECT Corporation Announces Second Quarter 2015 Financial Results and Update of Programs 10Medical Simulation Market to see 14% CAGR to 2019 2Medical Simulation Market to see 14% CAGR to 2019 3Medical Simulation Market to see 14% CAGR to 2019 4Medical Simulation Market to see 14% CAGR to 2019 5Medical Simulation Market to see 14% CAGR to 2019 6Ortho Clinical Diagnostics Appoints Kristie Bouryal Chief Corporate Brand and Communications Officer 2
... was developed to address hematology needs ... of use, low maintenance, closed-tube sampling, ... are features expected in the modern ... fast access to results, sophisticated data ...
Inquire...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: